papaverine has been researched along with Metabolic Acidosis in 7 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 61-year-old female developed severe lactic acidosis after ingesting approximately 15 g of papaverine." | 7.66 | Lactic acidosis, a complication of papaverine overdose. ( Stokes, J; Treadwell, TR; Vaziri, ND, 1981) |
| "A 61-year-old female developed severe lactic acidosis after ingesting approximately 15 g of papaverine." | 3.66 | Lactic acidosis, a complication of papaverine overdose. ( Stokes, J; Treadwell, TR; Vaziri, ND, 1981) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (85.71) | 18.7374 |
| 1990's | 1 (14.29) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ZIELINSKI, J | 1 |
| KOZIOROWSKI, A | 1 |
| Janczewska, H | 1 |
| Vaziri, ND | 1 |
| Stokes, J | 1 |
| Treadwell, TR | 1 |
| McLoughlin, AL | 1 |
| Hjemdahl, P | 1 |
| Fredholm, BB | 1 |
| Montastruc, JL | 1 |
| Cotonat, J | 1 |
| Andrieu, M | 1 |
| Kaiser, D | 1 |
| Nadjafian, C | 1 |
| Werner, E | 1 |
7 other studies available for papaverine and Metabolic Acidosis
| Article | Year |
|---|---|
COMBINED RESPIRATORY AND METABOLIC ACIDOSIS CAUSED BY BRONCHOSPASM IN ANAPHYLACTIC SHOCK.
Topics: Acidosis; Acidosis, Respiratory; Aminopyrine; Anaphylaxis; Bronchial Spasm; Bronchodilator Agents; D | 1964 |
[Effect of metabolic acidosis on the action of hypotensive substances].
Topics: Acetylcholine; Acidosis; Animals; Cats; Histamine; Hypertension; Infusions, Parenteral; Lactates; Pa | 1967 |
Lactic acidosis, a complication of papaverine overdose.
Topics: Acidosis; Female; Humans; Lactates; Middle Aged; Papaverine | 1981 |
Intracisternal papaverine administration associated with acute onset of hyperthermia and metabolic acidosis in a craniotomy.
Topics: Acidosis; Adult; Angioplasty; Carotid Arteries; Cerebral Angiography; Cerebral Arteries; Cerebral In | 1997 |
Cyclic AMP-dependent and independent inhibition of lipolysis by adenosine and decreased pH.
Topics: Acidosis; Adenosine; Adenosine Deaminase; Animals; Cyclic AMP; Drug Interactions; Glycerol; Hydrogen | 1976 |
Effect of variations of blood pH on the haemodynamic actions of papaverine.
Topics: Acidosis; Alkalosis; Animals; Blood Physiological Phenomena; Cardiac Output; Dogs; Female; Heart Rat | 1978 |
[Effect of Perphyllon A on gas exchange, energy balance and peripheral oxygen supply of the newborn].
Topics: Acidosis; Humans; Hypercapnia; Infant, Newborn; Infant, Newborn, Diseases; Lactates; Oxygen Consumpt | 1969 |