papaverine has been researched along with Labor Pain in 3 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Labor Pain: Pain associated with OBSTETRIC LABOR in CHILDBIRTH. It is caused primarily by UTERINE CONTRACTION as well as pressure on the CERVIX; BLADDER; and the GASTROINTESTINAL TRACT. Labor pain mostly occurs in the ABDOMEN; the GROIN; and the BACK.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 1 (33.33) | 2.80 |
| Authors | Studies |
|---|---|
| Ikeotuonye, AC | 1 |
| Umeora, OJ | 1 |
| Nwafor, JI | 1 |
| Ojumah, BO | 1 |
| Ekwunife, IC | 1 |
| Dimejesi, IB | 1 |
| Ibrahim, MI | 1 |
| Alzeeniny, HA | 1 |
| Ellaithy, MI | 1 |
| Salama, AH | 1 |
| Abdellatif, MA | 1 |
| RIEGER, H | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of IV PAPAVERINE 80 mg Prior to Catheter Balloon Insertion on Bishop Score and Pain, Double Blinded Randomized Placebo Controlled Trial[NCT05759364] | 128 participants (Anticipated) | Interventional | 2023-05-15 | Recruiting | |||
| Use of Antispasmodic Drotaverine to Shorten the Length of Labor in Nulliparous Women[NCT01639027] | Phase 2/Phase 3 | 352 participants (Actual) | Interventional | 2012-05-31 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 trials available for papaverine and Labor Pain
| Article | Year |
|---|---|
Drotaverine to shorten the duration of labour in primigravidas: a randomised, double-blind, placebo-controlled trial.
Topics: Double-Blind Method; Female; Humans; Infant, Newborn; Labor Pain; Labor, Obstetric; Oxytocin; Papave | 2022 |
Drotaverine to improve progression of labor among nulliparous women.
Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; P | 2014 |
Drotaverine to improve progression of labor among nulliparous women.
Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; P | 2014 |
Drotaverine to improve progression of labor among nulliparous women.
Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; P | 2014 |
Drotaverine to improve progression of labor among nulliparous women.
Topics: Adult; Double-Blind Method; Female; Humans; Kaplan-Meier Estimate; Labor Pain; Labor Stage, First; P | 2014 |
1 other study available for papaverine and Labor Pain
| Article | Year |
|---|---|
[Safe mitigation of labor pain by belladonna-exclud suppository].
Topics: Aminopyrine; Analgesia; Anesthesia; Anesthesia and Analgesia; Atropa belladonna; Barbiturates; Femal | 1955 |