papaverine has been researched along with Kidney Diseases in 13 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Kidney Diseases: Pathological processes of the KIDNEY or its component tissues.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Papaverine was topically applied on the renal arteries resulting in vasodilation and reperfusion of the kidney." | 6.58 | Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy. ( Cadeddu, JA; Sorokin, I; Stevens, SL, 2018) |
| "Papaverine hydrochloride was as effective as sodium diclofenac in alleviating pain and the combined treatment group showed a slight trend of more rapid relief." | 2.73 | Papaverine hydrochloride for the treatment of renal colic: an old drug revisited. A prospective, randomized study. ( Lifshitz, DA; Livne, PM; Margel, D; Moskovitz, B; Nativ, O; Sandovski, U; Snir, N; Sulkes, J, 2008) |
| "Papaverine was topically applied on the renal arteries resulting in vasodilation and reperfusion of the kidney." | 2.58 | Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy. ( Cadeddu, JA; Sorokin, I; Stevens, SL, 2018) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (76.92) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (15.38) | 29.6817 |
| 2010's | 1 (7.69) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sorokin, I | 1 |
| Stevens, SL | 1 |
| Cadeddu, JA | 1 |
| Garmish, OS | 1 |
| Zabashnyĭ, SI | 1 |
| Smirnova, EV | 1 |
| Kobeliatskiĭ, IuIu | 1 |
| JOHNSTONE, PN | 1 |
| STONE, RG | 1 |
| BURDICK, HC | 1 |
| ALLEBACH, HK | 1 |
| PATTON, LF | 1 |
| TULLER, FE | 1 |
| ERB, LE | 1 |
| RUTISHAUSER, G | 1 |
| Snir, N | 1 |
| Moskovitz, B | 1 |
| Nativ, O | 1 |
| Margel, D | 1 |
| Sandovski, U | 1 |
| Sulkes, J | 1 |
| Livne, PM | 1 |
| Lifshitz, DA | 1 |
| Lundstam, SO | 1 |
| Leissner, KH | 1 |
| Wåhlander, LA | 1 |
| Kral, JG | 1 |
| Büchner, SA | 1 |
| Meier-Ruge, W | 1 |
| Jönsson, PE | 1 |
| Olsson, AM | 1 |
| Petersson, BA | 1 |
| Johansson, K | 1 |
| Port, FK | 1 |
| Fiegel, P | 1 |
| Hecking, E | 1 |
| Köhler, H | 1 |
| Distler, A | 1 |
| Klemm, J | 1 |
| Ifrim, M | 1 |
| Sálájan, V | 1 |
| Wright, HK | 1 |
| Gann, DS | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| The Effect of IV PAPAVERINE 80 mg Prior to Catheter Balloon Insertion on Bishop Score and Pain, Double Blinded Randomized Placebo Controlled Trial[NCT05759364] | 128 participants (Anticipated) | Interventional | 2023-05-15 | Recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
2 reviews available for papaverine and Kidney Diseases
| Article | Year |
|---|---|
Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy.
Topics: Adult; Humans; Intraoperative Complications; Ischemia; Kidney; Kidney Diseases; Male; Nephrectomy; P | 2018 |
NSAIDS for renal and biliary colic: intramuscular diclofenac.
Topics: Anti-Inflammatory Agents, Non-Steroidal; Biliary Tract Diseases; Codeine; Colic; Diclofenac; Drug Co | 1987 |
4 trials available for papaverine and Kidney Diseases
| Article | Year |
|---|---|
[Preparation no-shpa forte for the treatment of renal colic].
Topics: Adult; Aged; Colic; Female; Hemodynamics; Humans; Kidney Diseases; Male; Middle Aged; Papaverine; Pa | 2003 |
Papaverine hydrochloride for the treatment of renal colic: an old drug revisited. A prospective, randomized study.
Topics: Adult; Anti-Inflammatory Agents, Non-Steroidal; Colic; Diclofenac; Drug Therapy, Combination; Female | 2008 |
Prostaglandin-synthetase inhibition with diclofenac sodium in treatment of renal colic: comparison with use of a narcotic analgesic.
Topics: Adolescent; Adult; Aged; Analgesics, Opioid; Codeine; Colic; Cyclooxygenase Inhibitors; Diclofenac; | 1982 |
Intravenous indomethacin and oxycone-papaverine in the treatment of acute renal colic. A double-blind study.
Topics: Acute Disease; Adult; Aged; Clinical Trials as Topic; Codeine; Colic; Double-Blind Method; Drug Comb | 1987 |
7 other studies available for papaverine and Kidney Diseases
| Article | Year |
|---|---|
Studies on the etiology and treatment of acute renal failure.
Topics: Acute Kidney Injury; Heart, Artificial; Humans; Kidney Diseases; Papaverine | 1956 |
[On the pathogenesis of ureteral colic].
Topics: Humans; Kidney Diseases; Papaverine; Renal Colic; Ureteral Obstruction | 1962 |
The significance of the hairpin counter-current principle in the pathogenesis of toxic kidney lesions. An investigation of the influence of antidiuretic hormone and papaverine on hydroxyquinoline nephropathy of the rat.
Topics: Alkaline Phosphatase; Animals; Esterases; Female; Histocytochemistry; Hydroxyquinolines; Kidney; Kid | 1977 |
Priapism during regular haemodialysis.
Topics: Adult; Chronic Disease; Diazepam; Glomerulonephritis; Heparin; Home Care Services; Humans; Infusions | 1974 |
[Premedication in x-ray contrast pictures of the gallbladder and kidney].
Topics: Amylases; Aspergillus; Cholangiography; Cholecystography; Humans; Kidney Diseases; Papaverine; Pepti | 1973 |
[Correlation between pregnancy complications and congenital malformations in the newborn infant].
Topics: Abnormalities, Drug-Induced; Carbohydrate Metabolism; Congenital Abnormalities; Drug-Related Side Ef | 1973 |
Extension of renal autoregulation during hemorrhage by mannitol.
Topics: Animals; Dogs; Hemorrhage; Kidney Diseases; Mannitol; Papaverine; Vasomotor System | 1965 |