papaverine has been researched along with Muscle Contraction in 429 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Experiments were carried out in vitro on a new antispasmodic drug, 2-(diethylamino)-1-methylethyl-cis-1-hydroxy[bicyclohexyl] -2-carboxylate (rociverine), to elucidate further the mechanism of its smooth-muscle relaxation." | 7.67 | Mechanism of smooth muscle relaxation by rociverine. ( Brunori, P; D'Agostino, G; Grana, E; Santagostino Barbone, MG; Subissi, A; Zonta, F, 1984) |
| "Melatonin treatment strengthened contraction responses, but did not affect relaxation responses in rat tracheal preparations." | 5.38 | The achilles heel in melatonin: asthma. ( Belgin Yildirim, F; Karasu-Minareci, E; Kaya, Y, 2012) |
| " For both normal pregnancy and pre-eclampsia, the response of pre-constricted arteries to the endothelium-dependent vasodilator, bradykinin, was minimal." | 3.71 | Functional characteristics of chorionic plate placental arteries from normal pregnant women and women with pre-eclampsia. ( Baker, PN; Crocker, IP; Ong, SS; Warren, AY, 2002) |
| " Intraarterial infusion of papaverine relieves cerebral vasospasms by inhibiting smooth muscle contractions and it may simultaneously lead to a disruption of BBB permeability." | 3.71 | Quantitative analysis of papaverine-mediated blood-brain barrier disruption in rats. ( Bhattacharjee, AK; Ehara, K; Ikeda, M; Kondoh, T; Nagashima, T; Tamaki, N, 2001) |
| "An in vitro constant-flow, alternatively constant-pressure, perfusion method for studying microvascular myogenic responsiveness in otherwise intact rat hindquarters was used to explore how three types of influences affect the pressure-flow induced enhancements of myogenic tone: (1) Changes of potassium concentration over the range 2-50 mmol; (2) Whether myogenic responsiveness, which is fairly weak during these conditions of high shear rates, is enhanced by blockade of endothelial prostacyclin and nitrous oxide formation; (3) Whether some of the drawbacks of the constant-flow technique, like rapid edema formation, is offset by a constant-pressure variant." | 3.68 | Myogenic responsiveness in rat hindquarter vessels during constant-flow and constant-pressure perfusion in vitro; effects of various potassium concentrations and of endothelial nitrous oxide blockade. ( Folkow, B; Johnsson, E; Karlström, G, 1991) |
| "Experiments were carried out in vitro on a new antispasmodic drug, 2-(diethylamino)-1-methylethyl-cis-1-hydroxy[bicyclohexyl] -2-carboxylate (rociverine), to elucidate further the mechanism of its smooth-muscle relaxation." | 3.67 | Mechanism of smooth muscle relaxation by rociverine. ( Brunori, P; D'Agostino, G; Grana, E; Santagostino Barbone, MG; Subissi, A; Zonta, F, 1984) |
| " For this reason we have examined these relationships on segments of the abdominal aorta, the carotid artery, and the tail artery of normotensive rats in vitro under the condition of strong smooth muscle activation induced by norepinephrine (NE), and during smooth muscle relaxation induced by papaverine (PAP)." | 3.66 | Mechanical properties of arteries. ( Bauer, RD; Busse, R; Schabert, A, 1982) |
| "The mode of action of papaverine on smooth muscle relaxation was examined through analyzing its effects on caffeine-induced contraction of guinea pig taenia coli, which might be due to calcium ion mobilized from intracellular store sites." | 3.66 | Mechanism of relaxant action of papaverine. Effect on caffeine-induced contraction of guinea pig taenia coli. ( Kubota, K; Sunagane, N; Uruno, T, 1982) |
| "Melatonin treatment strengthened contraction responses, but did not affect relaxation responses in rat tracheal preparations." | 1.38 | The achilles heel in melatonin: asthma. ( Belgin Yildirim, F; Karasu-Minareci, E; Kaya, Y, 2012) |
| "It is now well established that hydrocephalus is associated with impaired bladder function." | 1.35 | Alterations in the mechanical properties of bladder smooth muscle in hydrocephalus rat model. ( Etuş, V; Tugay, M; Tugay, S; Utkan, T; Yazir, Y, 2008) |
| "It has been demonstrated that long-term administration of doxazosin, an alpha 1 adrenoceptor antagonist, causes an up-regulation in the expression of alpha 1 adrenoceptor subtype mRNAs in the rat genitourinary tract." | 1.34 | Contractile responses of rabbit bladder neck to adrenaline, acetylcholine and papaverine after doxazosin treatment. ( Ali Onur, M; Eroglu, M; Kandirali, E; Metin, A; Semercioz, A; Sezgin, A, 2007) |
| "Isoliquiritigenin was isolated from an aqueous extract of licorice as a potent relaxant, which inhibited the contraction induced by various types of stimulants, such as CCh, KCl, and BaCl2 with IC50 values of 4." | 1.34 | Isoliquiritigenin, one of the antispasmodic principles of Glycyrrhiza ularensis roots, acts in the lower part of intestine. ( Akao, T; He, JX; Nagai, H; Sato, Y; Tani, T, 2007) |
| "An association between chronic renal failure (CRF) and gastroesophageal reflux (GER) is well known." | 1.34 | Effect of chronic renal failure on foregut smooth muscle reactivity: an experimental study. ( Tugay, M; Utkan, T; Yazir, Y; Yildiz, F, 2007) |
| "Isovitexin was devoid of activity on duodenums." | 1.34 | The spasmolytic effect of Aloysia citriodora, Palau (South American cedrón) is partially due to its vitexin but not isovitexin on rat duodenums. ( Conforti, P; Consolini, AE; Ragone, MI; Sella, M; Volonté, MG, 2007) |
| "Papaverine treatment (1 x 10(-7) - 5 x 10(-7) - 1 x 10(-6) M) before or after the opioid agonists was able of both preventing and reversing the naloxone-induced contracture after exposure to mu (morphine and DAGO) or k (U50-488H) opiate agonists in a concentration-dependent fascion." | 1.32 | The effect of papaverine on acute opiate withdrawal in guinea pig ileum. ( Capasso, A; Loizzo, A, 2003) |
| "Allergic rhinitis, also known as hay fever, rose fever or summer catarrh, is a major challenge to health professionals." | 1.32 | Mast cell stabilization, lipoxygenase inhibition, hyaluronidase inhibition, antihistaminic and antispasmodic activities of Aller-7, a novel botanical formulation for allergic rhinitis. ( Amit, A; Bagchi, D; Bagchi, M; D'Souza, P; Pratibha, N; Saxena, VS; Stohs, SJ, 2003) |
| "Treatment with melatonin (EC(50) 4." | 1.32 | Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum. ( Ayanğolu-Dülger, G; Paskaloglu, K; Sener, G, 2004) |
| " Dilations to sodium nitroprusside and C-type natriuretic peptide were significantly reduced (by 10+/-2% and 35+/-6%), whereas dose-response curves for papaverine and ACh were shifted to the right, despite unchanged increases in endothelial Ca(2+) after ACh." | 1.31 | Oxidized LDL increases the sensitivity of the contractile apparatus in isolated resistance arteries for Ca(2+) via a rho- and rho kinase-dependent mechanism. ( Bolz, SS; de Wit, C; Derwand, R; Galle, J; Pohl, U, 2000) |
| "The isoproterenol effects were blocked by the antagonist propranolol." | 1.31 | Systemic and topical drug administration in the pig ureter: effect of phosphodiesterase inhibitors alpha1, beta and beta2-adrenergic receptor agonists and antagonists on the frequency and amplitude of ureteral contractions. ( Abel, D; Danuser, H; Mettler, D; Scholtysik, G; Studer, UE; Walter, B; Weiss, R, 2001) |
| " The dose-response curve to methoxamine (3-300 micrograms kg-1, i." | 1.29 | Mechanism of the cardiovascular activity of laudanosine: comparison with papaverine and other benzylisoquinolines. ( Chuliá, S; D'Ocon, P; Ivorra, MD; Lugnier, C; Noguera, MA; Vila, E, 1994) |
| "Papaverine, which is a smooth muscle relaxant, also acted as an antagonist." | 1.29 | A possible approach to the suppression of side effects induced by PGE1. ( Kubota, M; Nakabou, Y; Ojima, M; Takada, K, 1995) |
| "Histamine is a vasoactive amine which is endogenously produced in many organs including the penis." | 1.29 | Characterization and function of histamine receptors in corpus cavernosum. ( Carson, CC; Davies, MG; Hagen, PO; Kim, YC; Lee, TH, 1995) |
| "Higenamine was least potent in inhibition of Ca(2+)-induced contraction in high K+ depolarized aorta." | 1.29 | Different pharmacological characteristics of structurally similar benzylisoquinoline analogs, papaverine, higenamine, and GS 389, on isolated rat aorta and heart. ( Chang, KC; Chong, WS; Lee, IJ, 1994) |
| "When papaverine was washed out, a second application of 10(-4) M histamine also induced transient increases in [Ca2+]i and force." | 1.29 | Relationship between cytosolic calcium concentration and force in the papaverine-induced relaxation of medial strips of pig coronary artery. ( Aoki, H; Kanaide, H; Kobayashi, S; Nishimura, J, 1994) |
| "Circular muscle strips from achalasia patients contracted during field stimulation, an effect that was caused by muscarinic receptor activation." | 1.28 | Effects of postganglionic nerve stimulation in oesophageal achalasia: an in vitro study. ( Andersson, KE; Forman, A; Funch-Jensen, P; Raundahl, U; Tłottrup, A, 1990) |
| "When tiropramide was added during the sustained phase of the K+ (60 mM)-contracture, IC50 values of tiropramide for the contraction and the increased fluorescence were 1." | 1.28 | Possible mechanisms of action of the antispasmodic agent tiropramide in the isolated detrusor from rats. ( Kubota, K; Matsuoka, Y; Nagahamaya, K; Shirane, M; Sunagane, N; Tsunematsu, R; Uruno, T; Wada, K, 1992) |
| "Cromakalim was three to four times more potent than pinacidil." | 1.28 | K(+)-channel openers for relaxation of isolated penile erectile tissue from rabbit. ( Andersson, KE; Fovaeus, M; Hedlund, H; Holmquist, F, 1990) |
| "Papaverine is a non-specific smooth muscle relaxant and is thought to act at a site beyond the receptor sites on the cell membrane." | 1.28 | Effects of papaverine on human isolated bladder muscle. ( Hertle, L; Nawrath, H, 1990) |
| "Indomethacin pretreatment did not cause changes in responsiveness or sensitivity of lung parenchymal strips from normal or sensitized guinea-pigs to the agonists tested." | 1.28 | Modification by indomethacin of airway contractile responses in normal and sensitized guinea-pigs. ( Cortijo, J; Esplugues, J; Morcillo, EJ; Ortiz, JL; Pascual, R; Perpiñá, M; Sanz, C; Sarría, B, 1989) |
| "We conclude that diabetic men with impotence have impairment in both the autonomic and the endothelium-dependent mechanisms that mediate the relaxation of the smooth muscle of the corpora cavernosa." | 1.28 | Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence. ( Azadzoi, K; Cohen, RA; Goldstein, I; Krane, RJ; Saenz de Tejada, I, 1989) |
| "Treatment with papaverine induced an equal inhibition on the phasic and tonic components of Ba contractions and the Ba contraction in the Ca-free solution." | 1.27 | [Ba-induced contraction of the guinea pig ileal longitudinal muscle and its inhibition by D-600, benactyzine, and papaverine]. ( Mukai, T; Takagi, K, 1983) |
| "Histamine has a greater relaxant effect on mesenteric artery strips at 22 degrees than at 38 degrees, normally." | 1.27 | Dibenamine enhancement of histamine-induced relaxation of the rabbit mesenteric artery. ( Christiansen, VJ; Horst, MA; Robinson, C, 1983) |
| " It is possible that Abana treatment for 3 days has an action similar to that of chronic administration of isoprenaline (down regulation of beta receptors)." | 1.27 | Effects of Abana, an Ayurvedic preparation, on rabbit atrium and intestine. ( Gulati, OD; Hemavathi, KG; Pasnani, JS; Rajani, AP, 1988) |
| " TM-906 noncompetitively antagonized the contractile response to methacholine, and it caused a parallel shift of dose-response curves for the contractile response to CaCl2 to higher concentrations." | 1.27 | Effects of trimebutine maleate (TM-906) on the smooth muscles of isolated guinea pig gallbladder. ( Magaribuchi, T; Takenaga, H; Tamaki, H, 1984) |
| " ALK-1 and papaverine promoted a dose-dependent flattening of the dose-response curves obtained to acetylcholine and histamine on ileum strips and of the dose-response curves to acetylcholine and oxytocin on uterine strips." | 1.27 | Antispasmodic effects of an alkaloid extracted from Phyllanthus sellowianus: a comparative study with papaverine. ( Calixto, JB; Neto, AS; Rae, GA; Valle, RM; Yunes, RA, 1984) |
| "Benactyzine was a specific agent against the Ca(-) ." | 1.27 | [Histamine-induced contraction of the guinea pig taenia coli and its inhibition by D-600, papaverine, and benactyzine]. ( Mukai, T; Takagi, K, 1983) |
| "Papaverine at 150 micron was without significant effect on Ca binding by either microsomes or mitochondria isolated from both vas deferens and urinary bladder smooth muscle." | 1.27 | Inhibition by papaverine of calcium movements and tension in the smooth muscles of rat vas deferens and urinary bladder. ( Huddart, H; Langton, PD; Saad, KH, 1984) |
| "Papaverine was shown to be the substance able to cause the biggest relaxation effect." | 1.27 | Relaxation of isolated corpus cavernosum induced by smooth-muscle relaxant drugs. A comparative study. ( Barbanti, G; Beneforti, P; Lapini, A; Turini, D, 1988) |
| " Fusaric acid produced a shift to the right and down in the dose-response curves to all tested agonists, and antagonized acetylcholine and serotonin most effectively among these agonists." | 1.26 | Relaxation of isolated rabbit arteries by fusaric (5-butylpicolinic) acid. ( Asano, M; Hidaka, H, 1976) |
| "Papaverine-treated veins which were subjected to brief periods of distension at pressures of 100 mmHg or greater demonstrated large gaps between the endothelial lining cells." | 1.26 | Vein contraction and smooth muscle cell extensions as causes of endothelial damage during graft preparation. ( Baumann, FG; Catinella, FP; Cunningham, JN; Spencer, FC, 1981) |
