papaverine has been researched along with Metaplasia in 4 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Metaplasia: A condition in which there is a change of one adult cell type to another similar adult cell type.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the second course, the mixture of dibutyryl cyclic AMP, prostaglandins E1, E2 and B1, and papaverine brings about an extensive squamous metaplasia and excessive keratinization." | 3.66 | Induction of squamous metaplasia: requirement for cell multiplication, and competition with lobuloalveolar development in cultured mammary glands. ( Custer, RP; Schaefer, FV; Sorof, S, 1983) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Schaefer, FV | 4 |
| Custer, RP | 4 |
| Sorof, S | 4 |
4 other studies available for papaverine and Metaplasia
| Article | Year |
|---|---|
Induction of abnormal development and differentiation in cultured mammary glands by cyclic adenine nucleotide and prostaglandins.
Topics: Animals; Bucladesine; Cell Differentiation; Epidermis; Female; Keratins; Mammary Glands, Animal; Mam | 1980 |
General process of induction of squamous metaplasia by cyclic adenine nucleotide and prostaglandins: mouse prostate glands.
Topics: Animals; Bucladesine; Culture Techniques; Drug Synergism; Epithelium; Keratins; Male; Metaplasia; Me | 1982 |
Induction of squamous metaplasia: requirement for cell multiplication, and competition with lobuloalveolar development in cultured mammary glands.
Topics: Animals; Bucladesine; Cell Differentiation; Cell Division; Epithelial Cells; Female; Mammary Glands, | 1983 |
Induction of epidermoid differentiation by cyclic adenine nucleotide in cultured mammary tumors of mice.
Topics: Adenocarcinoma; Animals; Bucladesine; Carcinoma, Squamous Cell; Cells, Cultured; Female; Mammary Gla | 1985 |