Page last updated: 2024-11-02

papaverine and Ischemia

papaverine has been researched along with Ischemia in 99 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"To analyze the predictive factors causing ischemic priapism following penile doppler ultrasonography (PDU) with intracavernosal papaverine injection   Materials and methods: Medical records of 467 patients who underwent PDU examination following intracavernosal papaverine injection for erectile dysfunction (ED) between 2009 and 2017 were retrospectively reviewed."7.96Independent Predictive Factors for Occurrence of Ischemic Priapism after Papaverine Injection. ( Erbin, A; Güler, Y, 2020)
"Papaverine was topically applied on the renal arteries resulting in vasodilation and reperfusion of the kidney."6.58Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy. ( Cadeddu, JA; Sorokin, I; Stevens, SL, 2018)
" A total of 400 patients with erectile dysfunction were evaluated before and after diagnostic intracavernous injection of a trimix solution (papaverine+phentolamine+PGE1) using color Doppler sonography."5.11The value of penile duplex in the prediction of intracavernous drug-induced priapism. ( Ghanem, HM; Kamel, II; Mousa, AA; Salem, A; Shamloul, R, 2004)
"To analyze the predictive factors causing ischemic priapism following penile doppler ultrasonography (PDU) with intracavernosal papaverine injection   Materials and methods: Medical records of 467 patients who underwent PDU examination following intracavernosal papaverine injection for erectile dysfunction (ED) between 2009 and 2017 were retrospectively reviewed."3.96Independent Predictive Factors for Occurrence of Ischemic Priapism after Papaverine Injection. ( Erbin, A; Güler, Y, 2020)
" Using an ischemic ventral pedicled island cutaneous flap model, 30 adult Sprague-Dawley rats were divided into groups and treated with BTX, papaverine, or saline to the intact vascular pedicle to determine the percentage of tissue necrosis and ischemia."3.75Effects of perivascular Botulinum Toxin-A application on vascular smooth muscle and flap viability in the rat. ( Arnold, PB; Campbell, CA; Drake, DB; Merritt, W; Morgan, RF; Rodeheaver, GT, 2009)
"We present the case of an 83-year-old patient who underwent cardiac surgery and developed postoperative non-occlusive mesenteric ischemia (NOMI), which was treated with a local intra-arterial papaverine and prostaglandin E1 infusion."3.73Vasopressin as adjunct vasopressor for vasodilatory shock due to non-occlusive mesenteric ischemia. ( Dünser, MW; Friesenecker, B; Jochberger, S; Knotzer, H; Lorenz, I; Luckner, G; Mayr, VD; Pajk, W; Wenzel, V, 2006)
" The additional use of collagenase, papaverine and ischemia raised expression moderately but was not critical."3.70The efficient expression of intravascularly delivered DNA in rat muscle. ( Budker, V; Danko, I; Williams, P; Wolff, J; Zhang, G, 1998)
" Despite cessation of heparin-dihydroergotamine and infusion of intraarterial papaverine into the right femoral artery, both lower extremities progressed to frank gangrene and amputation (above-knee on the left and below-knee on the right)."3.68St. Anthony's fire: successful reversal of ergotamine-induced peripheral vasospasm by hydrostatic dilatation. ( Baader, W; Herman, C; Johansen, K, 1990)
"We have previously described a technique for intrathecal administration of papaverine and cerebrospinal fluid drainage to prevent paraplegia after aortic surgery."3.68Appraisal of cerebrospinal fluid alterations during aortic surgery with intrathecal papaverine administration and cerebrospinal fluid drainage. ( Bednarski, M; Cosgrove, DM; Grum, DF; Loop, FD; Svensson, LG, 1990)
"The anti-hypoxic effect of cinnarizine was studied using the following experimental methods: hypobaric and anoxic hypoxia in mice, complete ischemia by decapitation in mice and hemic hypoxia in rats."3.67Study on the anti-hypoxic effect of cinnarizine and its interaction with prostacyclin. ( Milanova, D; Nikolov, R; Nikolova, M, 1984)
"A patient with a clinical and angiographic diagnosis of nonocclusive mesenteric ischemia had phenoxybenzamine directly infused into the superior mesenteric artery to counteract the existing splanchnic vasoconstriction."3.65Vasodilatory drugs in the management of nonocclusive bowel ischemia. ( Athanasoulis, CA; Bernstein, R; Williams, LF; Wittenberg, J, 1975)
"Papaverine was topically applied on the renal arteries resulting in vasodilation and reperfusion of the kidney."2.58Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy. ( Cadeddu, JA; Sorokin, I; Stevens, SL, 2018)
"Acute bowel ischemia is a rare but often catastrophic event after coronary bypass surgery."1.31Acute bowel ischemia after coronary bypass surgery--a catastrophic event. ( Caleb, MG, 2001)
"Nicardipine was greater than papaverine in inducing relaxation."1.30Drug-induced vasodilation in an in vitro and in vivo study: the effects of nicardipine, papaverine, and lidocaine on the rabbit carotid artery. ( Cromeens, DM; Evans, GR; Gherardini, G; Gürlek, A; Joly, GA; Kilbourn, RG; Langstein, H; Lundeberg, T; Sukumaran, AV; Wang, B; Williams, J, 1997)
"Acute mesenteric ischemia is a rare and often fatal event after cardiopulmonary bypass."1.29Mesenteric ischemia after a cardiac operation: conservative treatment with local vasodilation. ( Brühlmann, W; Genoni, M; Niederhäuser, U; Turina, MI; von Segesser, LK, 1996)
"Ischemia was induced by clamping of the renal artery, or of the renal artery and vein, in situ."1.26Vascular resistance in hypothermically perfused kidneys damaged by warm ischemia. ( Bilde, T, 1976)
"Following normothermic cardiac arrest an increase of the coronary resistance and a decrease of the cross section of the coronary arteries have been measured as a function of the duration of the ischaemic period during intermittent coronary perfusion."1.25[Effect of coronary vasodilator agents on the increase of coronary resistance during ischemia]. ( Böttcher, H; Schäfer, W, 1975)