| " Papaverine and theophylline caused a decrease both in the maximum height and the slope of dose-response curves induced by the three stimulants, and an increase in the cyclic AMP levels." | 1.26 | Smooth muscle relaxing drugs and guinea pig ileum. ( Goto, J; Mukai, T; Takagi, K; Yamaguchi, E, 1981) |
| " In lower concentrations (10(-6)-10(-5) M), the compounds did not affect the dose-response curves of carbachol and isoprenaline." | 1.26 | Antispasmodic effects of valeriana compounds: an in-vivo and in-vitro study on the guinea-pig ileum. ( Hazelhoff, B; Malingré, TM; Meijer, DK, 1982) |
| "Papaverine was assumed to produce a relaxation through augmentation of the calcium binding to the intercellular store sites for calcium as well as through inhibition of the calcium influx." | 1.26 | A comparison of the differential effects of nitroglycerin, nifedipine and papaverine on contractures induced in vascular and intestinal smooth muscle by potassium and lanthanum. ( Imai, S; Kitagawa, T, 1981) |
| "Papaverine was equally effective in reducing the contractile response evoked from both thoracic aorta and mesenteric arteries by the two modes of stimulation." | 1.26 | A comparison of the inhibitory effect of cinnarizine and papaverine on the noradrenaline- and calcium-evoked contraction of isolated rabbit aorta and mesenteric arteries. ( Broekaert, A; Godfraind, T, 1979) |
| "4 The dose-response curve to glucagon remained parallel in the presence of papaverine (2." | 1.26 | A new bioassay for glucagon. ( Gagnon, G; Regoli, D; Rioux, F, 1978) |
| " LD50 and ileum ED50, was greater than the therapeutic index of papaverine." | 1.25 | [Action on the isolated guinea-pig ileum and toxicity of some derivatives of 1,5-bis-(3,4-methylendioxyphenyl)-n. pentane]. ( Agozzino, S; Di Carlo, R; Reboani, C, 1975) |
| "Himachalol has been identified as the major antispasmodic constituent in the wood of Cedrus deodara." | 1.25 | Spasmolytic constituents of Cedrus deodara (Roxb.) Loud: pharmacological evaluation of himachalol. ( Dhawan, BN; Kar, K; Kulshrestha, DK; Patnaik, GK; Puri, VN; Rastogi, RP; Sur, RN, 1975) |
| "Prevention of premature labor is of considerable interest in research and clinics." | 1.25 | The treatment of threatened premature labor by tocolytics, Ca++-Antagonists and anti-inflammatory drugs. ( Mosler, KH, 1975) |
| " In these studies, it is shown that increasing concentrations of carbamylcholine (carbachol) result in a shift to the right of the dose-response curves to (-)-isoproterenol and (-)-soterenol and a reduction of the maximum degree of relaxation produced by these agonists relative to that produced by papaverine." | 1.25 | On the use of functional antagonism to estimate dissociation constants for beta adrenergic receptor agonists in isolated guinea-pig trachea. ( Buckner, CK; Saini, RK, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 321 (74.83) | 18.7374 |
| 1990's | 59 (13.75) | 18.2507 |
| 2000's | 36 (8.39) | 29.6817 |
| 2010's | 12 (2.80) | 24.3611 |
| 2020's | 1 (0.23) | 2.80 |
| Authors | Studies |
|---|---|
| Temple, DL | 1 |
| Yevich, JP | 1 |
| Catt, JD | 1 |
| Owens, D | 1 |
| Hanning, C | 1 |
| Covington, RR | 1 |
| Seidehamel, RJ | 1 |
| Dungan, KW | 1 |
| Hernández-Romero, Y | 1 |
| Rojas, JI | 1 |
| Castillo, R | 1 |
| Rojas, A | 1 |
| Mata, R | 1 |
| Gledacheva, VN | 1 |
| Stefanova, ID | 1 |
| Slavchev, VI | 1 |
| Ardasheva, RG | 1 |
| Kristev, AD | 1 |
| Nikolova, SA | 1 |
| Saracheva, KE | 1 |
| Dimitrova, DS | 1 |
| Patai, Z | 2 |
| Guttman, A | 2 |
| Mikus, EG | 2 |
| Vecherskiĭ, IuIu | 1 |
| Andreev, SL | 1 |
| Zatolokin, VV | 1 |
| Gusakova, SV | 1 |
| Kovalev, IV | 1 |
| Eremenko, KV | 1 |
| Dronova, IV | 1 |
| Kaneda, T | 4 |
| Saito, E | 1 |
| Kanda, H | 1 |
| Urakawa, N | 8 |
| Shimizu, K | 5 |
| Gilani, AH | 4 |
| Shah, AJ | 3 |
| Zubair, A | 1 |
| Khalid, S | 1 |
| Kiani, J | 1 |
| Ahmed, A | 1 |
| Rasheed, M | 1 |
| Ahmad, VU | 1 |
| Baccari, MC | 1 |
| Bani, D | 1 |
| Calamai, F | 1 |
| Matera, MG | 1 |
| Calzetta, L | 1 |
| Parascandolo, V | 1 |
| Curradi, G | 1 |
| Rogliani, P | 1 |
| Cazzola, M | 1 |
| Ertan, AA | 1 |
| Beriat, NC | 1 |
| Gürpinar, A | 1 |
| Onur, MA | 1 |
| Cehreli, MC | 1 |
| Hayasaka, R | 1 |
| Nagai, Y | 1 |
| Tajima, T | 1 |
| Nakajyo, S | 4 |
| Brankovic, S | 1 |
| Kitic, D | 1 |
| Radenkovic, M | 1 |
| Veljkovic, S | 1 |
| Jankovic, T | 1 |
| Savikin, K | 1 |
| Zdunic, G | 1 |
| Khan, M | 1 |
| Khan, AU | 1 |
| Kedia, GT | 1 |
| Ückert, S | 3 |
| Polat, H | 1 |
| Merseburger, AS | 1 |
| Kuczyk, MA | 1 |
| Karasu-Minareci, E | 1 |
| Kaya, Y | 1 |
| Belgin Yildirim, F | 1 |
| Kelicen, P | 1 |
| Pekiner, C | 1 |
| Sarioğlu, Y | 2 |
| Uma, S | 1 |
| Noda, K | 1 |
| Takebe, M | 1 |
| Oka, M | 1 |
| Hirouchi, M | 1 |
| Ukai, Y | 1 |
| Toda, N | 6 |
| Ong, SS | 1 |
| Crocker, IP | 2 |
| Warren, AY | 2 |
| Baker, PN | 2 |
| Gao, YJ | 1 |
| Yang, H | 1 |
| Teoh, K | 1 |
| Lee, RM | 1 |
| Capasso, A | 1 |
| Loizzo, A | 1 |
| BANERJEE, AK | 3 |
| LEWIS, JJ | 1 |
| MURNAGHAN, MF | 2 |
| SUTTER, MC | 1 |
| Amit, A | 1 |
| Saxena, VS | 1 |
| Pratibha, N | 1 |
| D'Souza, P | 1 |
| Bagchi, M | 1 |
| Bagchi, D | 1 |
| Stohs, SJ | 1 |
| Kaur, J | 1 |
| Ghosh, NN | 1 |
| Chandra, R | 1 |
| Paskaloglu, K | 1 |
| Sener, G | 1 |
| Ayanğolu-Dülger, G | 1 |
| Waseda, K | 1 |
| Takeuchi, T | 1 |
| Ohta, M | 1 |
| Okishio, Y | 1 |
| Fujita, A | 1 |
| Hata, F | 1 |
| Takewaki, T | 1 |
| Takeuchi, Y | 1 |
| Matsui, H | 1 |
| Dahl, SL | 1 |
| Chen, Z | 1 |
| Solan, AK | 1 |
| Brockbank, KG | 1 |
| Niklason, LE | 1 |
| Song, YC | 1 |
| Liu, JQ | 1 |
| Yang, D | 1 |
| Folz, RJ | 1 |
| Bertrand, PP | 1 |
| Eroglu, M | 1 |
| Sezgin, A | 1 |
| Semercioz, A | 1 |
| Metin, A | 1 |
| Kandirali, E | 1 |
| Ali Onur, M | 1 |
| Sato, Y | 1 |
| He, JX | 1 |
| Nagai, H | 1 |
| Tani, T | 1 |
| Akao, T | 1 |
| Tugtepe, H | 1 |
| Tugay, M | 3 |
| Bozkurt, S | 1 |
| Yildiz, F | 2 |
| Utkan, T | 4 |
| Yegen, BC | 1 |
| Dagli, TE | 1 |
| Yazir, Y | 2 |
| Ragone, MI | 1 |
| Sella, M | 1 |
| Conforti, P | 1 |
| Volonté, MG | 1 |
| Consolini, AE | 1 |
| Andrade, EL | 1 |
| Ferreira, J | 1 |
| Santos, AR | 1 |
| Calixto, JB | 2 |
| Tugay, S | 1 |
| Etuş, V | 1 |
| Zhao, J | 1 |
| Liao, D | 1 |
| Gregersen, H | 1 |
| Mosler, KH | 2 |
| Zimmer, F | 1 |
| Castell, R | 1 |
| Ewald, P | 1 |
| Büttner, P | 1 |
| Wohl, AJ | 1 |
| Hausler, LM | 1 |
| Roth, FE | 1 |
| Fermum, R | 3 |
| Möritz, KU | 3 |
| Schäfer, U | 1 |
| Leibelt, M | 1 |
| Fujioka, M | 1 |
| Hertle, L | 3 |
| Nawrath, H | 3 |
| Tofelde, U | 1 |
| Dadkar, NK | 1 |
| Aroskar, VA | 1 |
| Dohadwalla, AN | 1 |
| Takayanagi, I | 18 |
| Hisayama, T | 1 |
| Yoshida, Y | 3 |
| Koike, K | 2 |
| Lucchelli, A | 2 |
| Zonta, F | 4 |
| Grana, E | 5 |
| Turba, C | 1 |
| Pagella, P | 1 |
| Downing, OA | 1 |
| Morris, JS | 1 |
| Kaneko, M | 2 |
| Ohashi, M | 3 |
| Sato, R | 1 |
| Sunagane, N | 6 |
| Sakata, T | 1 |
| Uruno, T | 8 |
| Kubota, K | 10 |
| Kizawa, Y | 1 |
| Sugimoto, J | 1 |
| Syoji, N | 1 |
| Mizuno, K | 1 |
| Morita, M | 2 |
| Manzini, S | 1 |
| Maggi, CA | 1 |
| Meli, A | 1 |
| Robinson, C | 1 |
| Christiansen, VJ | 1 |
| Horst, MA | 1 |
| Cohen, ML | 5 |
| Landry, AS | 2 |
| Mukai, T | 4 |
| Yamaguchi, E | 1 |
| Goto, J | 1 |
| Takagi, K | 12 |
| Albrecht, T | 1 |
| Speelman, DJ | 1 |
| Steinsland, OS | 1 |
| Heaslip, RJ | 1 |
| Rahwan, RG | 1 |
| Paul, RJ | 1 |
| Hellstrand, P | 2 |
| D'Agostino, G | 3 |
| Dondi, G | 1 |
| Gaion, RM | 1 |
| Trento, M | 1 |
| Takenaga, H | 3 |
| Magaribuchi, T | 3 |
| Tamaki, H | 3 |
| Yunes, RA | 1 |
| Neto, AS | 1 |
| Valle, RM | 1 |
| Rae, GA | 1 |
| Santagostino Barbone, MG | 1 |
| Brunori, P | 1 |
| Subissi, A | 1 |
| Kometani, A | 1 |
| Suzuki, A | 2 |
| Ozaki, H | 1 |
| Fortes, ZB | 1 |
| Garcia Leme, J | 1 |
| Scivoletto, R | 1 |
| Goldenberg, MM | 4 |
| Meurer, RD | 1 |
| Yamakado, T | 1 |
| Nishikawa, M | 1 |
| Azuma, H | 2 |
| Hidaka, H | 2 |
| Huddart, H | 2 |
| Langton, PD | 2 |
| Saad, KH | 1 |
| Skalak, TC | 1 |
| Schmid-Schönbein, GW | 1 |
| Zweifach, BW | 1 |
| Takeyasu, K | 2 |
| Uchida, S | 2 |
| Lai, RT | 1 |
| Higuchi, H | 1 |
| Noguchi, Y | 1 |
| Yoshida, H | 2 |
| Imai, S | 2 |
| Kitagawa, T | 1 |
| Auguet, M | 1 |
| Clostre, F | 1 |
| Brading, AF | 1 |
| Burdyga, TV | 1 |
| Scripnyuk, ZD | 1 |
| de Souza, LC | 1 |
| Anderson Júnior, NC | 1 |
| Georgiade, NG | 1 |
| Towart, R | 1 |
| Perzborn, E | 1 |
| Bauer, RD | 2 |
| Busse, R | 2 |
| Schabert, A | 2 |
| Hazelhoff, B | 1 |
| Malingré, TM | 1 |
| Meijer, DK | 1 |
| Sattler, T | 1 |
| Kuromi, H | 1 |
| Rapoport, RM | 1 |
| Bevan, JA | 3 |
| Baumann, FG | 1 |
| Catinella, FP | 1 |
| Cunningham, JN | 1 |
| Spencer, FC | 1 |
| Kimura, I | 1 |
| Kimura, M | 1 |
| Yoshimura, Y | 1 |
| Nakazawa, S | 1 |
| Ichikawa, T | 1 |
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| Kametani, T | 1 |
| Kigasawa, K | 1 |
| Hiiragi, M | 1 |
| Aoyama, T | 1 |
| Kusama, O | 1 |
| Hennighausen, G | 1 |
| Vallvé, C | 1 |
| Amon, K | 1 |
| Amon, I | 1 |
| Carpenedo, F | 1 |
| Kasahara, A | 1 |
| Akashi, A | 1 |
| Hashizume, T | 1 |
| Yamaguchi, K | 1 |
| Shroishi, Y | 1 |
| Holmlund, D | 1 |
| Van Nueten, JM | 1 |
| Suchowsky, GK | 1 |
| Pegrassi, L | 1 |
| Bonsignori, A | 1 |
| Bertazzoli, C | 1 |
| Chieli, T | 1 |
| Zasztowt, O | 2 |
| Gaspa, U | 1 |
| Stafford, A | 1 |
4 reviews available for papaverine and Muscle Contraction
| Article | Year |
|---|---|
Cyclic GMP and gastric acid secretion.
Topics: Animals; Cyclic AMP; Cyclic GMP; Depression, Chemical; Gallbladder; Gastric Juice; Glycyrrhiza; Inte | 1974 |
Role of cyclic nucleotides in the nervous system.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Brain; Cyclic AMP; Cyclic GMP; Diaphragm; Humans; Muscle | 1974 |
Effects of papaverine on smooth muscle and their mechanisms.
Topics: Bucladesine; Calcium; Cell Membrane; Colon; Cyanides; Dinitrophenols; Electrolytes; Electrophysiolog | 1974 |
The role of calcium in the action of drugs on vascular smooth muscle.
Topics: Animals; Aorta; Calcium; Calcium Isotopes; Chlorpromazine; Cinnamates; In Vitro Techniques; Muscle C | 1972 |
5 trials available for papaverine and Muscle Contraction
| Article | Year |
|---|---|
Dilation of the internal mammary artery by external papaverine application to the pedicle--an improved method.
Topics: Adult; Aged; Analysis of Variance; Blood Flow Velocity; Coronary Artery Bypass; Dilatation; Female; | 1993 |
Reduction of neurologic injury after high-risk thoracoabdominal aortic operation.
Topics: Adult; Aged; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Cardiopulmonary Bypass; Cerebros | 1998 |
The effect of papaverine on the contraction of the human gallbladder.
Topics: Adult; Aged; Cholecystography; Female; Gallbladder; Humans; Male; Middle Aged; Muscle Contraction; M | 1978 |
Pharmacology of ethaverine HC1: human and animal studies.
Topics: Adult; Aged; Animals; Arterial Occlusive Diseases; Blood Circulation; Clinical Trials as Topic; Fema | 1975 |
[Manometric evaluation of the effects of intravenous administration of glucagon, buscopan and papaverine on the contractile activity of the sphincter of Oddi].
Topics: Adult; Aged; Butylscopolammonium Bromide; Common Bile Duct Diseases; Dipyrone; Drug Combinations; Fe | 1992 |
420 other studies available for papaverine and Muscle Contraction
| Article | Year |
|---|---|
Substituted 6,7-dihydroimidazo[1,2-a]purin-9(4H)-ones.
Topics: Animals; Bronchial Spasm; Bronchodilator Agents; Chemical Phenomena; Chemistry; Female; Guinea Pigs; | 1980 |
Spasmolytic effects, mode of action, and structure-activity relationships of stilbenoids from Nidema boothii.
Topics: Animals; Bibenzyls; Brain; Cattle; Dose-Response Relationship, Drug; Flavonoids; Guaiacol; Guinea Pi | 2004 |
Impact of a Newly Synthesized Molecule (2-chloro-N-(1-(3,4-dimethoxyphenyl) propan-2-yl)-2-phenylacetamide) on the Bioelectrogenesis and the Contractile Activity of Isolated Smooth Muscles.
Topics: Animals; Benzeneacetamides; Biomechanical Phenomena; Calcium; Male; Muscle Contraction; Muscle, Smoo | 2020 |
Assessment of the Airway Smooth Muscle Relaxant Effect of Drotaverine.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smoo | 2018 |
[In vitro study of the radial artery vasodilatory reactions].
Topics: Chlorpromazine; Dopamine Antagonists; Heparin; Humans; Muscle Contraction; Muscle, Smooth; Nifedipin | 2014 |
Effects of papaverine on carbachol- and high K+ -induced contraction in the bovine abomasum.
Topics: Abomasum; Adjuvants, Immunologic; Animals; Carbachol; Cattle; Cholinergic Agonists; Colforsin; Muscl | 2015 |
Potential L-Type Voltage-Operated Calcium Channel Blocking Effect of Drotaverine on Functional Models.
Topics: Animals; Calcium; Calcium Channel Blockers; Calcium Channels, L-Type; Calcium Chloride; Electrophysi | 2016 |
Chemical composition and mechanisms underlying the spasmolytic and bronchodilatory properties of the essential oil of Nepeta cataria L.
Topics: Animals; Bronchodilator Agents; Calcium Channels; Female; Guinea Pigs; Male; Muscle Contraction; Mus | 2009 |
Evidence for a modulatory role of orexin A on the nitrergic neurotransmission in the mouse gastric fundus.
Topics: Animals; Benzoxazoles; Carbachol; Cholinergic Agonists; Dimethylphenylpiperazinium Iodide; Electric | 2009 |
Relaxant effect of brain natriuretic peptide in nonsensitized and passively sensitized isolated human bronchi.
Topics: Bronchi; Bronchial Hyperreactivity; Carbachol; Histamine; Humans; Immunization, Passive; In Vitro Te | 2009 |
Vascular smooth muscle contraction/relaxation of rat carotid artery is not altered by bone grafting substitutes in vitro.
