papaverine has been researched along with MS (Multiple Sclerosis) in 9 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Using papaverine, papaverine/phentolamine, or prostaglandin E1 (PGE1), intracavernosal pharmacotherapy has been successful in treating erectile dysfunction." | 3.69 | Experience with intracavernosal tri-mixture for the management of neurogenic erectile dysfunction. ( Chao, R; Clowers, DE, 1994) |
| "Intracavernous injection of papaverine was tested in a group of 29 patients with multiple sclerosis and erectile dysfunction." | 3.67 | Pharmacologically induced erection in patients with multiple sclerosis. ( Kirkeby, HJ; Petersen, T; Poulsen, EU, 1988) |
| "All of the men with impotence and marked pyramidal dysfunction in their legs were found by cystometric studies to have bladder hyperreflexia." | 1.29 | Erectile dysfunction in multiple sclerosis. Associated neurological and neurophysiological deficits, and treatment of the condition. ( Betts, CD; Fowler, CG; Fowler, CJ; Jones, SJ, 1994) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (33.33) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sunke, R | 1 |
| Bankala, R | 1 |
| Thirupataiah, B | 1 |
| Ramarao, EVVS | 1 |
| Kumar, JS | 1 |
| Doss, HM | 1 |
| Medishetti, R | 1 |
| Kulkarni, P | 1 |
| Kapavarapu, RK | 1 |
| Rasool, M | 1 |
| Mudgal, J | 1 |
| Mathew, JE | 1 |
| Shenoy, GG | 1 |
| Parsa, KVL | 1 |
| Pal, M | 1 |
| Betts, CD | 1 |
| Jones, SJ | 1 |
| Fowler, CG | 1 |
| Fowler, CJ | 1 |
| Chao, R | 1 |
| Clowers, DE | 1 |
| Yoshikawa, M | 1 |
| Suzumura, A | 1 |
| Tamaru, T | 1 |
| Takayanagi, T | 1 |
| Sawada, M | 1 |
| Puolakka, VM | 1 |
| Hashmat, AI | 1 |
| Abrahams, J | 1 |
| Fani, K | 1 |
| Nostrand, I | 1 |
| Kirkeby, HJ | 2 |
| Petersen, T | 2 |
| Poulsen, EU | 2 |
| Dørup, J | 1 |
| Baskett, PJ | 1 |
| Armstrong, R | 1 |
1 review available for papaverine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
[Bladder dysfunction and sexual dysfunction and their management in patients with MS disease].
Topics: Alprostadil; Erectile Dysfunction; Female; Humans; Male; Multiple Sclerosis; Papaverine; Sexual Dysf | 1992 |
8 other studies available for papaverine and MS (Multiple Sclerosis)
| Article | Year |
|---|---|
InCl
Topics: Animals; Arthritis; Cyclic Nucleotide Phosphodiesterases, Type 4; Encephalomyelitis, Autoimmune, Exp | 2019 |
Erectile dysfunction in multiple sclerosis. Associated neurological and neurophysiological deficits, and treatment of the condition.
Topics: Adult; Brain Mapping; Ejaculation; Erectile Dysfunction; Evoked Potentials; Humans; Leg; Male; Middl | 1994 |
Experience with intracavernosal tri-mixture for the management of neurogenic erectile dysfunction.
Topics: Adult; Alprostadil; Cost-Benefit Analysis; Drug Combinations; Drug Costs; Drug Monitoring; Drug Syne | 1994 |
Effects of phosphodiesterase inhibitors on cytokine production by microglia.
Topics: 1-Methyl-3-isobutylxanthine; Amrinone; Animals; Anti-Ulcer Agents; Cilostazol; Colforsin; Dipyridamo | 1999 |
A lethal complication of papaverine-induced priapism.
Topics: Dose-Response Relationship, Drug; Humans; Male; Middle Aged; Multiple Sclerosis; Papaverine; Penis; | 1991 |
Pharmacologically induced erection in patients with multiple sclerosis.
Topics: Adult; Humans; Injections; Male; Middle Aged; Multiple Sclerosis; Papaverine; Penile Erection; Self | 1988 |
Erectile dysfunction in multiple sclerosis.
Topics: Adult; Erectile Dysfunction; Evoked Potentials; Humans; Male; Middle Aged; Multiple Sclerosis; Papav | 1988 |
Anaesthetic problems in multiple sclerosis. Are certain agents contraindicated?
Topics: Adult; Amobarbital; Anesthesia; Anesthetics; Atropine; Female; Halothane; Humans; Levallorphan; Mepe | 1970 |