Page last updated: 2024-11-02

papaverine and Labor Pain

papaverine has been researched along with Labor Pain in 3 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Labor Pain: Pain associated with OBSTETRIC LABOR in CHILDBIRTH. It is caused primarily by UTERINE CONTRACTION as well as pressure on the CERVIX; BLADDER; and the GASTROINTESTINAL TRACT. Labor pain mostly occurs in the ABDOMEN; the GROIN; and the BACK.

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19901 (33.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (33.33)24.3611
2020's1 (33.33)2.80

Authors

AuthorsStudies
Ikeotuonye, AC1
Umeora, OJ1
Nwafor, JI1
Ojumah, BO1
Ekwunife, IC1
Dimejesi, IB1
Ibrahim, MI1
Alzeeniny, HA1
Ellaithy, MI1
Salama, AH1
Abdellatif, MA1
RIEGER, H1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Effect of IV PAPAVERINE 80 mg Prior to Catheter Balloon Insertion on Bishop Score and Pain, Double Blinded Randomized Placebo Controlled Trial[NCT05759364]128 participants (Anticipated)Interventional2023-05-15Recruiting
Use of Antispasmodic Drotaverine to Shorten the Length of Labor in Nulliparous Women[NCT01639027]Phase 2/Phase 3352 participants (Actual)Interventional2012-05-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

2 trials available for papaverine and Labor Pain

ArticleYear
Drotaverine to shorten the duration of labour in primigravidas: a randomised, double-blind, placebo-controlled trial.
    African health sciences, 2022, Volume: 22, Issue:3

    Topics: Double-Blind Method; Female; Humans; Infant, Newborn; Labor Pain; Labor, Obstetric; Oxytocin; Papave

2022
Drotaverine to improve progression of labor among nulliparous women.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2014, Volume: 124, Issue:2

    Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; P

2014
Drotaverine to improve progression of labor among nulliparous women.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2014, Volume: 124, Issue:2

    Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; P

2014
Drotaverine to improve progression of labor among nulliparous women.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2014, Volume: 124, Issue:2

    Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; P

2014
Drotaverine to improve progression of labor among nulliparous women.
    International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2014, Volume: 124, Issue:2

    Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; P

2014

Other Studies

1 other study available for papaverine and Labor Pain

ArticleYear
[Safe mitigation of labor pain by belladonna-exclud suppository].
    Die Medizinische, 1955, Aug-20, Issue:33-34

    Topics: Aminopyrine; Analgesia; Anesthesia; Anesthesia and Analgesia; Atropa belladonna; Barbiturates; Femal

1955