Topics: Animals; Biocompatible Materials; Bone Matrix; Bone Substitutes; Carotid Arteries; Ceramics; Dose-Re | 2010 |
Bronchodilatory effect of Acorus calamus (Linn.) is mediated through multiple pathways.
Topics: Acorus; Animals; Atropine; Bronchodilator Agents; Calcium Channel Blockers; Carbachol; Female; Guine | 2010 |
Effects of papaverine on twitches in mouse diaphragm.
Topics: Adenosine Triphosphate; Animals; Calcium; Cyclic AMP; Cyclic GMP; Diaphragm; Dose-Response Relations | 2010 |
Spasmolytic activity of the ethanol extract of Sideritis raeseri spp. raeseri Boiss. & Heldr. on the isolated rat ileum contractions.
Topics: Acetylcholine; Animals; Atropine; Barium Compounds; Chlorides; Ethanol; Histamine; Ileum; In Vitro T | 2011 |
Pharmacological explanation for the medicinal use of Juniperus excelsa in hyperactive gastrointestinal and respiratory disorders.
Topics: Animals; Bronchodilator Agents; Calcium Channel Blockers; Diarrhea; Gastrointestinal Diseases; Guine | 2012 |
The calcium channel blocking and phosphodiesterase inhibitory activities of the extract of Andropogon muricatus explains its medicinal use in airways disorders.
Topics: Andropogon; Animals; Asthma; Calcium Channel Blockers; Calcium Channels; Carbachol; Guinea Pigs; In | 2012 |
Evaluating the significance of cyclic adenosine monophosphate-mediated signaling in human prostate: a functional and biochemical study.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Aged; Benzamides; Colforsin; Cyclic AMP; Humans; In | 2012 |
The achilles heel in melatonin: asthma.
Topics: Acetylcholine; Animals; Asthma; Circadian Rhythm; Dose-Response Relationship, Drug; Injections, Intr | 2012 |
Omeprazole-induced relaxation in rat aorta is partly dependent on endothelium.
Topics: Acetylcholine; Animals; Cyclooxygenase Inhibitors; Endothelium, Vascular; Enzyme Inhibitors; In Vitr | 2002 |
Functional role of inhibitory and excitatory nerves in the porcine lower urinary tract.
Topics: Adrenergic alpha-Antagonists; Animals; Arginine; Atropine; Cyclic GMP; Dose-Response Relationship, D | 2002 |
Functional characteristics of chorionic plate placental arteries from normal pregnant women and women with pre-eclampsia.
Topics: Adult; Analysis of Variance; Arteries; Bradykinin; Chorion; Endothelium, Vascular; Female; Humans; M | 2002 |
Detrimental effects of papaverine on the human internal thoracic artery.
Topics: Animals; Apoptosis; Dogs; Endothelium, Vascular; Humans; Incidence; Mammary Arteries; Muscle Contrac | 2003 |
The effect of papaverine on acute opiate withdrawal in guinea pig ileum.
Topics: 3,4-Dichloro-N-methyl-N-(2-(1-pyrrolidinyl)-cyclohexyl)-benzeneacetamide, (trans)-Isomer; Acute Dise | 2003 |
INFLUENCE OF DRUGS ON 47-CA-2+ RELEASE FROM DEPOLARIZED INTESTINAL SMOOTH MUSCLE.
Topics: Acetylcholine; Animals; Calcium; Carbachol; Creatine; Creatinine; Epinephrine; Guinea Pigs; Histamin | 1964 |
NON-SPECIFIC EFFECTS OF THE TROPOLONES.
Topics: Animals; Arteries; Barium; Carbachol; Chelating Agents; Copper; Edetic Acid; Enzyme Inhibitors; Epin | 1964 |
THE PHARMACOLOGY OF ISOLATED VEINS.
Topics: Acetylcholine; Angiotensins; Animals; Arginine Vasopressin; Bradykinin; Cats; Epinephrine; Guinea Pi | 1965 |
Mast cell stabilization, lipoxygenase inhibition, hyaluronidase inhibition, antihistaminic and antispasmodic activities of Aller-7, a novel botanical formulation for allergic rhinitis.
Topics: Animals; Barium Compounds; Carbachol; Cetirizine; Chlorides; Dose-Response Relationship, Drug; Drug | 2003 |
Synthesis and antispasmodic activity evaluation of bis-(papaverine) analogues.
Topics: Animals; Guinea Pigs; Ileum; In Vitro Techniques; Inhibitory Concentration 50; Molecular Structure; | 2004 |
Melatonin treatment protects against diabetes-induced functional and biochemical changes in rat aorta and corpus cavernosum.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Blood Glucose; Body Weight; Diabetes Mellitus, Experimental | 2004 |
Participation of ATP in nonadrenergic, noncholinergic relaxation of longitudinal muscle of wistar rat jejunum.
Topics: Adenosine Phosphosulfate; Adenosine Triphosphate; Animals; Apamin; Atropine; Drug Administration Sch | 2005 |
Inhibitory mechanism of papaverine on carbachol-induced contraction in bovine trachea.
Topics: Adenosine Triphosphate; Animals; Calcium; Carbachol; Cattle; Cyclic AMP; Cyclic GMP; Female; In Vitr | 2005 |
Feasibility of vitrification as a storage method for tissue-engineered blood vessels.
Topics: Animals; Apoptosis; Biocompatible Materials; Biomechanical Phenomena; Carotid Arteries; Cell Adhesio | 2006 |
A novel bronchial ring bioassay for the evaluation of small airway smooth muscle function in mice.
Topics: Animals; Biological Assay; Boron Compounds; Bronchi; Bronchoconstrictor Agents; Calcium Channel Bloc | 2006 |
Real-time measurement of serotonin release and motility in guinea pig ileum.
Topics: Acetylcholine; Anesthetics, Local; Animals; Atropine; Electric Stimulation; Electrochemistry; Enteri | 2006 |
Contractile responses of rabbit bladder neck to adrenaline, acetylcholine and papaverine after doxazosin treatment.
Topics: Acetylcholine; Animals; Dose-Response Relationship, Drug; Doxazosin; Epinephrine; Male; Muscle Contr | 2007 |
Isoliquiritigenin, one of the antispasmodic principles of Glycyrrhiza ularensis roots, acts in the lower part of intestine.
Topics: Animals; beta-Glucosidase; Chalcones; Dose-Response Relationship, Drug; Glycoside Hydrolases; Glycyr | 2007 |
Esophageal smooth muscle reactivity is impaired in chronic reflux esophagitis by both receptor- and nonreceptor-mediated mechanisms.
Topics: Animals; Calcium Channels; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug; Esopha | 2007 |
Effect of chronic renal failure on foregut smooth muscle reactivity: an experimental study.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Cholinergic Agonists; Dose-Response Relationship, Drug | 2007 |
The spasmolytic effect of Aloysia citriodora, Palau (South American cedrón) is partially due to its vitexin but not isovitexin on rat duodenums.
Topics: Acetylcholine; Animals; Apigenin; Calcium Chloride; Dose-Response Relationship, Drug; Duodenum; Enzy | 2007 |
Pharmacological analysis of paregoric elixir and its constituents: in vitro and in vivo studies.
Topics: Analgesics; Analgesics, Opioid; Animals; Behavior, Animal; Chromatography, High Pressure Liquid; Dru | 2007 |
Alterations in the mechanical properties of bladder smooth muscle in hydrocephalus rat model.
Topics: Adrenergic beta-Agonists; Animals; Biomechanical Phenomena; Disease Models, Animal; Dose-Response Re | 2008 |
Phasic and tonic stress-strain data obtained in intact intestinal segment in vitro.
Topics: Animals; Biomechanical Phenomena; Calcium; Ileum; Jejunum; Male; Muscle Contraction; Muscle, Smooth; | 2008 |
Tocolysis.
Topics: Animals; Chlordiazepoxide; Diazepam; Female; Guinea Pigs; Humans; In Vitro Techniques; Muscle Contra | 1966 |
[Significance of the enlargement of the pregnant rat uterus in wall tension, elasticity and function of the myometrium].
Topics: Animals; Elasticity; Female; Muscle Contraction; Papaverine; Pregnancy; Pregnancy, Animal; Rats; Ute | 1966 |
Studies on the mechanism of antihypertensive action of diazoxide: in vitro vascular pharmacodynamics.
Topics: Animals; Aorta; Barium; Blood Pressure; Calcium; Diazoxide; Drug Antagonism; In Vitro Techniques; Mu | 1967 |
[Adenosine-3',5'-monophosphate content and muscle tension in isolated coronary arteries under the effect of lanthanum ions].
Topics: 1-Methyl-3-isobutylxanthine; Animals; Cattle; Coronary Vessels; Cyclic AMP; In Vitro Techniques; Iso | 1984 |
Lack of a causal relationship between the vasodilator effect of papaverine and cyclic AMP production in the dog basilar artery.
Topics: Animals; Basilar Artery; Calcium; Cyclic AMP; Dogs; Electric Stimulation; Electrophysiology; Evoked | 1984 |
Calcium channel blockade in smooth muscle of the human upper urinary tract. I. Effects on depolarization-induced activation.
Topics: Action Potentials; Adult; Aged; Calcium; Calcium Channel Blockers; Diltiazem; Gallopamil; Humans; Io | 1984 |
[Dissociation of the action of isoprenaline on muscle tension and adenosine-3',5'-monophosphate synthesis in isolated coronary arteries under the effect of diisopropylfluorophosphate].
Topics: Adenylyl Cyclases; Animals; Atropine; Cattle; Coronary Vessels; Cyclic AMP; In Vitro Techniques; Iso | 1984 |
Peripheral vascular smooth muscle relaxation in normotensive and hypertensive rats.
Topics: Adenosine; Animals; Desoxycorticosterone; Hypertension; Isoproterenol; Male; Mesenteric Arteries; Mu | 1980 |
Effects of nonspecific smooth muscle relaxants on calcium-uptake by microsomal fraction and their inhibitory action in rabbit taenia coli.
Topics: Action Potentials; Animals; Calcium; Cyclic AMP; Male; Microsomes; Muscle Contraction; Muscle, Smoot | 1980 |
Dualism in the alpha-adrenoceptor blocking action of dihydroergocristine.
Topics: Adrenergic alpha-Antagonists; Animals; Calcium; Dihydroergotoxine; In Vitro Techniques; Male; Muscle | 1981 |
The effect of indomethacin on contractions of guinea-pig stomach following cessation of vagal stimulation in the presence of hyoscine or pempidine.
Topics: Animals; Dinoprostone; Electric Stimulation; Female; Guinea Pigs; Indomethacin; Male; Muscle Contrac | 1981 |
Inhibition of Ca-movement and mechanical movement in rabbit taenia coli by a smooth muscle relaxant (suloctidil).
Topics: Animals; Calcium; Colon; Gallopamil; In Vitro Techniques; Male; Microsomes; Muscle Contraction; Musc | 1981 |
Contractile response of rabbit dilator pupillae muscle to isotonic high K or norepinephrine, and Ca movement.
Topics: Animals; Calcium; Cyclic AMP; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smo | 1982 |
Pharmacological characterization of ionophore X537A-induced contractile responses in isolated rabbit taenia coli and aorta.
Topics: Animals; Aorta, Thoracic; Colon; Gallopamil; In Vitro Techniques; Lasalocid; Male; Muscle Contractio | 1983 |
Mechanism of relaxant action of papaverine. III. Comparison of sodium ion dependencies on the relaxant effects of papaverine, Aspaminol and benactyzine in guinea-pig taenia coli.
Topics: Animals; Benactyzine; Calcium; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Intestines; Muscle Cont | 1983 |
A possible site of action of nicotine in the bronchial smooth muscle preparation of guinea-pig.
Topics: Acetylcholine; Animals; Bronchi; Cyclic GMP; Drug Interactions; Electric Stimulation; Guinea Pigs; I | 1983 |
The actions of D 600, aspaminol and papaverine on calcium-, potassium- and histamine-induced contractions of isolated rabbit basilar artery, aorta, taenia coli and tracheal smooth muscle.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Gallopamil; Histamine; In Vitro Techniques; Male | 1983 |
Increase in Ca2+ (Mg2+)-ATPase activity induced by a molsidomine derivative (SIN-1 A) and nitroglycerin in microsomal fraction of guinea-pig thoracic aorta.
Topics: Animals; Aorta, Thoracic; Ca(2+) Mg(2+)-ATPase; Calcium; Calcium-Transporting ATPases; Dinoprost; Fe | 1984 |
System and organ-selectivity of smooth muscle relaxants on in vitro spontaneously contracting preparations.
Topics: Animals; Calcium; Colon; Duodenum; Heart Atria; Hexamethonium; Hexamethonium Compounds; In Vitro Tec | 1984 |
Dibenamine enhancement of histamine-induced relaxation of the rabbit mesenteric artery.
Topics: Animals; Cold Temperature; Dibenzylchlorethamine; Dimaprit; Drug Synergism; Histamine; Mesenteric Ar | 1983 |
Vasoactive intestinal polypeptide: increased tone, enhancement of acetylcholine release, and stimulation of adenylate cyclase in intestinal smooth muscle.
Topics: Acetylcholine; Adenylyl Cyclases; Animals; Cyclic GMP; Electric Stimulation; Female; Gastrointestina | 1980 |
Smooth muscle relaxing drugs and guinea pig ileum.
Topics: Acetylcholine; Animals; Barium; Calcium Chloride; Cyclic AMP; Dose-Response Relationship, Drug; Gall | 1981 |
Mechanism of relaxant action of papaverine. Effect on caffeine-induced contraction of guinea pig taenia coli.
Topics: Animals; Bucladesine; Caffeine; Calcium; Colon; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Male; | 1982 |
Similarities between cytomegalovirus-induced cell rounding and contraction of smooth muscle cells.
Topics: Cytomegalovirus; Cytomegalovirus Infections; Cytopathogenic Effect, Viral; Diazoxide; Fibroblasts; H | 1983 |
Norepinephrine-induced contractions of the rat aorta in the absence of extracellular calcium--III. Effects of cyclic nucleotides.
Topics: Animals; Aorta; Bucladesine; Calcium; Culture Media; Cyclic GMP; In Vitro Techniques; Male; Muscle C | 1983 |
Dissociation of phosphorylase a activation and contractile activity in rat portal vein.
Topics: Animals; Calcium; Cyclic AMP; Enzyme Activation; Glycolysis; Isometric Contraction; Isoproterenol; L | 1984 |
Action of papaverine and verapamil on norepinephrine and calcium evoked contraction of vascular and non vascular smooth muscle.
Topics: Animals; Calcium; Female; Male; Muscle Contraction; Muscle, Smooth; Muscle, Smooth, Vascular; Norepi | 1983 |
Prostacyclin-induced contraction of guinea-pig ileum: influence of drugs affecting calcium flux in the smooth muscle.
Topics: Animals; Calcium; Epoprostenol; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contra | 1984 |
Effects of trimebutine maleate (TM-906) on the smooth muscles of isolated guinea pig gallbladder.
Topics: Acetylcholine; Animals; Atropine; Benzoates; Calcium Chloride; Electric Stimulation; Gallbladder; Gu | 1984 |
[Influence of pH changes of the medium on relaxant actions of papaverine].
Topics: Animals; Calcium Channel Blockers; Guinea Pigs; Hydrogen-Ion Concentration; Ileum; In Vitro Techniqu | 1984 |
Antispasmodic effects of an alkaloid extracted from Phyllanthus sellowianus: a comparative study with papaverine.
Topics: Alkaloids; Animals; Brazil; Female; Guinea Pigs; Ileum; Muscle Contraction; Muscle, Smooth; Papaveri | 1984 |
Mechanism of smooth muscle relaxation by rociverine.
Topics: Animals; Atropine; Bridged Bicyclo Compounds; Bridged-Ring Compounds; Calcium; Cyclohexanecarboxylic | 1984 |
Comparison of effects of smooth muscle relaxing drugs in intestinal smooth muscle of guinea pig.
Topics: Animals; Barium; Calcium; Calcium Channel Blockers; Electrophysiology; Guinea Pigs; Histamine; Ileum | 1983 |
On the inhibitory mechanism of bassianolide, a cyclodepsipeptide, in acetylcholine-induced contraction in guinea-pig taenia coli.
Topics: Acetylcholine; Animals; Atropine; Calcium; Colon; Guinea Pigs; Male; Membrane Potentials; Muscle Con | 1983 |
Vascular reactivity in diabetes mellitus: role of the endothelial cell.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Bradykinin; Capillary Permeability; Diabetes Mellitus, Expe | 1983 |
The effect of calcium antagonists on contractions of the sensitized and normal guinea pig ileum.
Topics: Acetylcholine; Animals; Calcium Channel Blockers; Diltiazem; Female; Guinea Pigs; Histamine; Ileum; | 1983 |
[Ba-induced contraction of the guinea pig ileal longitudinal muscle and its inhibition by D-600, benactyzine, and papaverine].