Research

Studies (99)

TimeframeStudies, this research(%)All Research%
pre-199052 (52.53)18.7374
1990's24 (24.24)18.2507
2000's14 (14.14)29.6817
2010's8 (8.08)24.3611
2020's1 (1.01)2.80

Authors

AuthorsStudies
Güler, Y1
Erbin, A1
Sorokin, I1
Stevens, SL1
Cadeddu, JA1
Ruzsa, Z1
Róna, S1
Tóth, GG1
Sótonyi, P1
Bertrand, OF1
Nemes, B1
Merkely, B1
Hüttl, K1
Ricci, JA1
Singhal, D1
Fukudome, EY1
Tobias, AM1
Lin, SJ1
Lee, BT1
Mazzei, MA1
Guerrini, S1
Cioffi Squitieri, N1
Imbriaco, G1
Mazzei, FG1
Volterrani, L1
Tkachuk, OL1
Gudz, OI1
Panigrahy, N1
Kumar, PP1
Chirla, DK1
Vennapusa, SR1
Arnold, PB1
Merritt, W1
Rodeheaver, GT1
Campbell, CA1
Morgan, RF1
Drake, DB1
Kazui, T1
Yamasaki, M1
Abe, K1
Watanabe, S1
Kawazoe, K1
Khan, SN1
Stansby, G1
Bittner, Ch1
Zuber, M1
Eisner, L1
Zacherl, J2
Thein, E1
Stangl, M2
Feussner, H2
Bock, S2
Mittlböck, M1
Erhardt, W2
Siewert, JR2
Krämer, SC1
Görich, J1
Oertel, F1
Scheld, H1
Heindel, W1
Shamloul, R1
Ghanem, HM1
Salem, A1
Kamel, II1
Mousa, AA1
Luckner, G1
Jochberger, S1
Mayr, VD1
Knotzer, H1
Pajk, W1
Wenzel, V1
Friesenecker, B1
Lorenz, I1
Dünser, MW1
Bozlar, U1
Turba, UC1
Hagspiel, KD1
Ermolaev, VL2
Burleva, EP1
Nikolov, R1
Nikolova, M1
Milanova, D1
Nielsen, HV1
Boley, SJ6
Feinstein, FR1
Sammartano, R1
Brandt, LJ2
Sprayregen, S4
Williams, RA2
Wilson, SE2
Makarova, NP1
Zavalskiĭ, II1
Bauters, C1
Asahara, T1
Zheng, LP1
Takeshita, S1
Bunting, S1
Ferrara, N1
Symes, JF1
Isner, JM1
Schneider, TA1
Longo, WE1
Ure, T1
Vernava, AM1
Pereira, AH1
Cutin, J1
Eggers, E1
Alós, R1
Garcia-Granero, E1
Calvete, J1
Uribe, N1
Ito, M1
Shichijo, K1
Sekine, I1
Dunn, MM1
McFall, TA1
Rigano, WD1
Peoples, JB1
Niederhäuser, U1
Genoni, M2
von Segesser, LK1
Brühlmann, W2
Turina, MI2
Evans, GR1
Gherardini, G1
Gürlek, A1
Langstein, H1
Joly, GA1
Cromeens, DM1
Sukumaran, AV1
Williams, J1
Kilbourn, RG1
Wang, B1
Lundeberg, T1
Budker, V1
Zhang, G1
Danko, I1
Williams, P1
Wolff, J1
Tang, AT1
Hooper, TL1
Sun, J1
Hirsch, D1
Svensson, G1
D'Amore, MJ1
Borge, MA1
Messersmith, RN1
Eker, A1
Malzac, B1
Teboul, J1
Jourdan, J1
Svensson, LG2
Arquilla, B1
Gupta, R1
Gernshiemer, J1
Fischer, M1
Dreier, JP1
