papaverine has been researched along with Muscle Spasticity in 2 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Muscle Spasticity: A form of muscle hypertonia associated with upper MOTOR NEURON DISEASE. Resistance to passive stretch of a spastic muscle results in minimal initial resistance (a free interval) followed by an incremental increase in muscle tone. Tone increases in proportion to the velocity of stretch. Spasticity is usually accompanied by HYPERREFLEXIA and variable degrees of MUSCLE WEAKNESS. (From Adams et al., Principles of Neurology, 6th ed, p54)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| DE LA FUENTE, H | 1 |
| BALDINI, BE | 1 |
| ALT, L | 1 |
| KOLLMANN, HJ | 1 |
2 other studies available for papaverine and Muscle Spasticity
| Article | Year |
|---|---|
[Spastic algomenorrhea. Its treatment with a synthetic spasmolytic].
Topics: Dysmenorrhea; Female; Humans; Muscle Spasticity; Papaverine; Parasympatholytics | 1963 |
[Treatment of spastic vascular diseases].
Topics: Alkaloids; Atropa belladonna; Barbiturates; Humans; Muscle Spasticity; Nitrites; Papaverine; Parasym | 1955 |