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papaverine and Mental Disorders

papaverine has been researched along with Mental Disorders in 10 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Mental Disorders: Psychiatric illness or diseases manifested by breakdowns in the adaptational process expressed primarily as abnormalities of thought, feeling, and behavior producing either distress or impairment of function.

Research Excerpts

ExcerptRelevanceReference
"As far as the head pain was concerned, the feeling of giddiness, congestion in the head, rapid exhaustion, above all, tinnitus, responded best to the medication (the improvement amounting to approximately 40%), whereas of the mental complaints, a feeling of being "lost" or "abandoned" and a morose mood were most amenable to improvement (degree of improvement approximately 30%)."1.26[Eutergin in the treatment of chronic cerebrovascular disturbance patterns (author's transl)]. ( Prosenz, P, 1980)

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19909 (90.00)18.7374
1990's1 (10.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Prosenz, P1
Wittenborn, JR1
Pala, A1
Alleva, PM1
Tamura, M1
Iriguchi, H1
Miyamoto, T1
Kimura, K1
Kawanishi, Y1
Numata, A1
Yuasa, M1
Kagawa, S1
Petrie, WM1
Ban, TA1
Cacciatori, D1
Nelson, JJ1
Branconnier, RJ1
Cole, JO2
Stotsky, BA1
LaBrecque, DC1

Reviews

2 reviews available for papaverine and Mental Disorders

ArticleYear
Pharmacotherapy for age-related behavioral deficiencies.
    The Journal of nervous and mental disease, 1981, Volume: 169, Issue:3

    Topics: Adult; Aged; Aging; Anti-Anxiety Agents; Antidepressive Agents; Antipsychotic Agents; Brain; Central

1981
Drugs in geropsychiatry.
    Psychopharmacology bulletin, 1978, Volume: 14, Issue:4

    Topics: Aged; Anticoagulants; Central Nervous System Agents; Dementia; Dihydroergotoxine; Humans; Hypnotics

1978

Trials

1 trial available for papaverine and Mental Disorders

ArticleYear
Relieving select symptoms of the elderly.
    Geriatrics, 1975, Volume: 30, Issue:3

    Topics: Age Factors; Aged; Anxiety Disorders; Attitude; Brain; Clinical Trials as Topic; Dementia; Dihydroer

1975

Other Studies

7 other studies available for papaverine and Mental Disorders

ArticleYear
[Eutergin in the treatment of chronic cerebrovascular disturbance patterns (author's transl)].
    Aktuelle Gerontologie, 1980, Volume: 10, Issue:6

    Topics: Aged; Antidepressive Agents; Cerebrovascular Disorders; Chronic Disease; Dementia; Dihydroergotoxine

1980
[Papaveroline in mental disorders caused by a deficit of non-focalized cerebral circulation].
    La Clinica terapeutica, 1981, Jan-15, Volume: 96, Issue:1

    Topics: Adult; Aged; Cerebrovascular Disorders; Female; Humans; Male; Mental Disorders; Middle Aged; Papaver

1981
[Transition of diagnosis and treatment for impotence].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1993, Volume: 84, Issue:8

    Topics: Adolescent; Adult; Aged; Counseling; Diabetes Complications; Erectile Dysfunction; Humans; Ligation;

1993
[Experience with the combination of vincamine and papaverine in chronic brain syndrome].
    La Clinica terapeutica, 1979, Jun-15, Volume: 89, Issue:5

    Topics: Aged; Brain Ischemia; Cerebrovascular Disorders; Chronic Disease; Drug Therapy, Combination; Female;

1979
Effects of chronic papaverine administration on mild senile organic brain syndrome.
    Journal of the American Geriatrics Society, 1977, Volume: 25, Issue:10

    Topics: Aged; Dopamine Antagonists; Double-Blind Method; Female; Humans; Male; Mental Disorders; Middle Aged

1977
Improving psychiatric drug therapy. A matter of dosage and choice.
    Geriatrics, 1974, Volume: 29, Issue:6

    Topics: Adrenal Cortex Hormones; Adult; Aged; Anticoagulants; Antidepressive Agents; Antiparkinson Agents; B

1974
Papaverine hydrochloride as therapy for mentally confused geriatric patients.
    Current therapeutic research, clinical and experimental, 1966, Volume: 8, Issue:3

    Topics: Aged; Humans; Intracranial Arteriosclerosis; Male; Mental Disorders; Middle Aged; Papaverine

1966