Petzold, G1
Tille, K1
Lindauer, U1
Arnold, G1
Heinemann, U1
Einhäupl, KM1
Dirnagl, U1
Caleb, MG1
Klotz, S1
Vestring, T1
Rötker, J1
Schmidt, C1
Scheld, HH1
Schmid, C1
Biraima, AM1
Winkler, MB1
Karimov, ZZ1
Bakhritdinov, FSh1
Trynkin, AV1
Bookstein, JJ1
Goldberger, L1
Niwayama, G1
Naderi, MJ1
Brahme, FJ1
Jones, TA1
Valido, A1
Lopez-Novoa, JM2
Hernando, L2
Gygax, P1
Hunziker, O1
Schulz, U1
Schweizer, A1
Schäfer, W1
Böttcher, H1
Parker, PE1
Bashour, FA1
Downey, HF1
Boutros, IS1
Sprayregan, S1
Siegelman, SS3
Veith, FJ2
Coffman, JD2
Athanasoulis, CA1
Wittenberg, J1
Bernstein, R1
Williams, LF1
Bünger, R1
Haddy, FJ1
Querengässer, A1
Gerlach, E1
Bilde, T3
Davies, AH2
Magee, TR1
Baird, RN1
Horrocks, M2
Cooper, GG2
Bakal, CW1
Wolf, EL1
Galt, SW1
Cronenwett, JL1
Hood, JM1
Barros D'Sa, AA1
Baader, W1
Herman, C1
Johansen, K1
Grum, DF1
Bednarski, M1
Cosgrove, DM1
Loop, FD1
Valentine, RJ1
Whelan, TV1
Meyers, HF1
Chaudry, IH1
Opie, JC1
Zavitzanos, J1
Bell-Thompson, J1
Baker, AR1
Macpherson, DS1
Evans, DH1
Bell, PR1
Zaritsky, A1
Pollak, S1
Frideman, P1
Swarts, Y1
MacCannell, KL1
Bulkley, GB1
Womack, WA1
Downey, JM1
Kvietys, PR1
Granger, DN1
Gearhart, JP1
Jeffs, RD1
Hahn, N1
Felix, R1
Richards, A1
Wright, J1
Balcon, R1
Almici, C1
Lazzaroni, G1
Yao, JS1
Bergan, JJ1
Grandchamp, A1
Ayer, G1
Truniger, B1
Besznyák, I1
Sebestény, M1
Nemes, A1
Rényi-Vámos, F1
Ancalmo, N1
Ochsner, JL1
Sharzer, LA1
Lawton, RL1
Heiss, WD1
Skagseth, E1
Hall, KV1
Long, JS1
Severs, WB1
Urdaneta, LF1
Gilsdorf, RB1
Leonard, AS1
Lokkegaard, H1
Appelgren, KL1
Bernhard, VM2
Ashmore, CS1
Rodgers, RE2
Evans, WE1
Stern, FH1
Prikryl, P1
Friedman, JJ1
Kayser, K1
Gutierrez, JE1
Wilson, SD1
Ellison, EH1
Serradimigni, A1
Bory, M1
Poggi, L1
Audier, M1
Tibbs, EE1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison Effect Between Lower Pressure and Standard Pressure Pneumoperitoneum on Sign of Acute Systemic Inflammation, Endothelial Injury, and Acute Kidney Injury: A Randomized Clinical Trial in Living Donor Laparoscopic Nephrectomy[NCT03219398]44 participants (Actual)Interventional2017-08-01Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