Topics: Animals; Barium; Benactyzine; Calcium; Gallopamil; Guinea Pigs; Ileum; In Vitro Techniques; Muscle C | 1983 |
[Histamine-induced contraction of the guinea pig taenia coli and its inhibition by D-600, papaverine, and benactyzine].
Topics: Animals; Benactyzine; Calcium; Colon; Gallopamil; Guinea Pigs; Histamine; Histamine Antagonists; In | 1983 |
Pharmacological properties of platelet strips.
Topics: Adenosine Diphosphate; Alprostadil; Angiotensin II; Aorta; Blood Platelets; Humans; In Vitro Techniq | 1983 |
Inhibition by papaverine of calcium movements and tension in the smooth muscles of rat vas deferens and urinary bladder.
Topics: Animals; Calcium; Dose-Response Relationship, Drug; Male; Microsomes; Mitochondria, Muscle; Muscle C | 1984 |
Effects of trimebutine maleate (TM-906) on the spontaneous contraction of isolated guinea pig colon.
Topics: Animals; Atropine; Benzoates; Calcium Chloride; Colon; Diltiazem; Gastrointestinal Motility; Guinea | 1984 |
New morphological evidence for a mechanism of lymph formation in skeletal muscle.
Topics: Animals; Female; Lymphatic System; Male; Microscopy, Electron; Muscle Contraction; Muscles; Norepine | 1984 |
Regulation of muscarinic acetylcholine receptors and contractility of guinea pig vas deferens.
Topics: Acetylcholine; Animals; Colchicine; Dibenzylchlorethamine; Dose-Response Relationship, Drug; Egtazic | 1981 |
Actions and interactions of ergotamine and dihydroergocristine in rat aortic strips.
Topics: Animals; Aorta, Thoracic; Dihydroergotoxine; Drug Interactions; Ergotamine; In Vitro Techniques; Mal | 1981 |
A comparison of the differential effects of nitroglycerin, nifedipine and papaverine on contractures induced in vascular and intestinal smooth muscle by potassium and lanthanum.
Topics: Animals; Calcium; Coronary Vessels; Dogs; Female; Intestines; Lanthanum; Male; Muscle Contraction; M | 1981 |
Effects of an extract of Ginkgo biloba and diverse substances on the phasic and tonic components of the contraction of an isolated rabbit aorta.
Topics: Animals; Calcium; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth, Vascula | 1983 |
The effects of papaverine on the electrical and mechanical activity of the guinea-pig ureter.
Topics: Action Potentials; Animals; Electric Conductivity; Guinea Pigs; In Vitro Techniques; Manganese; Memb | 1983 |
Mechanism of relaxant action of papaverine. II. Differences between modes of relaxant effects of papaverine and amytal in guinea-pig taenia coli.
Topics: Amobarbital; Animals; Calcium; Calcium Radioisotopes; Guinea Pigs; In Vitro Techniques; Male; Muscle | 1983 |
Characterization of norepinephrine-induced contractile response in isolated rabbit basilar artery.
Topics: Animals; Basilar Artery; Calcium; Gallopamil; In Vitro Techniques; Male; Muscle Contraction; Muscle, | 1983 |
[Model for the study of the properties of the smooth muscle of granulation tissue].
Topics: Animals; Croton Oil; Granulation Tissue; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smoo | 1981 |
Relaxation of carbocyclic thromboxane A2-induced contractions of isolated coronary arteries by nifedipine.
Topics: Animals; Cats; Coronary Vessels; Dimethyl Sulfoxide; In Vitro Techniques; Male; Muscle Contraction; | 1982 |
Mechanical properties of arteries.
Topics: Animals; Aorta, Abdominal; Arteries; Biomechanical Phenomena; Carotid Arteries; Elasticity; Female; | 1982 |
Antispasmodic effects of valeriana compounds: an in-vivo and in-vitro study on the guinea-pig ileum.
Topics: Animals; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Papaverine; Pa | 1982 |
[Effects of trimebutine maleate (TM-906) on the spontaneous contraction of the isolated guinea pig stomach].
Topics: Animals; Atropine; Benzoates; Calcium; Diltiazem; Dose-Response Relationship, Drug; Guinea Pigs; In | 1982 |
Dependence of elastic and viscous properties of elastic arteries on circumferential wall stress at two different smooth muscle tones.
Topics: Animals; Arteries; Elasticity; Female; In Vitro Techniques; Muscle Contraction; Muscle Relaxation; M | 1981 |
Papaverine-insensitive and papaverine-sensitive drug-induced contractions of chick smooth muscle.
Topics: Animals; Calcium; Chickens; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Papaverine; Rec | 1981 |
Mechanism of electrical stimulation-induced subsensitivity of vascular smooth muscle.
Topics: Animals; Arteries; Calcium; Electric Stimulation; Female; In Vitro Techniques; Male; Muscle Contract | 1981 |
Vein contraction and smooth muscle cell extensions as causes of endothelial damage during graft preparation.
Topics: Animals; Bioprosthesis; Blood; Blood Vessel Prosthesis; Dogs; Endothelium; Female; Heparin; Isotonic | 1981 |
Quantitization of Ca spike frequency in a single sucrose gap and mechanical relaxation induced by Ca antagonists, isoproterenol and papaverine.
Topics: Action Potentials; Calcium; Calcium Channel Blockers; Humans; In Vitro Techniques; Isoproterenol; Ma | 1981 |
Effect of histamine on the gastric smooth muscles of guinea pig.
Topics: Acetylcholine; Animals; Cimetidine; Guinea Pigs; Histamine; Male; Muscle Contraction; Muscle, Smooth | 1981 |
Paradoxical relaxation of arterial strips induced by vasoconstrictive agents.
Topics: Adenosine; Angiotensin II; Animals; Bradykinin; Dogs; Dopamine; Dose-Response Relationship, Drug; Fe | 1980 |
[Potentiation of the effect of selected isoquinoline derivatives on the activity of intestinal smooth muscle in vitro].
Topics: Animals; Drug Synergism; Female; Guinea Pigs; In Vitro Techniques; Intestine, Small; Isoquinolines; | 1980 |
Spasmogenic effects of L-ascorbic acid on the guinea pig isolated ileum preparation.
Topics: Adenosine; Animals; Ascorbic Acid; Atropine; Calcium; Dose-Response Relationship, Drug; Glucose; Gui | 1980 |
A newly isolated antispasmodic--butylidenephthalide.
Topics: Acetylcholine; Animals; Barium; Calcium; Colon; Guinea Pigs; Ileum; In Vitro Techniques; Male; Medic | 1980 |
A calcium reversal phenomenon: differentiation of excitatory and inhibitory roles of Ca in uterine smooth muscle contraction.
Topics: Animals; Calcium; Female; Gallopamil; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Oxyto | 1980 |
Effects of prostaglandin E1, and papaverine on non-neurogenic and neurogenic contraction of the isolated rabbit erectile tissue.
Topics: Alprostadil; Animals; Dose-Response Relationship, Drug; Ethylmaleimide; Male; Muscle Contraction; Mu | 1995 |
Effect of endothelium on diabetes-induced changes in constrictor responses mediated by 5-hydroxytryptamine in rat aorta.
Topics: Amphetamines; Animals; Aorta; Arginine; Body Weight; Diabetes Mellitus, Experimental; Endothelium; I | 1993 |
Smooth muscle contractility in prostatic hyperplasia: role of cyclic adenosine monophosphate.
Topics: Bucladesine; Colforsin; Cyclic AMP; Dose-Response Relationship, Drug; Humans; Male; Milrinone; Muscl | 1994 |
Collagenase increases shortening of human bronchial smooth muscle in vitro.
Topics: Acetylcholine; Aged; Biomechanical Phenomena; Bronchi; Clostridium; Female; Histamine; Humans; In Vi | 1995 |
A possible approach to the suppression of side effects induced by PGE1.
Topics: Alprostadil; Animals; Atropine; Capillary Permeability; Gabexate; Guanidines; Guinea Pigs; Histamine | 1995 |
Porcine detrusor cyclic nucleotide phosphodiesterase isoenzymes: characterization and functional effects of various phosphodiesterase inhibitors in vitro.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Calmodulin; Carba | 1995 |
Angioplasty reduces pharmacologically mediated vasoconstriction in rabbit carotid arteries with and without vasospasm.
Topics: Acetylcholine; Analysis of Variance; Angioplasty; Animals; Carotid Arteries; In Vitro Techniques; Is | 1995 |
Endothelium-dependent relaxation resistant to NG-nitro-L-arginine in rat aorta.
Topics: Acetylcholine; Analysis of Variance; Animals; Aorta, Thoracic; Arginine; Atropine; Biological Factor | 1995 |
Characterization and function of histamine receptors in corpus cavernosum.
Topics: Acetylcholine; Animals; Cimetidine; Dimaprit; Dose-Response Relationship, Drug; Electric Stimulation | 1995 |
Mechanism of the cardiovascular activity of laudanosine: comparison with papaverine and other benzylisoquinolines.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; Calcium; Cattle; Decerebrate State; Hemodynamics; In | 1994 |
Evidence that depletion of internal calcium stores sensitive to noradrenaline elicits a contractile response dependent on extracellular calcium in rat aorta.
Topics: Adrenergic alpha-Antagonists; Animals; Aorta, Thoracic; Caffeine; Calcium; Extracellular Space; In V | 1993 |
Different pharmacological characteristics of structurally similar benzylisoquinoline analogs, papaverine, higenamine, and GS 389, on isolated rat aorta and heart.
Topics: Adrenergic beta-Agonists; Alkaloids; Animals; Aorta, Thoracic; Calcium Channels; Cyclic AMP; Electri | 1994 |
Effects of papaverine and prostaglandin E1 on corpus cavernosum smooth muscle of arteriogenically and diabetically impotent men.
Topics: Alprostadil; Diabetic Angiopathies; Dose-Response Relationship, Drug; Humans; Impotence, Vasculogeni | 1994 |
Physiological assessment of augmented vascularity induced by VEGF in ischemic rabbit hindlimb.
Topics: Animals; Coronary Angiography; Dose-Response Relationship, Drug; Endothelial Growth Factors; Femoral | 1994 |
Relationship between cytosolic calcium concentration and force in the papaverine-induced relaxation of medial strips of pig coronary artery.
Topics: Animals; Caffeine; Calcium; Coronary Vessels; Cytosol; Female; Fluorescent Dyes; Fura-2; Histamine; | 1994 |
Effects of okadaic acid on the human isolated bronchus.
Topics: Acetylcholine; Bronchi; Cadmium; Cadmium Compounds; Caffeine; Dose-Response Relationship, Drug; Ethe | 1994 |
Activation of the non-actomyosin component of aortic wall contraction by phorbol ester.
Topics: Actomyosin; Animals; Aorta, Thoracic; Egtazic Acid; Guinea Pigs; In Vitro Techniques; Muscle Contrac | 1994 |
Effect of mode of application of papaverine on the contractile response of the internal mammary artery.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Aged; Dopamine; Dose-Resp | 1994 |
Inhibitory effects of cicletanine on smooth muscle in comparison to those of nifedipine and sodium nitroprusside.
Topics: Animals; Anti-Arrhythmia Agents; Cyclic GMP; Female; Guinea Pigs; In Vitro Techniques; Male; Muscle | 1993 |
The role of active smooth-muscle contraction in the occurrence of chronic vasospasm in the canine two-hemorrhage model.
Topics: 1-(5-Isoquinolinesulfonyl)-2-Methylpiperazine; Animals; Basilar Artery; Dogs; Female; Ischemic Attac | 1994 |
[Supra-systolic elevation of the intra-cavernous pressure secondary to stimulation of the glans penis].
Topics: Adult; Blood Pressure; Electric Stimulation; Electromyography; Humans; Male; Middle Aged; Muscle Con | 1993 |
[Pharmacological studies on antidiarrheal effects of berberine and geranii herba].
Topics: Acetylcholine; Animals; Antidiarrheals; Atropine; Berberine; Guinea Pigs; In Vitro Techniques; Intes | 1993 |
Antispasmodic activity of benzylisoquinoline alkaloids analogous to papaverine.
Topics: Alkaloids; Animals; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Papaverine; Parasympath | 1993 |
Phosphodiesterase isoenzymes in human ureteral smooth muscle: identification, characterization, and functional effects of various phosphodiesterase inhibitors in vitro.
Topics: Chromatography, Ion Exchange; Cyclic AMP; Cyclic GMP; Dose-Response Relationship, Drug; Humans; Hydr | 1995 |
Actions of galanin and some of its analogues on rat isolated gastric fundus.
Topics: Analysis of Variance; Animals; Bucladesine; Calcium Channel Blockers; Dibenzylchlorethamine; Diltiaz | 1996 |
The increase in cyclic nucleotide level decreases the contractile response of gastric smooth muscle strips to galanin.
Topics: Animals; Bucladesine; Cyclic AMP; Galanin; Gastric Fundus; In Vitro Techniques; Muscle Contraction; | 1996 |
Relationships between structure and vascular activity in a series of benzylisoquinolines.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Aorta; Diltiazem; Female; In Vitro Techniques; Inosito | 1997 |
DMPP causes relaxation of rat distal colon by a purinergic and a nitrergic mechanism.
Topics: Adenosine Triphosphate; Anesthetics, Local; Animals; Carbachol; Colon; Dimethylphenylpiperazinium Io | 1997 |
The 5-HT and alpha-adrenoceptor antagonist effect of four benzylisoquinoline alkaloids on rat aorta.
Topics: Adrenergic alpha-Antagonists; Alkaloids; Animals; Aorta, Thoracic; Apomorphine; Aporphines; Benzylis | 1998 |
Neurogenic contraction and relaxation of human penile deep dorsal vein.
Topics: Acetylcholine; Adolescent; Adult; Aged; Electric Stimulation; Endothelium, Vascular; Humans; In Vitr | 1998 |
Caverno-occlusive and autonomic dysfunction: a new concept in young patients.
Topics: Adult; Biomarkers; Electromyography; Erectile Dysfunction; Humans; Male; Muscle Contraction; Muscle, | 1998 |
The difference in the inhibitory mechanisms of papaverine on vascular and intestinal smooth muscles.
Topics: Animals; Aorta; Calcium; Cyclic AMP; Cyclic GMP; Flavoproteins; Ileum; In Vitro Techniques; Male; Mi | 1998 |
Effect of calcium antagonists on the response to noradrenaline in the whole and bisected rat vas deferens.
Topics: Animals; Calcium Channel Blockers; Cromakalim; Diltiazem; Flunarizine; Male; Muscle Contraction; Mus | 1998 |
Endothelin-1 affects capsaicin-evoked release of neuropeptides from rat vas deferens.
Topics: Animals; Bronchodilator Agents; Calcitonin Gene-Related Peptide; Capsaicin; Dose-Response Relationsh | 1999 |
Effects of chronic unilateral internal pudendal arterial occlusion on reactivity of isolated corpus cavernosum strips from rabbits.
Topics: Adenosine; Animals; Arterial Occlusive Diseases; Arteries; Carbachol; Chronic Disease; Dose-Response | 1999 |
Responses of group III and IV muscle afferents to distension of the peripheral vascular bed.
Topics: Animals; Cats; Electric Stimulation; Female; Hindlimb; Isoproterenol; Male; Muscle Contraction; Musc | 1999 |
Abanoquil, a new alpha-1 adrenoceptor antagonist. In vitro and in vivo effect on erectile tissue.
Topics: Adrenergic alpha-Antagonists; Aminoquinolines; Animals; Macaca fascicularis; Male; Muscle Contractio | 2000 |
Sildenafil citrate on nitrergic transmission in anococcygeus muscles from the urogenital system of male and female mice.
Topics: Animals; Carbachol; Colforsin; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Male; | 2000 |
Oxidized LDL increases the sensitivity of the contractile apparatus in isolated resistance arteries for Ca(2+) via a rho- and rho kinase-dependent mechanism.
Topics: Acetylcholine; Animals; Arteries; Calcium; Cricetinae; Endothelins; Intracellular Signaling Peptides | 2000 |
Augmented acetylcholine-induced translocation of RhoA in bronchial smooth muscle from antigen-induced airway hyperresponsive rats.
Topics: Acetylcholine; Amides; Animals; Antigens; Biological Transport; Bronchi; Bronchial Hyperreactivity; | 2001 |
Systemic and topical drug administration in the pig ureter: effect of phosphodiesterase inhibitors alpha1, beta and beta2-adrenergic receptor agonists and antagonists on the frequency and amplitude of ureteral contractions.
Topics: Administration, Topical; Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Adrenergic beta-Ag | 2001 |
Relaxing effects of Ligstrum purpurascens extract and purified acteoside in rat aortic rings.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Acetylcholine; Animals; Aorta, T | 2001 |
Role of endogenous nitric oxide generation in the regulation of vascular tone and reactivity in small vessels as investigated in transgenic mice using synchrotron radiation microangiography.
