papaverine has been researched along with Migraine Disorders in 14 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Migraine Disorders: A class of disabling primary headache disorders, characterized by recurrent unilateral pulsatile headaches. The two major subtypes are common migraine (without aura) and classic migraine (with aura or neurological symptoms). (International Classification of Headache Disorders, 2nd ed. Cephalalgia 2004: suppl 1)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 13 (92.86) | 18.7374 |
| 1990's | 1 (7.14) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| BYRNE-QUINN, E | 1 |
| KRISCHEK, J | 1 |
| Raskin, NH | 1 |
| Schwartz, RK | 1 |
| D'Amore, MJ | 1 |
| Borge, MA | 1 |
| Messersmith, RN | 1 |
| Sillanpää, M | 1 |
| Koponen, M | 1 |
| Vijayan, N | 1 |
| Poser, CM | 1 |
| Welch, KM | 1 |
| Spira, PJ | 1 |
| Knowles, L | 1 |
| Lance, JW | 1 |
| Ancalmo, N | 1 |
| Ochsner, JL | 1 |
| Hadjiev, D | 1 |
| Simard, D | 2 |
| Paulson, OB | 2 |
| Pechadre, JC | 1 |
| Aring, CD | 1 |
| von Albert, HH | 1 |
| Marguth, F | 1 |
1 review available for papaverine and Migraine Disorders
| Article | Year |
|---|---|
Impedance methods for investigation of cerebral circulation.
Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Carbon Dioxide; Carotid Artery Diseases; Cerebral | 1972 |
1 trial available for papaverine and Migraine Disorders
| Article | Year |
|---|---|
Papaverine in the prophylaxis of migraine and other vascular headache in children.
Topics: Adolescent; Child; Clinical Trials as Topic; Double-Blind Method; Drug Evaluation; Follow-Up Studies | 1978 |
12 other studies available for papaverine and Migraine Disorders
| Article | Year |
|---|---|
PROLONGED ARTERIOSPASM AFTER OVERDOSE OF ORAL ERGOTAMINE TARTRATE IN MIGRAINE.
Topics: Anticoagulants; Arteries; Ergotamine; Humans; Migraine Disorders; Papaverine; Poisoning; Spasm; Toxi | 1964 |
[Migraine therapy with migraine kranit].
Topics: Acetaminophen; Antipyrine; Caffeine; Drug Combinations; Humans; Migraine Disorders; Muscle Relaxants | 1951 |
Interval therapy of migraine: long-term results.
Topics: Adolescent; Adult; Aged; Amitriptyline; Cyproheptadine; Ergonovine; Ergotamine; Humans; Middle Aged; | 1980 |
Limb-threatening lower extremity ischemia successfully treated with intra-arterial infusion--case reports.
Topics: Adult; Caffeine; Central Nervous System Stimulants; Drug Combinations; Ergotamine; Female; Follow-Up | 1999 |
Brief therapeutic report: papaverine prophylaxis of complicated migraine.
Topics: Catecholamines; Delayed-Action Preparations; Humans; Migraine Disorders; Papaverine | 1977 |
Letter: Papaverine in prophylactic treatment of migraine.
Topics: Humans; Migraine Disorders; Papaverine | 1974 |
Simultaneous measurement of internal and external carotid blood flow in the monkey. An approach to the study of migraine mechanisms.
Topics: Animals; Blood Pressure; Carbon Dioxide; Carotid Arteries; Carotid Artery, External; Carotid Artery, | 1974 |
Peripheral ischemia secondary to ergotamine intoxication.
Topics: Adult; Angiography; Ergotamine; Foot; Foot Diseases; Gangrene; Humans; Ischemia; Leg; Male; Migraine | 1974 |
Cerebral vasomotor paralysis during migraine attack.
Topics: Adult; Blood Pressure; Carbon Dioxide; Cerebrovascular Circulation; Ergotamine; Humans; Hyperventila | 1973 |
Vasomotor paralysis in migraine.
Topics: Adult; Carbon Dioxide; Cerebral Arteries; Cerebrovascular Circulation; Ergolines; Humans; Male; Migr | 1973 |
Emotion-induced headache.
Topics: Ergotamine; Fluphenazine; Headache; Humans; Methysergide; Migraine Disorders; Muscle Contraction; Pa | 1974 |
[Therapy of headaches, including migraine].
Topics: Analgesics; Brain Injuries; Brain Neoplasms; Drug Synergism; Ergoloid Mesylates; Eye Diseases; Heada | 1969 |