11 reviews available for papaverine and Ischemia

ArticleYear
Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy.
    Journal of robotic surgery, 2018, Volume: 12, Issue:1

    Topics: Adult; Humans; Intraoperative Complications; Ischemia; Kidney; Kidney Diseases; Male; Nephrectomy; P

2018
Cerebrospinal fluid drainage for thoracic and thoracoabdominal aortic aneurysm surgery.
    The Cochrane database of systematic reviews, 2012, Oct-17, Volume: 10

    Topics: Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Cerebrospinal Fluid; Cerebrospinal Fluid Pres

2012
[Non-occlusive mesenteric ischemia].
    RoFo : Fortschritte auf dem Gebiete der Rontgenstrahlen und der Nuklearmedizin, 2003, Volume: 175, Issue:9

    Topics: Abdominal Pain; Age Factors; Aged; Alprostadil; Angiography; Cardiac Surgical Procedures; Contraindi

2003
Mesenteric ischemia. Acute arterial syndromes.
    Diseases of the colon and rectum, 1994, Volume: 37, Issue:11

    Topics: Abdominal Pain; Acute Disease; Angiography; Diagnosis, Differential; Embolectomy; Gastric Emptying;

1994
Vasodilator drugs in peripheral vascular disease.
    The Journal of the Maine Medical Association, 1975, Volume: 66, Issue:10

    Topics: Animals; Arterial Occlusive Diseases; Cyclandelate; Ergot Alkaloids; Humans; Ischemia; Isoxsuprine;

1975
Vasodilator drugs in peripheral vascular disease.
    American journal of hospital pharmacy, 1975, Volume: 32, Issue:12

    Topics: Arterial Occlusive Diseases; Cyclandelate; Ergot Alkaloids; Ethanol; Guanethidine; Humans; Ischemia;

1975
Radiology in intestinal ischemia. Angiographic diagnosis and management.
    The Surgical clinics of North America, 1992, Volume: 72, Issue:1

    Topics: Angiography; Chronic Disease; Humans; Intestines; Ischemia; Mesenteric Arteries; Mesenteric Veins; P

1992
ATP-MgCl2 and liver blood flow following shock and ischemia.
    Progress in clinical and biological research, 1989, Volume: 299

    Topics: Adenosine Triphosphate; Animals; Dopamine; Ischemia; Ligation; Liver Circulation; Magnesium; Magnesi

1989
Pressure studies in arterial surgery.
    European journal of vascular surgery, 1987, Volume: 1, Issue:4

    Topics: Blood Pressure; Blood Pressure Determination; Hemodynamics; Humans; Intermittent Claudication; Ische

1987
Application of new techniques in blood flow measurement in patients with peripheral vascular problems.
    Surgery annual, 1974, Volume: 6

    Topics: Adult; Arterial Occlusive Diseases; Auscultation; Blood Circulation; Blood Pressure; Carotid Artery

1974
An aggressive roentgenologic and surgical approach to acute mesenteric ischemia.
    Surgery annual, 1973, Volume: 5

    Topics: Angiography; Blood Flow Velocity; Blood Pressure; Embolism; Humans; Infusions, Parenteral; Intestine