Topics: Angiography; Animals; Cattle; Enzyme Inhibitors; Hindlimb; In Vitro Techniques; Lipopolysaccharides; | 2001 |
Quantitative analysis of papaverine-mediated blood-brain barrier disruption in rats.
Topics: Animals; Blood-Brain Barrier; Brain; Dose-Response Relationship, Drug; Male; Muscle Contraction; Mus | 2001 |
Experimental stereotactic gamma knife radiosurgery. Vascular contractility studies of the rat middle cerebral artery after chronic survival.
Topics: Animals; Arginine; Dinoprost; Disease Models, Animal; Dose-Response Relationship, Drug; Histamine; I | 2002 |
Muscle relaxing activity of Hyssopus officinalis essential oil on isolated intestinal preparations.
Topics: Acetylcholine; Animals; Barium Compounds; Bicyclic Monoterpenes; Bridged Bicyclo Compounds; Calcium | 2002 |
Characterization of small arteries isolated from the human placental chorionic plate.
Topics: 15-Hydroxy-11 alpha,9 alpha-(epoxymethano)prosta-5,13-dienoic Acid; Adult; Arteries; Chorionic Villi | 2002 |
Action of six commonly used benzodiazepines on isolated guinea-pig ileum preparation.
Topics: Animals; Anti-Anxiety Agents; Barium; Benzodiazepines; Carbachol; Guinea Pigs; Ileum; In Vitro Techn | 1975 |
[Effect of atropine sulfate, papaverin HC1 and antihistaminic preparations on isolated organs of various experimental animals].
Topics: Animals; Atropine; Guinea Pigs; Histamine H1 Antagonists; Hydrochloric Acid; In Vitro Techniques; Mu | 1975 |
Effect of beta-adrenoceptor stimulators, papaverine and theophylline on guinea-pig trachea contracted by different drugs.
Topics: Adrenergic beta-Agonists; Animals; Drug Interactions; Guinea Pigs; Histamine; Imidazoles; Isoprotere | 1976 |
Some aspects in the pharmacology of diclonium bromide (2-(3,2-dichloroanilino)quinolizinium bromide). Part I: Antispasmodic action.
Topics: Acetylcholine; Animals; Colon; Dogs; Duodenum; Electric Stimulation; Gastrointestinal Motility; Guin | 1976 |
[Action mechanisms of the contracting drugs, K, acetylcholine, histamine and Ba and of the antispasmodics, isoproterenol and papaverine in the isolated guinea pig ileum, particularly in relation to Ca].
Topics: Acetylcholine; Animals; Barium; Calcium; Dinitrophenols; Dose-Response Relationship, Drug; Guinea Pi | 1976 |
Specific enhancement of norepinephrine-induced contraction in rat veins after beta adrenergic antagonists.
Topics: Adrenergic beta-Antagonists; Animals; Drug Interactions; Electric Stimulation; In Vitro Techniques; | 1977 |
Calcium ions and relaxation of intestinal smooth muscle induced by papaverine and aspaminol.
Topics: Animals; Calcium; Colon; Guinea Pigs; Ileum; In Vitro Techniques; Ions; Male; Microsomes; Muscle Con | 1977 |
Sensitization of contracted tracheal smooth muscle to beta-adrenergic spasmolysis by subthreshold doses of papaverine.
Topics: Adrenergic beta-Agonists; Animals; Drug Synergism; Guinea Pigs; Methacholine Compounds; Models, Biol | 1977 |
The inhibitory effect of papaverine on respiration-dependent contracture of guinea pig taenia coli in high-K medium. I. The relationship between contracture and respiration.
Topics: Animals; Calcium; Guinea Pigs; Hydrogen-Ion Concentration; Imidazoles; In Vitro Techniques; Male; Mu | 1977 |
Relaxation of depolarized guinea pig taenia caecum induced by some antispasmodics.
Topics: Animals; Benactyzine; Bucladesine; Calcium; Cecum; Cyclic AMP; Guinea Pigs; In Vitro Techniques; Iso | 1978 |
Nonspecific relaxation of intestinal smooth muscle induced by antispasmodics and movement of Calcium ions.
Topics: Animals; Benactyzine; Calcium; Colon; Histamine H1 Antagonists; In Vitro Techniques; Ions; Male; Mic | 1978 |
Transient responses of rabbit cerebral blood vessels to norepinephrine: correlation with intrinsic myogenic tone.
Topics: Adrenergic alpha-Antagonists; Animals; Basilar Artery; Carotid Artery, Internal; Cerebral Arteries; | 1979 |
Spasmolytic constituents of Cedrus deodara (Roxb.) Loud: pharmacological evaluation of himachalol.
Topics: Animals; Benzocycloheptenes; Blood Circulation; Blood Pressure; Bronchi; Cattle; Charcoal; Dose-Resp | 1975 |
Effect of the ionophore, A23187, on contraction and relaxation of rat arteries and veins.
Topics: Animals; Anti-Bacterial Agents; Arteries; Blood Vessels; Calcimycin; Calcium; In Vitro Techniques; M | 1978 |
Difference between inhibitory actions of papaverine and dehydroepiandrosterone on the isolated guinea-pig ileum.
Topics: Acetylcholine; Aminophylline; Animals; Cyanides; Dehydroepiandrosterone; Depression, Chemical; Dose- | 1975 |
Effect of papaverine on the longitudinal and circular smooth muscle of the guinea-pig caecum.
Topics: Animals; Calcium; Cecum; Extracellular Space; Guinea Pigs; Male; Muscle Contraction; Muscle, Smooth; | 1976 |
[Strict additivity of the antispasmodic effects of papaverine and tiemonium: an example of sequential blockage].
Topics: Acetylcholine; Animals; Barium; Female; Guinea Pigs; Histamine Antagonists; Ileum; Jejunum; Kinetics | 1977 |
Papaverine, cyclic AMP and the dependence of the rat aorta on extracellular calcium.
Topics: Animals; Aorta, Thoracic; Bucladesine; Calcium; Depression, Chemical; In Vitro Techniques; Male; Mus | 1975 |
Antiphosphodiesterase activity and nonspecific smooth muscle relaxation tested on intestinal smooth muscles.
Topics: Animals; Cecum; Cyclic AMP; Dogs; Guinea Pigs; In Vitro Techniques; Intestines; Kinetics; Male; Musc | 1975 |
Levels of cyclic AMP and electrical events during inhibition of contractile activity in vascular smooth muscle.
Topics: Animals; Cyclic AMP; Depression, Chemical; Electric Stimulation; Isoproterenol; Male; Muscle Contrac | 1975 |
[The mechanism of action of bencyclane on smooth musculature].
Topics: Aminophylline; Animals; Bencyclane; Cattle; Coronary Vessels; Cyclic AMP; Cycloheptanes; In Vitro Te | 1975 |
[The action mechanism of trapidil (Rocornal)].
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Arteries; Blood Pressure; Guinea Pigs; Heart; In Vitro | 1975 |
Differentiation of intestinal smooth muscle relaxation caused by drugs that inhibit phosphodiesterase.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Aminophylline; Ammonium Chloride; Animals; Calcium; Carbachol; | 1976 |
Drug-induced smooth muscle contraction with no change in the level of cyclic GMP.
Topics: Animals; Cyclic GMP; Duodenum; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; Papave | 1976 |
Influence of papaverine derivatives on phosphodiesterase activity, cyclic 3',5'-AMP levels and relaxing effect on rabbit ileum.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Bucladesine; Cyclic AMP; Female; Ileum; Kinetics; Male | 1976 |
Cyclic 3',5'-adenosine monophosphate and bronchial tone.
Topics: Adenylyl Cyclases; Animals; Bronchi; Cyclic AMP; Dogs; Epinephrine; Female; In Vitro Techniques; Iso | 1977 |
Effect of isoprenaline and phenylephrine on the adenosine 3',5'-monophosphate content and mechanical activity of cold-stored and fresh taenia caecum from the guinea-pig.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenylyl Cyclases; Animals; Catecholamines; Cecum; Cold Tempera | 1977 |
Depressive effect of epinephrine mediated via adrenergic beta-receptor in isolated rat colon and duodenum.
Topics: Acetylcholine; Animals; Bucladesine; Colon; Depression, Chemical; Duodenum; Epinephrine; In Vitro Te | 1977 |
[Contractile responses of the guinea pig ileal longitudinal muscle to antispasmodics (author's transl)].
Topics: Acetylcholine; Animals; Benactyzine; Calcium; Cyclic GMP; Drug Synergism; Gallopamil; Guinea Pigs; I | 1977 |
Modes of vasoconstrictor and vasodilator neurotransmission.
Topics: Adenosine Triphosphate; Adrenergic Fibers; Animals; Electric Stimulation; Muscle Contraction; Muscle | 1978 |
[Effects of smooth muscle relaxants on contracting reactions caused by K,ACh, and Ba].
Topics: Acetylcholine; Animals; Barium; Bucladesine; Guinea Pigs; In Vitro Techniques; Male; Metaproterenol; | 1977 |
Beta-adrenoceptor stimulation and cyclic AMP levels in bovine tracheal muscle of old and young animals.
Topics: Acetylcholine; Age Factors; Animals; Carbachol; Cattle; Cyclic AMP; Histamine; Isoproterenol; Muscle | 1978 |
Cyclic AMP in the rat jugular vein: relationship to vascular relaxation.
Topics: Animals; Cyclic AMP; Isoproterenol; Jugular Veins; Male; Muscle Contraction; Muscle Relaxation; Musc | 1979 |
[Action mechanism of vascular spasmolytics. 5. Drug-related relaxation and adenosine-3',5'-monophosphate content of isolated coronary arteries under conditions of fluoride-induced contracture].
Topics: Adenosine; Animals; Calcium; Cattle; Coronary Vessels; Cyclic AMP; Fluorides; Isoproterenol; Muscle | 1979 |
On the mechanism of relaxation of tracheal muscle by theophylline and other cyclic nucleotide phosphodiesterase inhibitors.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenosine; Animals; Cyclic AMP; Cyclic GMP; Drug Interactions; | 1979 |
The treatment of threatened premature labor by tocolytics, Ca++-Antagonists and anti-inflammatory drugs.
Topics: Adrenergic beta-Agonists; Animals; Anti-Inflammatory Agents; Aspirin; Calcium; Drug Therapy, Combina | 1975 |
Relationships between Ca2+ uptake by a microsomal fraction of guinea-pig taenia caecum and its relaxation.
Topics: Adenosine Triphosphate; Animals; Calcium; Calcium Radioisotopes; Cecum; Cyclic AMP; Dose-Response Re | 1975 |
Proceedings: Experiments to classify the beta-receptor-stimulating properties of tetrahydropapaveroline.
Topics: Adrenergic beta-Agonists; Animals; Cats; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Papav | 1975 |
On the use of functional antagonism to estimate dissociation constants for beta adrenergic receptor agonists in isolated guinea-pig trachea.
Topics: Adrenergic beta-Agonists; Animals; Carbachol; Dose-Response Relationship, Drug; Ethanolamines; Femal | 1975 |
The effect of potassium on frog stomach muscle.
Topics: Animals; Anura; Biological Transport, Active; Muscle Contraction; Muscle Relaxation; Ouabain; Papave | 1979 |
Changes in muscarinic acetylcholine receptors of mice by chronic administrations of diisopropylfluorophosphate and papaverine.
Topics: Animals; Brain; Dose-Response Relationship, Drug; Intestine, Small; Isoflurophate; Kinetics; Male; M | 1979 |
[Comparative analysis of the action of papaverine, novodrin, La3+ and compound D-600 on the guinea pig tenia coli depolarized smooth muscle].
Topics: Animals; Calcium; Colon; Gallopamil; Guinea Pigs; Histamine; History, 20th Century; In Vitro Techniq | 1979 |
Effects of prostaglandin E1 on isolated dog renal artery.
Topics: Animals; Diltiazem; Dogs; Dose-Response Relationship, Drug; Female; In Vitro Techniques; Isoproteren | 1979 |
Post-tetanic potentiation in the innervated smooth muscle preparation of the guinea-pig ileum.
Topics: Acetylcholine; Animals; Guinea Pigs; Ileum; Indomethacin; Male; Muscle Contraction; Muscle, Smooth; | 1979 |
Screening pharmacological studies of four dihydroisoquinoline derivatives.
Topics: Analgesics; Animals; Behavior, Animal; Blood Pressure; Cats; Drug Evaluation, Preclinical; Guinea Pi | 1979 |
Mechanism of action of bradykinin-induced release of prostaglandin E.
Topics: Animals; Arachidonic Acids; Bradykinin; Ear; Female; In Vitro Techniques; Male; Muscle Contraction; | 1977 |
The influence of vasoactive substances on blood flow and contractile responses of cat gastrocnemius.
Topics: Acetylcholine; Angiotensin II; Animals; Blood Circulation; Bradykinin; Cats; Dose-Response Relations | 1977 |
The inhibitory effect of papaverine on respiration-dependent contracture of guinea pig taenia coli in high-K medium. III. The differential effect of papaverine and rotenone on DT diaphorase.
Topics: Animals; Colon; Guinea Pigs; In Vitro Techniques; Mitochondria; Muscle Contraction; Muscle, Smooth; | 1977 |
Correlation between the hydrolysis constants and spasmolytic activities of some isoquinolines.
Topics: Animals; Chemistry, Pharmaceutical; Guinea Pigs; Hydrolysis; In Vitro Techniques; Isoquinolines; Mus | 1977 |
[Non-specific relaxation of the smooth muscle caused by drugs].
Topics: Animals; Benactyzine; In Vitro Techniques; Male; Muscle Contraction; Muscle Relaxation; Muscle, Smoo | 1977 |
Modification of the antispasmodic actions of isoproterenol and papaverine by removal of external Na in the isolated rat rectum.
Topics: Animals; In Vitro Techniques; Isoproterenol; Male; Muscle Contraction; Muscle Relaxation; Muscle, Sm | 1977 |
A tonic component in the motility of the upper urinary tract (renal pelvis-ureter).
Topics: Animals; Epinephrine; Kidney Pelvis; Muscle Contraction; Nifedipine; Nitroprusside; Papaverine; Pyri | 1978 |
[Effect of papaverine on the tonus and contraction of depolarized taenia coli musculature in guinea pigs].
Topics: Animals; Calcium; Cell Membrane Permeability; Colon; Drug Interactions; Guinea Pigs; Histamine; Musc | 1978 |
Acute myocardial ischaemia in anaesthetized cats: effects of papaverine.
Topics: Animals; Cats; Coronary Circulation; Coronary Disease; Coronary Vessels; Electrocardiography; Muscle | 1978 |
Comparison of the action of cinnarizine and papaverine.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Calcium Chloride; Cinnarizine; In Vitro Techniques; Mesente | 1978 |
A new bioassay for glucagon.
Topics: Animals; Biological Assay; Chick Embryo; Drug Synergism; Glucagon; Guinea Pigs; In Vitro Techniques; | 1978 |
[Kinetics of guinea pig taenia coli smooth muscle relaxation. Effect of papaverine and polarization].
Topics: Animals; Calcium; Colon; Electric Stimulation; Guinea Pigs; In Vitro Techniques; Ion Channels; Muscl | 1978 |
Contractile activity and reactivity to acetylcholine and adrenaline of smooth muscle strips from crop, postcrop oesophagus and glandular stomach in some birds.
Topics: Acetylcholine; Animals; Birds; Chickens; Crop, Avian; Epinephrine; Esophagus; In Vitro Techniques; M | 1978 |
[Papaverine actions and mechanism of vascular muscle relaxation (author's transl)].
Topics: Aged; Animals; Calcium; Dogs; Humans; Muscle Contraction; Muscle Relaxation; Muscle, Smooth; Papaver | 1978 |
[Diphasic course of the curve of contraction of isolated intestine produced by massive doses of drugs. I. Effect of calcium].
Topics: Acetylcholine; Animals; Calcium; Carbachol; Dose-Response Relationship, Drug; Guinea Pigs; Histamine | 1978 |
Alternative mechanisms for the potentiation of the relaxation evoked by isoprenaline in aortae from young and aged rats.
Topics: Aging; Animals; Aorta, Thoracic; Blood Vessels; Cinnarizine; Drug Synergism; Isoproterenol; Muscle C | 1979 |
A comparison of the inhibitory effect of cinnarizine and papaverine on the noradrenaline- and calcium-evoked contraction of isolated rabbit aorta and mesenteric arteries.
Topics: Animals; Aorta, Thoracic; Blood Vessels; Calcium; Cinnarizine; In Vitro Techniques; Mesenteric Arter | 1979 |
Comparison of drug-induced responses of rabbit trachea and bronchus.
