papaverine has been researched along with Pre-Eclampsia in 8 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Pre-Eclampsia: A complication of PREGNANCY, characterized by a complex of symptoms including maternal HYPERTENSION and PROTEINURIA with or without pathological EDEMA. Symptoms may range between mild and severe. Pre-eclampsia usually occurs after the 20th week of gestation, but may develop before this time in the presence of trophoblastic disease.
| Excerpt | Relevance | Reference |
|---|---|---|
| " For both normal pregnancy and pre-eclampsia, the response of pre-constricted arteries to the endothelium-dependent vasodilator, bradykinin, was minimal." | 3.71 | Functional characteristics of chorionic plate placental arteries from normal pregnant women and women with pre-eclampsia. ( Baker, PN; Crocker, IP; Ong, SS; Warren, AY, 2002) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (87.50) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ong, SS | 1 |
| Crocker, IP | 1 |
| Warren, AY | 1 |
| Baker, PN | 1 |
| URANGAIMAZ, FA | 2 |
| TONNELIER, E | 1 |
| KLAUER, D | 1 |
| CHEKERDEMIAN, M | 1 |
| MARZETTI, L | 1 |
| BENAGIANO, G | 1 |
| McCALL, ML | 2 |
| FINCH, V | 1 |
| TAYLOR, HW | 2 |
| FINCH, TV | 1 |
| TIMONEN, S | 1 |
| SCHRODERUS, KA | 1 |
| Carol, W | 1 |
| Ferrero, A | 1 |
| Marzullo, C | 1 |
| Salmoiraghi, ML | 1 |
8 other studies available for papaverine and Pre-Eclampsia
| Article | Year |
|---|---|
Functional characteristics of chorionic plate placental arteries from normal pregnant women and women with pre-eclampsia.
Topics: Adult; Analysis of Variance; Arteries; Bradykinin; Chorion; Endothelium, Vascular; Female; Humans; M | 2002 |
[THERAPEUTICS OF ARTERIAL HYPERTENSION IN PREGNANCY].
Topics: Female; Guanethidine; Hibernation; Humans; Hydralazine; Hypertension; Hypothermia, Induced; Maternal | 1964 |
[CLINICAL EVALUATION OF THE USE OF A DRUG WITH FIBRINOLYTIC ACTION IN THE THERAPY OF GESTOSIS IN THE THIRD TRIMESTER].
Topics: Antihypertensive Agents; Diuretics; Drug Therapy; Female; Humans; Niacin; Nicotinic Acids; Papaverin | 1964 |
The cerebral effects of papaverine hydrochloride in toxemia of pregnancy.
Topics: Brain; Female; Humans; Papaverine; Pre-Eclampsia; Pregnancy; Sepsis; Toxemia | 1951 |
The cerebral effects of papaverine hydrochloride in toxemia of pregnancy.
Topics: Cerebral Arteries; Cerebral Veins; Female; Humans; Papaverine; Pre-Eclampsia; Pregnancy; Veins | 1951 |
The effect of papaverin on the circulation of pre-eclamptic and eclamptic patients.
Topics: Eclampsia; Female; Humans; Papaverine; Pre-Eclampsia; Pregnancy | 1950 |
[Obstetrical emergencies, concerning the mother].
Topics: Acute Kidney Injury; Blood Coagulation Disorders; Calcium; Embolism, Amniotic Fluid; Emergencies; Fe | 1975 |
[Intensive therapy of gestoses. Our experience in the years 1969-1971].
Topics: Betamethasone; Brain Edema; Diazepam; Ergoloid Mesylates; Female; Furosemide; Humans; Mannitol; Papa | 1971 |