1973

Trials

3 trials available for papaverine and Ischemia

ArticleYear
The value of penile duplex in the prediction of intracavernous drug-induced priapism.
    International journal of impotence research, 2004, Volume: 16, Issue:1

    Topics: Alprostadil; Antihypertensive Agents; Erectile Dysfunction; Humans; Ischemia; Male; Middle Aged; Pap

2004
Diagnosis and treatment of nonocclusive mesenteric ischemia after open heart surgery.
    The Annals of thoracic surgery, 2001, Volume: 72, Issue:5

    Topics: Aged; Cardiac Surgical Procedures; Female; Humans; Infusions, Intra-Arterial; Ischemia; Male; Mesent

2001
Further evaluation of papaverine for peripheral vascular ischemia.
    Journal of the American Geriatrics Society, 1967, Volume: 15, Issue:4

    Topics: Aged; Clinical Trials as Topic; Diabetes Complications; Female; Humans; Intermittent Claudication; I

1967

Other Studies

85 other studies available for papaverine and Ischemia

ArticleYear
Independent Predictive Factors for Occurrence of Ischemic Priapism after Papaverine Injection.
    Urology journal, 2020, 05-28, Volume: 17, Issue:5

    Topics: Adult; Erectile Dysfunction; Humans; Injections, Intralesional; Ischemia; Male; Middle Aged; Papaver

2020
Fractional flow reserve in below the knee arteries with critical limb ischemia and validation against gold-standard morphologic, functional measures and long term clinical outcomes.
    Cardiovascular revascularization medicine : including molecular interventions, 2018, Volume: 19, Issue:2

    Topics: Aged; Angiography; Angioplasty, Balloon; Blood Pressure; Blood Pressure Determination; Critical Illn

2018
Topical nitroglycerin for the treatment of intraoperative microsurgical vasospasm.
    Microsurgery, 2018, Volume: 38, Issue:5

    Topics: Administration, Topical; Adult; Anastomosis, Surgical; Breast; Cohort Studies; Female; Follow-Up Stu

2018
Non-obstructive mesenteric ischemia after cardiovascular surgery: not so uncommon.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2014, Volume: 20, Issue:3

    Topics: Aortic Aneurysm, Abdominal; Blood Vessel Prosthesis Implantation; Coronary Artery Bypass; Female; Hu

2014
[APPLICATION OF LARGE SUBCUTANEOUS VEIN AS MATERIAL FOR DISTAL SHUNTING IN CRITICAL ISCHEMIA OF THE LOWER EXTREMITY TISSUES].
    Klinichna khirurhiia, 2015, Issue:4

    Topics: Aged; Female; Femoral Vein; Humans; Ischemia; Lower Extremity; Male; Middle Aged; Nitroglycerin; Pap

2015
Papaverine for Ischemia Following Peripheral Arterial Catheterization in Neonates.
    Indian pediatrics, 2016, Volume: 53, Issue:2

    Topics: Catheterization, Peripheral; Humans; Infant, Extremely Low Birth Weight; Infant, Newborn; Ischemia;

2016
Effects of perivascular Botulinum Toxin-A application on vascular smooth muscle and flap viability in the rat.
    Annals of plastic surgery, 2009, Volume: 62, Issue:5

    Topics: Animals; Botulinum Toxins, Type A; Ischemia; Muscle, Smooth, Vascular; Necrosis; Papaverine; Rats; R

2009
Non-obstructive mesenteric ischemia: a potentially lethal complication after cardiovascular surgery: report of two cases.
    Annals of thoracic and cardiovascular surgery : official journal of the Association of Thoracic and Cardiovascular Surgeons of Asia, 2012, Volume: 18, Issue:1

    Topics: Aged; Angiography; Aortic Aneurysm, Abdominal; Blood Vessel Prosthesis Implantation; Colectomy; Comb

2012
[Acute ischemia of the hand in a drug addict after accidental intra-arterial injection].
    Swiss surgery = Schweizer Chirurgie = Chirurgie suisse = Chirurgia svizzera, 2002, Volume: 8, Issue:6