Topics: Aminophylline; Animals; Atropine; Bronchi; Carbachol; Dose-Response Relationship, Drug; Female; Hist | 1976 |
The role of prostaglandins in the spontaneous motility of the fallopian tube.
Topics: Fallopian Tubes; Female; Humans; In Vitro Techniques; Indomethacin; Menstruation; Muscle Contraction | 1977 |
Effects of hexoestrol on the contractility of the isolated, blood-perfused canine papillary muscle and of the guinea-pig ileum.
Topics: Acetylcholine; Animals; Atropine; Barium; Coronary Circulation; Diphenhydramine; Dogs; Female; Hexes | 1977 |
Effects of phospholipase C on the electrical and mechanical activity of guinea pig taenia coli.
Topics: Acetylcholine; Animals; Atropine; Barium; Calcium; Colon; Guinea Pigs; Hexamethonium Compounds; In V | 1977 |
Inhibition by Cd2+ verapamil and papaverine of Ca2+-induced contractions in isolated cerebral and peripheral arteries of the dog.
Topics: Animals; Blood Vessels; Cadmium; Calcium; Cerebral Arteries; Coronary Vessels; Dogs; Female; In Vitr | 1977 |
Influence of moderate vasoconstriction on the wave reflection properties of the pulmonary arterial bed.
Topics: Acetylcholine; Animals; Blood Pressure; Muscle Contraction; Papaverine; Pressure; Pulmonary Artery; | 1976 |
[Antispasmodic mechanisms of actions of isoproterenol and papaverine with special reference to their relation to Ca (experiments using the isolated rat rectum)].
Topics: Acetylcholine; Animals; Calcium; Dose-Response Relationship, Drug; In Vitro Techniques; Isoprotereno | 1976 |
[Influence of removal of Na from the bath solution on the antispasmodic actions of isoproterenol and papaverine, with special reference to their relations to Ca (experiments using the isolated rat rectum)].
Topics: Acetylcholine; Animals; Calcium; Dose-Response Relationship, Drug; In Vitro Techniques; Isoprotereno | 1976 |
Relaxation of isolated rabbit arteries by fusaric (5-butylpicolinic) acid.
Topics: Aminophylline; Angiotensin II; Animals; Arteries; Atropine; Calcium; Catecholamines; Female; Fusaric | 1976 |
Pharmacological effect on the average rates of development of the contractile and relaxation phases of the acetylcholine contractile effect in the smooth muscles of guinea-pig caecum.
Topics: Acetylcholine; Animals; Barium; Cecum; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; M | 1976 |
[Effects of viquidil on the electric and mechanical activity of smooth muscle].
Topics: Action Potentials; Animals; Guinea Pigs; Muscle Contraction; Muscle, Smooth; Papaverine; Quinolines | 1976 |
Antagonism of the uterotonic action of oxytocin in vitro.
Topics: Albuterol; Animals; Drug Interactions; Drug Synergism; Epinephrine; Female; In Vitro Techniques; Iso | 1975 |
Effects of L-dopa metabolites at a dopamine receptor suggest a basis for 'on-off' effect in Parkinson's disease.
Topics: Animals; Dopamine; Dopamine Antagonists; Evoked Potentials; Intestinal Mucosa; Isoquinolines; Levodo | 1975 |
Comparative actions of the trimetoquinol, tetrahydropapaveroline and salsolinol isomers in beta-adrenoceptor systems.
Topics: Alkaloids; Animals; Dose-Response Relationship, Drug; Female; Guinea Pigs; Heart Atria; Isoprotereno | 1975 |
Contraction and relaxation of vascular smooth muscle and calcium, strontium, barium.
Topics: Animals; Barium; Blood Vessels; Calcium; Cations, Divalent; Dogs; In Vitro Techniques; Isoproterenol | 1975 |
[Action on the isolated guinea-pig ileum and toxicity of some derivatives of 1,5-bis-(3,4-methylendioxyphenyl)-n. pentane].
Topics: Amines; Animals; Butylamines; Dioxoles; Guinea Pigs; Ileum; Muscle Contraction; Muscle, Smooth; Papa | 1975 |
Influence of papaverine, D600, and nifedipine on the effects of noradrenaline and calcium on the isolated aorta and mesenteric artery of the rabbit.
Topics: Animals; Anti-Arrhythmia Agents; Aorta, Thoracic; Calcium; Calcium Chloride; Dose-Response Relations | 1975 |
[Pharmacological action of cattle prostate extracts (PE). V. Effect on the bladder].
Topics: Acetylcholine; Animals; Barium; Blood Pressure; Cattle; Dogs; Guinea Pigs; Histamine; Ileum; In Vitr | 1975 |
2-(3,4-Dichloroanilino)quinolizinium bromide, a unique antispasmodic, antisecretory, and antiulcerogenic agent.
Topics: Animals; Atropine; Colon; Depression, Chemical; Dogs; Gastric Juice; Gastrointestinal Agents; Ligati | 1975 |
Effects of temperature and spasmolytic agents on the rate of relaxation of intestinal smooth muscle.
Topics: Aminophylline; Animals; Calcium; Cytoplasm; Gallopamil; In Vitro Techniques; Intestines; Manganese; | 1975 |
Reduction of the tone of the isolated human umbilical artery by indomethacin, eicosa-5,8,11,14-tetraynoic acid and polyphloretin phosphate.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Depression, Chemical; Dose-Response Relationship, Drug; Drug Intera | 1975 |
Different responses to prostaglandins E1 and E2 of isolated canine coronary arteries.
Topics: Animals; Coronary Vessels; Dogs; Dose-Response Relationship, Drug; Muscle Contraction; Papaverine; P | 1975 |
[Proceedings: Effects of papaverine on caffeine-induced contraction of the smooth muscle].
Topics: Animals; Caffeine; Guinea Pigs; In Vitro Techniques; Muscle Contraction; Muscle, Smooth; Papaverine | 1975 |
[Effects of 1, 4-bis-(3-(3, 4, 5-trimethoxy benzoyl oxy)-propyl) perhydro-1, 4-diazepine (dilazep) on the isolated smooth muscles].
Topics: Adenine Nucleotides; Adenosine; Animals; Aorta; Calcium; Dilazep; Dogs; Dose-Response Relationship, | 1975 |
Effects of propiverine hydrochloride on the spontaneous contractions of isolated guinea-pig urinary bladder strip and rhythmic urinary bladder contractions of anesthetized dog.
Topics: Anesthesia; Animals; Benzilates; Blood Pressure; Dogs; Female; Flavoxate; Guinea Pigs; Heart Rate; I | 1992 |
Possible mechanisms of action of the antispasmodic agent tiropramide in the isolated detrusor from rats.
Topics: Animals; Calcium; Carbachol; Colforsin; Cyclic AMP; Cytosol; Fura-2; In Vitro Techniques; Male; Musc | 1992 |
Selective inhibition of calcium entry induced by benzylisoquinolines in rat smooth muscle.
Topics: Alkaloids; Animals; Calcium; Calcium Channel Blockers; Estradiol; Female; In Vitro Techniques; Isoqu | 1992 |
Influence of papaverine on rat bladder contractions in vivo.
Topics: Animals; Blood Pressure; Female; Isoproterenol; Models, Biological; Muscle Contraction; Papaverine; | 1992 |
Action of Escherichia coli heat-stable enterotoxin II on isolated sections of mouse ileum.
Topics: Animals; Atropine; Bacterial Toxins; Culture Media; Enterotoxins; Escherichia coli; Escherichia coli | 1992 |
Pharmacological evaluation of GS-389, a novel tetrahydroisoquinoline analog related to higenamine, on vascular smooth muscle.
Topics: Alkaloids; Animals; Aorta, Thoracic; Bicarbonates; Cardiotonic Agents; Drug Interactions; Egtazic Ac | 1992 |
Effects of papaverine on tension and 45Ca-uptake in isolated urinary bladder.
Topics: Animals; Calcium Radioisotopes; Cyclic AMP; Isoproterenol; Muscle Contraction; Muscle, Smooth; Papav | 1991 |
Celiprolol has no direct or indirect relaxing effects in isolated arteries and veins.
Topics: Adrenergic beta-Antagonists; Animals; Arteries; Celiprolol; Dinoprost; In Vitro Techniques; Isometri | 1990 |
Relaxation response of isolated canine veins to agents that act on the adenylate cyclase-cyclic AMP system: further investigation.
Topics: 1-Methyl-3-isobutylxanthine; Adenylyl Cyclases; Adrenergic alpha-Agonists; Animals; Colforsin; Cycli | 1990 |
Blood flow in expanded tissue treated with an anticontractile agent.
Topics: Animals; Guinea Pigs; Lasers; Muscle Contraction; Muscle, Smooth; Papaverine; Premedication; Regiona | 1991 |
Inhibition of calcium entry induced by cularines and isocrasifoline in uterine smooth muscle.
Topics: Alkaloids; Animals; Calcium; Coumarins; Female; In Vitro Techniques; Isoquinolines; Muscle Contracti | 1991 |
Inhibition of airway smooth muscle tone by a phorbol ester in the guinea pig trachea: role of epithelium and receptor reserve of the contractile agent.
Topics: Acetylcholine; Animals; Drug Interactions; Epithelium; Guinea Pigs; Male; Muscle Contraction; Muscle | 1991 |
Myogenic responsiveness in rat hindquarter vessels during constant-flow and constant-pressure perfusion in vitro; effects of various potassium concentrations and of endothelial nitrous oxide blockade.
Topics: Animals; Blood Vessels; Edema; Endothelium, Vascular; Epoprostenol; Hindlimb; In Vitro Techniques; M | 1991 |
Cerebral-artery spasm in vitro.
Topics: Arteriosclerosis; Cerebral Arteries; Dinoprost; Humans; In Vitro Techniques; Muscle Contraction; Nif | 1990 |
Two indices of functional damage of the artery wall parallel the time course of irreversible narrowing in experimental vasospasm in the rabbit.
Topics: Animals; Basilar Artery; Endothelium, Vascular; Ischemic Attack, Transient; Kinetics; Muscle Contrac | 1991 |
Relaxation mechanisms of antispasmodics papaverine and thiphenamil on the human corpus cavernosum.
Topics: Calcium; Diphenylacetic Acids; Dose-Response Relationship, Drug; Humans; In Vitro Techniques; Male; | 1990 |
The level of spontaneous myogenic tone in isolated human posterior ciliary arteries decreases with age.
Topics: Acetylcholine; Adult; Aged; Aging; Arteries; Ciliary Body; Dose-Response Relationship, Drug; Endothe | 1990 |
Effects of postganglionic nerve stimulation in oesophageal achalasia: an in vitro study.
Topics: Adolescent; Adult; Aged; Atropine; Electric Stimulation; Esophageal Achalasia; Esophagogastric Junct | 1990 |
K(+)-channel openers for relaxation of isolated penile erectile tissue from rabbit.
Topics: Animals; Benzopyrans; Cromakalim; Electric Stimulation; Guanidines; In Vitro Techniques; Male; Muscl | 1990 |
Effects of papaverine on human isolated bladder muscle.
Topics: Calcium Channel Blockers; Carbachol; Female; Humans; In Vitro Techniques; Male; Middle Aged; Muscle | 1990 |
[Effects of drugs on the upper urinary tract of the human].
Topics: Calcium; Calcium Channel Blockers; Histamine; Humans; Ion Channels; Kidney; Muscle Contraction; Musc | 1986 |
Interaction between Bay-K-8644 and various relaxant agents on K+-depolarized contracture of guinea pig taenia coli.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1988 |
Characterization of cyclic nucleotide and inositol 1,4,5-trisphosphate-sensitive calcium-exchange activity of smooth muscle cells cultured from the human corpora cavernosa.
Topics: Adult; Calcimycin; Calcium; Cells, Cultured; Desmin; Fluorescent Antibody Technique; Humans; Immunoh | 1988 |
Voltage and time dependency of calcium mediated phasic and tonic responses in rat vas deferens smooth muscle--the effect of some calcium agonist and antagonist agents.
Topics: 3-Pyridinecarboxylic acid, 1,4-dihydro-2,6-dimethyl-5-nitro-4-(2-(trifluoromethyl)phenyl)-, Methyl e | 1988 |
The endothelium modulates adrenergic neurotransmission to canine pulmonary arteries and veins.
Topics: Acetylcholine; Animals; Aorta, Thoracic; Biological Factors; Bretylium Compounds; Dogs; Electric Sti | 1989 |
Electric field stimulation alters the outputs of prostaglandins from isolated rat urinary bladder preparations. Influences of papaverine and tetradotoxin.
Topics: Alprostadil; Animals; Dinoprost; Dinoprostone; Electric Stimulation; Female; In Vitro Techniques; Mu | 1989 |
Alpha-adrenoceptor function in isolated penile circumflex veins from potent and impotent men.
Topics: Adult; Aged; Erectile Dysfunction; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contractio | 1989 |
The role of endothelin in the pathogenesis of vasospasm following subarachnoid haemorrhage.
Topics: Angiography; Animals; Basilar Artery; Dogs; Endothelins; Female; Injections; Ischemic Attack, Transi | 1989 |
[The effect of partusisten, dilatol, papaverine and magnesium sulfate on uterine smooth muscle in vitro].
Topics: Animals; Female; Fenoterol; In Vitro Techniques; Magnesium Sulfate; Muscle Contraction; Muscle, Smoo | 1989 |
Modification by indomethacin of airway contractile responses in normal and sensitized guinea-pigs.
Topics: Animals; Guinea Pigs; In Vitro Techniques; Indomethacin; Lung; Male; Muscle Contraction; Muscle, Smo | 1989 |
Effects of Ca-antagonists and antispasmodic drugs on contraction by ACh in molluscan smooth muscle.
Topics: Acetylcholine; Animals; Bivalvia; Calcium Channel Blockers; Diltiazem; Dimethylphenylpiperazinium Io | 1985 |
Cholinoreceptors of the dentis retractor muscle of the sea urchin Strongylocentrotus intermedius.
Topics: Animals; Cyclic AMP; Epinephrine; Esophagus; Muscle Contraction; Muscles; Papaverine; Parasympatholy | 1985 |
Further evidence of the role of cyclic AMP as a mediator of the depressant effects of beta-adrenoceptor agonists and phosphodiesterase inhibitors on slow-contracting mammalian skeletal muscles.
Topics: Adrenergic beta-Agonists; Animals; Cats; Cyclic AMP; Female; Isoproterenol; Male; Muscle Contraction | 1986 |
Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence.
Topics: Acetylcholine; Diabetes Complications; Diabetes Mellitus; Electric Stimulation; Endothelium, Vascula | 1989 |
[Effects of d-isocorydine on the mouse vas deferens].
Topics: Animals; Aporphines; In Vitro Techniques; Male; Mice; Muscle Contraction; Muscle, Smooth; Papaverine | 1986 |
Relationship of urotensin I induced vasodilatory action in rat thoracic aorta to Ca2+ regulation.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; Bucladesine; Calcimycin; Calcium; Colforsin; Endothe | 1987 |
Relaxation of isolated corpus cavernosum induced by smooth-muscle relaxant drugs. A comparative study.
Topics: Adult; Aged; Humans; In Vitro Techniques; Male; Middle Aged; Muscle Contraction; Muscle Relaxation; | 1988 |
Reactivity of the saphenous vein in diabetics.
Topics: Diabetes Mellitus; Humans; In Vitro Techniques; Muscle Contraction; Muscle, Smooth, Vascular; Norepi | 1988 |
[Comparison of effects of four vasodilators on contractions induced by norepinephrine, KCl, and CaCl2 in isolated rabbit aortic strips].
Topics: Animals; Aorta; Calcium Chloride; Female; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smo | 1988 |
[Effect of an increase in the blood flow through the vessels of skeletal muscle on its functional indices and oxygen demand].
Topics: Acetylcholine; Animals; Cats; Hyperemia; Lactates; Muscle Contraction; Muscles; Oxygen; Oxygen Consu | 1988 |
Effects of Abana, an Ayurvedic preparation, on rabbit atrium and intestine.
Topics: Acetylcholine; Albuterol; Animals; Heart Atria; Ileum; India; Intestines; Isoproterenol; Muscle Cont | 1988 |
Actions of some vasodilators on isolated human hand veins.
Topics: Adolescent; Adult; Aged; Dinoprost; Female; Hand; Humans; Lidocaine; Male; Middle Aged; Muscle Contr | 1987 |
Functional role of aerobic glycolysis in rat portal vein.
Topics: 3-Hydroxybutyric Acid; Animals; Cyanides; Female; Glucose; Glycogen; Glycolysis; Hydroxybutyrates; I | 1987 |
Changes of diameter and length in cylindrical segments of canine femoral arteries during activation at different pressures.
Topics: Animals; Arteries; Dogs; Female; Femoral Artery; Male; Muscle Contraction; Muscle, Smooth, Vascular; | 1987 |
Denervation increases myogenic tone in a resistance artery in the growing rabbit ear.
