papaverine has been researched along with Myasthenia Gravis in 2 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Myasthenia Gravis: A disorder of neuromuscular transmission characterized by fatigable weakness of cranial and skeletal muscles with elevated titers of ACETYLCHOLINE RECEPTORS or muscle-specific receptor tyrosine kinase (MuSK) autoantibodies. Clinical manifestations may include ocular muscle weakness (fluctuating, asymmetric, external ophthalmoplegia; diplopia; ptosis; and weakness of eye closure) and extraocular fatigable weakness of facial, bulbar, respiratory, and proximal limb muscles. The disease may remain limited to the ocular muscles (ocular myasthenia). THYMOMA is commonly associated with this condition.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hokkanen, E | 1 |
| Vapaatalo, H | 2 |
| Anttila, P | 1 |
1 review available for papaverine and Myasthenia Gravis
| Article | Year |
|---|---|
Role of cyclic nucleotides in the nervous system.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Brain; Cyclic AMP; Cyclic GMP; Diaphragm; Humans; Muscle | 1974 |
1 other study available for papaverine and Myasthenia Gravis
| Article | Year |
|---|---|
On the possible role of cyclic AMP in the neuromuscular transmission and in the treatment of myasthenia gravis.
Topics: Cyclic AMP; Humans; Muscle Contraction; Myasthenia Gravis; Papaverine; Stimulation, Chemical; Synapt | 1972 |