papaverine has been researched along with Muscle Cramp in 5 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Muscle Cramp: A sustained and usually painful contraction of muscle fibers. This may occur as an isolated phenomenon or as a manifestation of an underlying disease process (e.g., UREMIA; HYPOTHYROIDISM; MOTOR NEURON DISEASE; etc.). (From Adams et al., Principles of Neurology, 6th ed, p1398)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| HARTWEGER, EW | 1 |
| Lejay, P | 1 |
| Viel, C | 1 |
| Uchida-Ernouf, G | 1 |
| Piccinelli, A | 1 |
| Neri, G | 1 |
| Agnoli, A | 1 |
| Stern, FH | 2 |
3 trials available for papaverine and Muscle Cramp
| Article | Year |
|---|---|
[Long-term medical treatment of acute cerebrovascular disease sequelae (comparison papaverine-piribedil].
Topics: Cerebrovascular Circulation; Cerebrovascular Disorders; Clinical Trials as Topic; Dioxoles; Drug Eva | 1974 |
Leg cramps in geriatric diabetics with peripheral vascular ischemia: treatment.
Topics: Aged; Clinical Trials as Topic; Delayed-Action Preparations; Diabetic Angiopathies; Female; Humans; | 1966 |
Further evaluation of papaverine for peripheral vascular ischemia.
Topics: Aged; Clinical Trials as Topic; Diabetes Complications; Female; Humans; Intermittent Claudication; I | 1967 |
2 other studies available for papaverine and Muscle Cramp
| Article | Year |
|---|---|
[Effective spasmolysis with Medition].
Topics: Meprobamate; Muscle Cramp; Papaverine; Parasympatholytics; Reserpine | 1963 |
[New analogs of papaverine: synthesis, pharmacological and conformational study of benzyl-4-isoquinolines substituted in the 1 or 3 position].
Topics: Animals; Guinea Pigs; Isoquinolines; Male; Mice; Muscle Cramp; Papaverine; Parasympatholytics | 1977 |