Topics: Animals; Arteries; Ear; Male; Muscle Contraction; Norepinephrine; Papaverine; Rabbits; Sympathectomy | 1986 |
Quantification of the actions of agonists that simultaneously act on a particular type of receptor and have separate functional interactant properties.
Topics: Animals; Carbachol; In Vitro Techniques; Jejunum; Male; Muscle Contraction; Muscle, Smooth; Papaveri | 1986 |
[Effect of oxybutynin hydrochloride on isolated smooth muscles (ileum, urinary bladder and urethra)].
Topics: Acetylcholine; Animals; Drug Interactions; Female; Guinea Pigs; Ileum; In Vitro Techniques; Male; Ma | 1986 |
Identification and molecular characterization of the isoquinoline rat intestinal binding site using 6,7-dimethoxy-4-(4'-amino-3'-[125I]iodobenzyl) isoquinoline.
Topics: Animals; Barium; Barium Compounds; Binding Sites; Binding, Competitive; Calcium Channel Blockers; Ce | 1986 |
Effect of a smooth muscle relaxant from the stonefish, Synanceia trachynis, on KCl-induced responses in the guinea-pig vas deferens.
Topics: Animals; Calcium; Fish Venoms; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscle, S | 1986 |
Mechanisms of venous occlusion during canine penile erection: an anatomic demonstration.
Topics: Animals; Dogs; Humans; Male; Microscopy, Electron, Scanning; Muscle Contraction; Muscle, Smooth, Vas | 1987 |
Selective hemoglobin inhibition of endothelium-dependent vasodilation of rabbit basilar artery.
Topics: Acetylcholine; Adenosine Triphosphate; Animals; Basilar Artery; Endothelium; Hemoglobins; Male; Musc | 1986 |
The effects of piperidine and its related substances on blood vessels.
Topics: Animals; Blood Pressure; Carotid Arteries; Coronary Vessels; Dogs; Electrocardiography; Female; Femo | 1985 |
Quantification of the characteristics of antagonists exhibiting both competitive antagonism and functional interaction.
Topics: Animals; Atropine; Binding, Competitive; Carbachol; Drug Antagonism; Drug Interactions; Guinea Pigs; | 1985 |
Antagonistic activity of aligeron and papaverine against different smooth muscle stimuli.
Topics: Animals; Cinnarizine; Epinephrine; Guinea Pigs; In Vitro Techniques; Male; Muscle Contraction; Muscl | 1985 |
Adrenergic influences on uterine smooth muscle.
Topics: Animals; Butyrates; Calcium; Chlorides; Cyclic AMP; Female; In Vitro Techniques; Isoproterenol; Lant | 1973 |
Effects of oxyfedrine on isolated portal vein and other smooth muscles.
Topics: Adrenergic beta-Agonists; Amino Alcohols; Animals; Calcium Chloride; Carbachol; Dogs; Duodenum; Fema | 1973 |
Dopamine-induced relaxation of isolated arterial strips.
Topics: Animals; Dogs; Dopamine; Femoral Artery; Guinea Pigs; Haplorhini; In Vitro Techniques; Mesenteric Ar | 1973 |
Mode of antagonism between beta-adrenergic drugs and prostaglandin F2-alpha.
Topics: Adrenergic beta-Antagonists; Animals; Bronchial Spasm; Dose-Response Relationship, Drug; Guinea Pigs | 1974 |
Antispasmodic action of quaternary compounds administered orally.
Topics: Animals; Atropine; Male; Muscle Contraction; Papaverine; Parasympatholytics; Piperidines; Pressure; | 1974 |
Vorticella--a model for chemopharmacodynamic action on smooth muscle.
Topics: Adenosine; Amides; Anesthetics, Local; Animals; Ciliophora; Culture Media; Cyanides; Ferricyanides; | 1972 |
Differences in papaverine inhibition of prostaglandin-induced contraction of aortic strips from normal and spontaneously hypertensive rats (SHR).
Topics: Animals; Aorta, Thoracic; Blood Pressure; Hypertension; In Vitro Techniques; Muscle Contraction; Mus | 1974 |
[Basic directions in the study of the biochemistry of the myocardium].
Topics: Adaptation, Physiological; Animals; Camphor; Cardiac Glycosides; Cardiomegaly; Cardiovascular Diseas | 1967 |
Inhibition of prostaglandin effects by ouabain in the canine vascular tissue.
Topics: Adenosine Triphosphatases; Animals; Atropine; Dogs; Mesenteric Arteries; Mesenteric Veins; Muscle Co | 1969 |
[Behavior of a spontaneously active vascular smooth muscle in vitro under the influence of various cations and drugs].
Topics: Acetylcholine; Adenine Nucleotides; Animals; Calcium; Epinephrine; In Vitro Techniques; Isoprotereno | 1969 |
The effect of adenosinetriphosphoric acid upon the action of spasmolytic drugs.
Topics: Action Potentials; Adenosine Triphosphate; Animals; Cell Membrane; Drug Synergism; Female; In Vitro | 1970 |
Catechol-o-methyl transferase inhibition and potentiation of epinephrine responses by desmethylpapavernine.
Topics: Angiotensin II; Animals; Aorta; Cats; Enzymes; Epinephrine; Ileum; In Vitro Techniques; Keto Acids; | 1965 |
Angiotensin in the analysis of the intrinsic nerve supply of isolated intestines.
Topics: Angiotensin II; Animals; Atropine; Cocaine; Epinephrine; Gerbillinae; Hexamethonium Compounds; Ileum | 1968 |
Inhibition by lidoflazine of the contractile response of the rat isolated colon to angiotensin.
Topics: Acetylcholine; Angiotensin II; Animals; Barium; Colon; Drug Synergism; In Vitro Techniques; Muscle C | 1969 |
Contraction of granulation tissue in vitro: similarity to smooth muscle.
Topics: Angiotensin II; Animals; Bradykinin; Epinephrine; Fibroblasts; Granulation Tissue; Histamine; In Vit | 1971 |
Studies on the neuropharmacology of papaverine. I. The curare-like action isolated nerve-muscle preparation.
Topics: Acetylcholine; Animals; Caffeine; Depression, Chemical; Diaphragm; Drug Interactions; Drug Synergism | 1971 |
Studies on the neuropharmacology of papaverine. II. The effect on neuromuscular transmission in the whole animal.
Topics: Animals; Blood Pressure; Cats; Decamethonium Compounds; Depression, Chemical; Drug Interactions; Dru | 1971 |
Actions of dibutyryl cyclic adenosine monophosphate, papaverine and isoprenaline on the intestinal smooth muscle.
Topics: Animals; Caffeine; Colon; Cyclic AMP; Glycerol; Guinea Pigs; In Vitro Techniques; Intestines; Isopro | 1971 |
Cyclic AMP and smooth muscle function.
Topics: Adenylyl Cyclases; Animals; Aorta, Abdominal; Aorta, Thoracic; Arteries; Cyclic AMP; Depression, Che | 1971 |
Accumulation of adenosine 3',5'-monophosphate and relaxation in the rat uterus in vitro.
Topics: Animals; Butyrates; Cyclic AMP; Depression, Chemical; Diazoxide; Drug Interactions; Female; Fluoride | 1971 |
The prevention of isoproterenol desensitization and isoproterenol reversal.
Topics: Aminophylline; Angiotensin II; Animals; Aorta; Bromine; Desensitization, Immunologic; Drug Interacti | 1972 |
Cyclic nucleotide phosphodiesterase inhibition and vascular smooth muscle relaxation.
Topics: Animals; Aorta, Thoracic; Barium; Benzyl Compounds; Cyclic AMP; Drug Antagonism; Drug Interactions; | 1972 |
Effect of cholecystokinin on the level of cyclic AMP and on mechanical activity in the isolated sphincter of Oddi.
Topics: Adenylyl Cyclases; Ampulla of Vater; Animals; Cats; Cholecystokinin; Cyclic AMP; Glucagon; Imidazole | 1972 |
Papaverine antagonism of prostaglandin E 2 -induced contraction of rabbit aortic strips.
Topics: Animals; Aorta, Thoracic; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Drug Interactions; | 1973 |
A possible etiology of contractility impairment of vascular smooth muscle from spontaneously hypertensive rats.
Topics: Angiotensin II; Animals; Aorta, Thoracic; Barium; Blood Pressure; Calcium; Cobalt; Hypertension; In | 1973 |
On the possible role of cyclic AMP in the neuromuscular transmission and in the treatment of myasthenia gravis.
Topics: Cyclic AMP; Humans; Muscle Contraction; Myasthenia Gravis; Papaverine; Stimulation, Chemical; Synapt | 1972 |
[Role of cyclic AMP in the mechanical activity of smooth muscle].
Topics: Adenylyl Cyclase Inhibitors; Adenylyl Cyclases; Calcium; Catecholamines; Cell Membrane; Cyclic AMP; | 1973 |
Intracellular cyclic AMP level and intestinal smooth muscle relaxation.
Topics: Animals; Benzyl Compounds; Butanols; Cecum; Cyclic AMP; Dose-Response Relationship, Drug; Guinea Pig | 1974 |
Beta-adrenergic effects on rat myometrium: role of cyclic AMP.
Topics: Animals; Calcium; Cyclic AMP; Depression, Chemical; Drug Interactions; Female; Isoproterenol; Lantha | 1974 |
Proceedings: Effects of papaverine derivatives on cyclic 3', 5'-AMP phosphodiesterase and relaxation of rabbit ileum.
Topics: Animals; Bucladesine; Cyclic AMP; Ileum; In Vitro Techniques; Muscle Contraction; Papaverine; Phosph | 1974 |
Anti-allergic actions of disodium cromoglycate and other drugs known to inhibit cyclic 3',5'-nucleotide phosphodiesterase.
Topics: Adenosine Triphosphate; Aminophylline; Anaphylaxis; Animals; Bordetella pertussis; Bucladesine; Crom | 1974 |
Comparison of actions of papaverine, aspaminol and isoprenaline on isolated rat uterus.
Topics: Aminophylline; Animals; Benzyl Compounds; Butanols; Cyclic AMP; Drug Synergism; Female; Imidazoles; | 1974 |
Age-related changes in vascular responsiveness to cyclic nucleotides and contractile agonists.
Topics: Aging; Animals; Aorta, Thoracic; Benzyl Compounds; Bucladesine; Cyclic AMP; Cyclic GMP; Dose-Respons | 1974 |
Effects of papaverine on the rabbit ileum under the influence of altered temperature and extracellular Ca2+.
Topics: Animals; Calcium; Cyclic AMP; Dose-Response Relationship, Drug; Gastrointestinal Motility; Ileum; In | 1974 |
Rat diaphragm cyclic nucleotide-phosphodiesterase: influence of drugs affecting skeletal muscle contractility.
Topics: Animals; Bucladesine; Cyclic AMP; Cyclic GMP; Dialysis; Diaphragm; Hydrochlorothiazide; Hydrogen-Ion | 1974 |
[Actions of papaverine, aspaminol and bile salts and intracellular cyclic AMP level].
Topics: Aminophylline; Animals; Benzyl Compounds; Bile Acids and Salts; Butanols; Calcium Chloride; Castrati | 1974 |
Role of cyclic 3',5'-AMP on contraction and relaxation of perfused rat caudal artery.
Topics: Animals; Arteries; Blood Pressure; Cyclic AMP; Dose-Response Relationship, Drug; Electric Stimulatio | 1974 |
The adrenergic blocking activity of N-tert.-butylmethoxamine (butoxamine).
Topics: Animals; Blood Circulation; Blood Pressure; Dogs; Epinephrine; Ethanolamines; Female; Gastrointestin | 1966 |
[Contractile response of the tracheal musculature to various pharmacologic agents].
Topics: Acetylcholine; Animals; Atropine; Barium; Cats; Diphenhydramine; Ganglionic Blockers; Guinea Pigs; H | 1966 |
Pharmacological reactivity of an isolated tracheal preparation of the guinea-pig.
Topics: Acetylcholine; Animals; Atropine; Barium; Chlorisondamine; Chlorpheniramine; Diphenhydramine; Ethano | 1966 |
[Anti-bradykinin action of diphenhydramine on the excised ileum of guinea pigs].
Topics: Animals; Aspirin; Barium; Blood Pressure; Bradykinin; Chlorpheniramine; Diphenhydramine; Ethanol; Gu | 1966 |
The effect of 6-azauridine on the contractile responses of the isolated ileum of the guinea-pig to drugs and to coaxial stimulation.
Topics: Acetylcholine; Animals; Antimetabolites; Barium; Electric Stimulation; Electrophysiology; Guinea Pig | 1966 |
The effect of isoprenaline on the contraction of smooth muscle produced by histamine, acetylcholine or other agents.
Topics: Acetylcholine; Animals; Atropine; Bradykinin; Bronchial Spasm; Chlorpheniramine; Creatine; Drug Anta | 1966 |
Pharmacological properties of tetrahydropapaveroline.
Topics: Acetylcholine; Animals; Anura; Barium; Blood Flow Velocity; Blood Pressure; Cats; Dogs; Duodenum; El | 1967 |
An effect of histamine on the nictitating membrane of the cat: potentiation of the actions of adrenaline, noradrenaline and acetylcholine.
Topics: Acetylcholine; Adenosine Triphosphate; Angiotensin II; Animals; Blood Pressure; Bradykinin; Catechol | 1967 |
The action of isoprenaline in the depolarized rat uterus.
Topics: Animals; Barium; Calcium Chloride; Chelating Agents; Culture Techniques; Edetic Acid; Female; Isopro | 1967 |
[Effects of various drugs on the contraction of the excised vas deferens by hypogastric nerve and transmural stimulations in guinea pigs].
Topics: Abdominal Muscles; Acetylcholine; Animals; Atropine; Bretylium Compounds; Dibenzylchlorethamine; Ele | 1967 |
[Research on the spasmolytic capacity of Tweens].
Topics: Acetylcholine; Amines; Animals; Atropine; Barium; Duodenum; Guinea Pigs; Histamine Antagonists; Hist | 1967 |
Quinterenol, a new beta adrenergic stimulant.
Topics: Acetylcholine; Anaphylaxis; Animals; Blood Pressure; Cardiac Output; Cats; Chlorpromazine; Dogs; Fem | 1968 |
Gastric motor-stimulating activity of gastrin tetrapeptide in dogs.
Topics: Animals; Atropine; Blood Pressure; Carbachol; Chlorpromazine; Colon; Dogs; Duodenum; Gastrins; Gastr | 1969 |
An evaluation of the adrenergic receptor types in isolated segments of the small intestine of the rabbit.
Topics: Acetylcholine; Animals; Atropine; Drug Antagonism; Duodenum; Epinephrine; Histamine; Histamine H1 An | 1968 |
[Pharmacological study of phenethyl-8-oxa-1-diaza-3,8-spiro(4,5)decanone-2 hydrochloride or fenspiride (JP 428)].
Topics: Anaphylaxis; Anesthesia; Animals; Anti-Inflammatory Agents; Atropine; Autonomic Nervous System; Bron | 1969 |
[Spasmolytic effect of aryl-substituted alpha-pyrones and aqueous extracts of Piper methysticum Forst].
Topics: Animals; Anticonvulsants; Benzocaine; Chromatography, Thin Layer; Cocaine; Guinea Pigs; Histamine; H | 1969 |
[Pharmacodynamic properties of 1-(2'-piperidine-ethyl)-4,4-bis-(para-methoxy-phenyl)-2,5-imidazolidinedione-chlorhydrate (I. 255). Studies of the effect on musculature of intestine gallbladder, uterus, bladder and trachea in vitro].
Topics: Acetylcholine; Animals; Atropine; Barium; Cats; Chlorides; Colon; Depression, Chemical; Duodenum; Fe | 1970 |
Non-competitive spasmolytics as antagonists of Ca++-induced smooth muscle contraction.
Topics: Acetylcholine; Animals; Calcium; Cecum; Chlorides; Cocaine; Cyanides; Cyclohexanes; Dinitrophenols; | 1971 |
The inducement of tone and its inhibition in isolated tracheal muscle.
Topics: Animals; Atropine; Bronchodilator Agents; Epinephrine; Ethanol; Guinea Pigs; In Vitro Techniques; Is | 1971 |
On the mechanism of papaverine action on the control of vascular smooth muscle contractile activity by extracellular calcium.
Topics: Animals; Aorta; Calcium; Cyclic AMP; In Vitro Techniques; Male; Muscle Contraction; Muscle, Smooth; | 1971 |
Investigation on pharmacological properties of hexadiphane, oxazepam hemisuccinate and of their combination.
Topics: Animals; Azepines; Benzene Derivatives; Diphenylacetic Acids; Drug Synergism; Female; Gallbladder; G | 1972 |
Cardiac toxicity of -lytic drugs.
