papaverine has been researched along with Metastase in 2 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effect of papaverine on transplantable C1300 murine neuroblastoma model was evaluated." | 7.66 | A study of the effect of papaverine in neuroblastoma using the experimental C1300 murine system. ( Murphy, GP; Wajsman, Z; Williams, P, 1978) |
| "The effect of papaverine on transplantable C1300 murine neuroblastoma model was evaluated." | 3.66 | A study of the effect of papaverine in neuroblastoma using the experimental C1300 murine system. ( Murphy, GP; Wajsman, Z; Williams, P, 1978) |
| "In developing a chemotherapeutic program for children with disseminated neuroblastoma, we established three human neuroblastoma lines in cell culture to study the effects of dibutyryl cyclic AMP, papaverine, 5-trifluoromethyl-2'-deoxyuridine, and cyclophosphamide on cell growth, biochemical behavior, and morphology." | 3.65 | A rationale for the treatment of metastatic neuroblastoma. ( Das, SK; Helson, C; Helson, L; Peterson, RF, 1976) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Helson, L | 1 |
| Helson, C | 1 |
| Peterson, RF | 1 |
| Das, SK | 1 |
| Wajsman, Z | 1 |
| Williams, P | 1 |
| Murphy, GP | 1 |
2 other studies available for papaverine and Metastase
| Article | Year |
|---|---|
A rationale for the treatment of metastatic neuroblastoma.
Topics: Antineoplastic Agents; Bucladesine; Child; Child, Preschool; Cyclophosphamide; Drug Therapy, Combina | 1976 |
A study of the effect of papaverine in neuroblastoma using the experimental C1300 murine system.
Topics: Animals; Drug Evaluation, Preclinical; Mice; Mice, Inbred A; Neoplasm Metastasis; Neoplasms, Experim | 1978 |