Topics: 1-Propanol; Acetanilides; Adrenergic beta-Antagonists; Alprenolol; Amino Alcohols; Animals; Cresols; | 1972 |
The influence of drugs upon 42 K + fluxes in guinea-pig ileum in vitro.
Topics: Acetylcholine; Animals; Atropine; Barium; Carbachol; Epinephrine; Guinea Pigs; Histamine; Histamine | 1972 |
Inhibitory action of some antihistaminics on the anaphylactic contraction in guinea pig's taenia coli.
Topics: Anaphylaxis; Animals; Antigen-Antibody Reactions; Antigens; Atropine; Barium; Binding, Competitive; | 1972 |
[Effect of several saluretic agents on smooth muscle. A contribution to the varied effects of saluretic agents on glomerular filtration (author's transl)].
Topics: Animals; Chlorthalidone; Diuretics; Female; Furans; Furosemide; Glomerular Filtration Rate; Hemodyna | 1974 |
Role of potassium ions in the vascular response to a brief tetanus.
Topics: Animals; Capillaries; Dilatation; Dogs; Hyperemia; Mathematics; Models, Biological; Muscle Contracti | 1974 |
The action of vasodilating drugs on isolated basilar, coronary and mesenteric arteries of the dog.
Topics: Acetylcholine; Adenosine; Aminophylline; Animals; Atropine; Basilar Artery; Coronary Vessels; Dogs; | 1974 |
Influence of papaverine and nitrite on the responses to norepinephrine of inner and outer smooth muscle of sheep carotid arteries.
Topics: Animals; Calcium; Carotid Arteries; Depression, Chemical; Desipramine; Muscle Contraction; Muscle, S | 1974 |
Action of gentamicin, aminosidin, and ampicillin on uterine tone and motility.
Topics: Ampicillin; Animals; Anti-Bacterial Agents; Depression, Chemical; Dogs; Female; Gentamicins; Guinea | 1972 |
3(2H)-isoquinolones. 1. 3-Oxygenated analogs of papaverine as peripheral vasodilators.
Topics: Animals; Blood Pressure; Cardiac Output; Coronary Circulation; Dogs; Dose-Response Relationship, Dru | 1972 |
[Analysis of the distribution of Ca 45 in isolated rat aorta using spasmolytic substances].
Topics: Animals; Aorta; Biological Transport; Calcium; Calcium Isotopes; Chlorides; Cinnamates; In Vitro Tec | 1972 |
Effect on the rat uterus of the venom from the scorpion Leiurus quinquestriatus.
Topics: Animals; Atropine; Chlorpheniramine; Cocaine; Diphenhydramine; Estrus; Female; Hexamethonium Compoun | 1972 |
[Cardiovascular effects of guaiacol glycerol ether mononicotinate].
Topics: Amobarbital; Anesthesia, General; Animals; Blood Pressure; Cardiovascular System; Dogs; Electrocardi | 1972 |
Quantitative aspects of drug-receptor interactions. II. The role of Ca2+men in desensitization and spasmolytic activity.
Topics: Animals; Binding Sites; Calcium; Cell Membrane; Dioxoles; Drug Tolerance; Guinea Pigs; In Vitro Tech | 1973 |
Myogenic peristalsis in isolated preparations of chicken oesophagus.
Topics: Acetylcholine; Animals; Chickens; Cocaine; Esophagus; Female; Gastrointestinal Motility; In Vitro Te | 1973 |
Inhibitory action of spermine on the contractions of rat uterus.
Topics: Animals; Calcium; Electrophysiology; Female; Muscle Contraction; Muscle, Smooth; Papaverine; Pregnan | 1973 |
A study of compounds which inhibit vascular smooth muscle contraction.
Topics: Animals; Aorta, Thoracic; Barium; Blood Vessels; Dose-Response Relationship, Drug; Female; Guanidine | 1973 |
Action mechanisms of the contracting drugs, K, acetylcholine and Ba, and of the relaxants, isoproterenol and papaverine in the rat's isolated ileum, especially in relation to Ca.
Topics: Acetylcholine; Animals; Barium; Calcium; Ileum; In Vitro Techniques; Isoproterenol; Muscle Contracti | 1973 |
Proceedings: Sensitivity of inner and outer parts of the medulla of the sheep carotid artery to vasodilator drugs.
Topics: Animals; Carotid Arteries; In Vitro Techniques; Isoproterenol; Muscle Contraction; Muscle, Smooth; N | 1973 |
Properties of exercise and reactive hyperemias in canine hindlimb muscles under constant pressure perfusion.
Topics: Animals; Arteries; Blood Volume; Cats; Dogs; Electric Stimulation; Female; Hindlimb; Hyperemia; Male | 1973 |
Studies concerning the source of calcium for contraction of rat myometrium.
Topics: Acetylcholine; Action Potentials; Animals; Calcium; Calcium Radioisotopes; Carbon Radioisotopes; Chl | 1973 |
Some effects of histamine in the depolarized rat uterus.
Topics: Acetates; Acetylcholine; Animals; Barium; Buffers; Calcium; Calcium Radioisotopes; Cell Membrane Per | 1973 |
[Inhibitory action of protamine and lanthanum on the smooth muscle].
Topics: Acetylcholine; Animals; Calcium; Cecum; Depression, Chemical; Dose-Response Relationship, Drug; Guin | 1973 |
[Mode of action of spasmogens (K, acetylcholine, Ba) and antispasmodics (isoproterenol, papaverine, chlorpromazine) on excised vas deferens of the rabbit, with special reference to their relationship with Ca].
Topics: Acetylcholine; Animals; Barium; Calcium; Chlorpromazine; Dinitrophenols; In Vitro Techniques; Isopro | 1973 |
[Experimental studies of anthelmintics. 21. Pharmacological studies of 1-(2-(dodecyloxy)ethyl) pyrrolidine hydrochloride (DEP) on ascaris lumbricoidessuum].
Topics: Acetylcholine; Alkanes; Animals; Anthelmintics; Ascaris; Atropine; Calcium; Culture Media; Ethers; H | 1973 |
[Proceedings: Contractions and relaxations of the vascular smooth muscle. 3. Papaverine relaxation responses in Ca and Ba solutions].
Topics: Animals; Barium; Blood Vessels; Calcium; Dogs; In Vitro Techniques; Isoproterenol; Muscle Contractio | 1973 |
[Proceedings: Mechanism of inhibitory action of papaverine on K-induced contraction of the intestinal smooth muscle].
Topics: Animals; In Vitro Techniques; Intestines; Muscle Contraction; Muscle, Smooth; Papaverine; Potassium; | 1973 |
[Mechanism of spasmolytic action of 4-methylumbelliferone].
Topics: Ampulla of Vater; Animals; Aorta, Thoracic; Atropine; Catechol O-Methyltransferase Inhibitors; Couma | 1973 |
Effects of drugs on 47Ca2+ movements in depolarized longitudinal smooth muscle.
Topics: Acetylcholine; Animals; Calcium; Calcium Radioisotopes; Carbachol; Epinephrine; Guinea Pigs; Histami | 1974 |
Emotion-induced headache.
Topics: Ergotamine; Fluphenazine; Headache; Humans; Methysergide; Migraine Disorders; Muscle Contraction; Pa | 1974 |
Effects of vasodilators on the isolated taenia coli of the guinea-pig.
Topics: Aminophylline; Animals; Calcium; Cell Membrane; Electrophysiology; Epinephrine; Guinea Pigs; In Vitr | 1967 |
Smooth muscle relaxants: dissociation between resting membrane potential and resting tension in rat myometrium.
Topics: Animals; Catecholamines; Epinephrine; Female; In Vitro Techniques; Isoproterenol; Membrane Potential | 1969 |
A comparison of the effects of various smooth muscle relaxants on the electrical and mechanical activity of rat uterus.
Topics: Action Potentials; Animals; Calcium; Cell Membrane; Electricity; Epinephrine; Female; In Vitro Techn | 1969 |
[Action of nitroglycerin and intravenous injections of papaverine on the contractile function of the heart in patients with coronary circulatory disorders].
Topics: Adult; Aged; Coronary Disease; Female; Heart; Humans; Hypertension; Injections, Intravenous; Male; M | 1969 |
Effects of nitroglycerin (trinitrin) on vascular smooth muscle.
Topics: Acetylcholine; Animals; Aorta; Blood Flow Velocity; Blood Pressure; Blood Vessels; Constriction; Dog | 1970 |
[The connection between the influence on urease activity and the pharmacological effect of some drugs with cardiac and coronary activity].
Topics: Amino Alcohols; Animals; Binding Sites; Cardanolides; Cardiac Glycosides; Cats; Coronary Circulation | 1972 |
Electrophysiological investigations on the mechanism of action of some spasmolytic agents.
Topics: Acetylcholine; Action Potentials; Alkaloids; Animals; Benzyl Compounds; Calcium; Colon; Drug Interac | 1972 |
[Pharmacological effects on the contraction frequency of isolated rat portal vein].
Topics: Aconitum; Animals; Atropine; Caffeine; Carbachol; Epinephrine; Histamine; In Vitro Techniques; Isopr | 1972 |
The Anrep effect reconsidered.
Topics: Adenosine Triphosphate; Aminophylline; Animals; Blood Flow Velocity; Blood Pressure; Catheterization | 1972 |
[Action of papaverine on calcium distribution in the rat aorta stimulated by potassium].
Topics: Animals; Aorta; Biological Transport; Calcium; Calcium Isotopes; Depression, Chemical; Diffusion; Dr | 1972 |
Positive inotropic effects of papaverine and aminophylline on isolated human atrial preparations.
Topics: Aminophylline; Drug Interactions; Electric Stimulation; Heart Atria; Humans; In Vitro Techniques; Is | 1972 |
Unidirectional rate sensitivity component in local control of vascular tone.
Topics: Animals; Blood Flow Velocity; Blood Pressure; Blood Vessels; Dogs; Muscle Contraction; Muscle Tonus; | 1971 |
Effects of papaverine, eupaverin and isoxsuprine on the electrical and mechanical activity of guinea-pig 'taenia coli'.
Topics: Acetylcholine; Animals; Calcium; Colon; Drug Antagonism; Drug Interactions; Electric Stimulation; Gu | 1971 |
Papaverine blockade of the calcium action in depolarized taenia coli of the guinea-pig.
Topics: Acetylcholine; Animals; Calcium; Colon; Guinea Pigs; Membrane Potentials; Muscle Contraction; Muscle | 1971 |
Pharmacological responses of the smooth muscle of the pig's excised coronary artery, especially in relation to Ca.
Topics: Acetylcholine; Animals; Arteries; Barium; Calcium; Coronary Vessels; In Vitro Techniques; Isoprotere | 1971 |
Activation of vascular smooth muscle of rat aorta by noradrenaline and depolarization: two different mechanisms.
Topics: Animals; Aorta; Constriction; Female; Hydrogen-Ion Concentration; Male; Muscle Contraction; Muscle, | 1971 |
[Studies on the mechanical properties of strips cut under different angles from the abdominal aorta of rabbits].
Topics: Animals; Aorta; Aorta, Abdominal; Biomechanical Phenomena; In Vitro Techniques; Muscle Contraction; | 1968 |
Spasmolytic action of 4-methylumbelliferone in isolated guinea-pig's gallbladder.
Topics: Acetylcholine; Animals; Atropine; Barium; Coumarins; Diphenhydramine; Gallbladder; Guinea Pigs; In V | 1971 |
Pharmacological investigations of usaramine, an alkaloid isolated from Crotalaria brevifolia.
Topics: Alkaloids; Animals; Blood Pressure; Cardiac Output; Dogs; Female; Guinea Pigs; Heart; Male; Mice; Mu | 1969 |
[Effect of alpha receptor blocking on the activity of preparations stimulating and inhibiting the uterine contractility in the rat].
Topics: Acetylcholine; Animals; Catecholamines; Epinephrine; Female; Muscle Contraction; Norepinephrine; Oxy | 1969 |
[Studies on tetrahydroisoquinolines. V. Actions of 1-(3, 4, 5-trimethoxybenzyl)-6, 7-dihydroxy-1, 2, 3, 4-tetrahydroisoquinoline HCL (AQ-110) on the guinea-pig papillary muscle].
Topics: Animals; Bronchodilator Agents; Chemical Phenomena; Chemistry; Depression, Chemical; Drug Antagonism | 1969 |
Effect of papaverine on potassium and caffeine-induced contractures on frog skeletal muscle.
Topics: Animals; Anura; Caffeine; Muscle Contraction; Muscles; Papaverine; Potassium | 1969 |
5,5-diphenyl-2-(2'-piperidinoethyl)-1,3-dioxolane-4-one a new drug with potent spasmolytic activity.
Topics: Acetylcholine; Animals; Asthma; Atropine; Barium; Blood Pressure; Blood Vessels; Carbachol; Cats; Ch | 1970 |
Antinicotinic properties of papaverine in guinea pig taenia coli.
Topics: Acetylcholine; Animals; Depression, Chemical; Evoked Potentials; Guinea Pigs; In Vitro Techniques; I | 1970 |
Antispasmodic agents. 1. Syntheses and pharmacological activity of aminoalkyl 3-substituted phenylacetates.
Topics: Amines; Animals; Atropine; Chemical Phenomena; Chemistry; Ileum; Muscle Contraction; Papaverine; Par | 1971 |
[On the stimulating effect of procaine on the isolated guinea pig ileum].
Topics: Acetylcholine; Animals; Atropine; Calcium; Drug Antagonism; Electric Stimulation; Epinephrine; Guine | 1967 |
Antispasmodic activity in vitro of some pentoxyverine derivatives.
Topics: Acetylcholine; Animals; Barium; Chlorides; Cyclohexanes; Cyclopentanes; Duodenum; Guinea Pigs; Ileum | 1967 |
[The effects of spasmolytics on the mechanical and electrical activity of isolated rat uterus].
Topics: Acetylcholine; Action Potentials; Animals; Depression, Chemical; Female; In Vitro Techniques; Meperi | 1967 |
[Experimental studies of a new spasmoanalgetic on the rat uterus and 1st clinical experience in obstetrics].
Topics: Acetates; Adult; Animals; Female; Humans; In Vitro Techniques; Injections, Intravenous; Labor, Obste | 1968 |
On the mechanism of action of some myolytic agents on depolarized guinea pig taenia coli.
Topics: Animals; Calcium; Cyanides; Guinea Pigs; Intestines; Muscle Contraction; Muscle, Smooth; Muscles; Pa | 1968 |
[Antispasmodic action of 4'-[N-ethyl-1"-methyl-2"-(4"-methoxyphenyl)ethylamino] butyl-3, 4-dimethoxybenzoate hydrochloride (Mebeverine) on the gastrointestinal tract].
Topics: Animals; Benzoates; Blood Pressure; Cats; Colon; Dogs; Electrocardiography; Female; Gastrointestinal | 1968 |
Ureteral stones. An experimental and clinical study of the mechanism of the passage and arrest of ureteral stones.
Topics: Adult; Aluminum; Animals; Biomechanical Phenomena; Contrast Media; Dilatation; Elastic Tissue; Elast | 1968 |
Comparative bioassay of vasoactive drugs using isolated perfused rabbit arteries.
Topics: Animals; Arteries; Biological Assay; Cardiovascular System; Ergotamine; In Vitro Techniques; Methods | 1969 |
Some pharmacological properties of 4H-3-methylcarboxamide 1,3-benzoxazine-2-one (FI 6654).
Topics: Acetylcholine; Animals; Antidepressive Agents; Arousal; Atropine; Barium; Duodenum; Electroencephalo | 1969 |
[Effect of the uterine contractility depressing agents on the electrical phenomena of the cell membrane after beta-receptors blockade].
Topics: Action Potentials; Animals; Drug Synergism; Epinephrine; Female; Membrane Potentials; Muscle Contrac | 1969 |
The influence of beta-receptors' blockade upon the action of rat's uterus contractility inhibiting agents.
Topics: Alcohols; Animals; Benzilates; Chlordiazepoxide; Drug Synergism; Epinephrine; Female; Humans; In Vit | 1969 |
[Role of calcium in the contractile process and the mechanism of action of spasmolytics].
Topics: Acetylcholine; Animals; Calcium; Colon; Duodenum; Guinea Pigs; Ileum; In Vitro Techniques; Muscle Co | 1965 |
Dimethyl isopropylmethoxamine: a selective beta-receptor blocking agent.
Topics: 1-Propanol; Animals; Blood Flow Velocity; Blood Pressure; Dogs; Epinephrine; Female; Femoral Artery; | 1966 |
Potentiation of adenosine and the adenine nucleotides by dipyridamole.
Topics: Acetylcholine; Adenine Nucleotides; Adenosine Triphosphate; Animals; Arrhythmias, Cardiac; Azaguanin | 1966 |