    Topics: Adult; Bupivacaine; Compartment Syndromes; Fasciotomy; Hand; Heparin; Humans; Illicit Drugs; Injecti

2002
The influence of periarterial papaverine application on intraoperative renal function and blood flow during laparoscopic donor nephrectomy in a pig model.
    Surgical endoscopy, 2003, Volume: 17, Issue:8

    Topics: Animals; Creatinine; Diuresis; Drug Evaluation, Preclinical; Fluorescent Dyes; Injections; Ischemia;

2003
Periarterial application of papaverine during laparoscopic donor nephrectomy improves early graft function after kidney transplantation in pigs.
    Surgical endoscopy, 2004, Volume: 18, Issue:3

    Topics: Animals; Creatinine; Diuresis; Drug Evaluation, Preclinical; Graft Survival; Injections; Ischemia; K

2004
Vasopressin as adjunct vasopressor for vasodilatory shock due to non-occlusive mesenteric ischemia.
    Der Anaesthesist, 2006, Volume: 55, Issue:3

    Topics: Aged, 80 and over; Arginine Vasopressin; Atrial Fibrillation; Cardiac Surgical Procedures; Female; H

2006
Nonocclusive mesenteric ischemia: findings at multidetector CT angiography.
    Journal of vascular and interventional radiology : JVIR, 2007, Volume: 18, Issue:10

    Topics: Aged, 80 and over; Angiography, Digital Subtraction; Humans; Infusions, Intra-Arterial; Ischemia; Ma

2007
[Transcatheteral intra-arterial infusion of drug mixtures in the treatment of severe ischemia of the lower limbs].
    Vestnik khirurgii imeni I. I. Grekova, 1982, Volume: 129, Issue:11

    Topics: Acetylcholine; Adult; Aged; Catheterization; Dextrans; Diphenhydramine; Drug Combinations; Female; H

1982
Study on the anti-hypoxic effect of cinnarizine and its interaction with prostacyclin.
    Methods and findings in experimental and clinical pharmacology, 1984, Volume: 6, Issue:3

    Topics: Animals; Atmospheric Pressure; Brain; Cinnarizine; Drug Interactions; Epoprostenol; Hypoxia; Ischemi

1984
Arterial pressure-blood flow relations during limb elevation in man.
    Acta physiologica Scandinavica, 1983, Volume: 118, Issue:4

    Topics: Adult; Blood Pressure; Female; Homeostasis; Humans; Ischemia; Leg; Male; Muscle, Smooth, Vascular; M

1983
Early diagnosis of acute mesenteric ischemia.
    Hospital practice (Office ed.), 1981, Volume: 16, Issue:8

    Topics: Acute Disease; Constriction, Pathologic; Embolism; Gangrene; Humans; Intestines; Ischemia; Mesenteri

1981
New concepts in the management of emboli of the superior mesenteric artery.
    Surgery, gynecology & obstetrics, 1981, Volume: 153, Issue:4

    Topics: Aged; Embolism; Female; Humans; Infusions, Intra-Arterial; Intestines; Ischemia; Male; Mesenteric Ar

1981
Effect of intra-arterial vasodilators on blood flow in ischemic dog colon.
    Archives of surgery (Chicago, Ill. : 1960), 1980, Volume: 115, Issue:5

    Topics: Animals; Colon; Dogs; Female; Ischemia; Isoproterenol; Male; Mesenteric Arteries; Papaverine; Pulse;

1980
Radioxenon washout for evaluation of vasodilator therapy in mesenteric ischemia.
    The American journal of gastroenterology, 1980, Volume: 73, Issue:5

    Topics: Animals; Blood Flow Velocity; Colon; Dogs; Ischemia; Mesenteric Arteries; Papaverine; Time Factors;

1980
[Use of transcatheter intra-arterial infusion of drug mixtures in the combined treatment of patients with obliterating vascular diseases in the terminal stage of limb ischemia].
    Klinicheskaia khirurgiia, 1994, Issue:7

    Topics: Adult; Aged; Amputation, Surgical; Anti-Bacterial Agents; Arterial Occlusive Diseases; Ascorbic Acid

1994
Physiological assessment of augmented vascularity induced by VEGF in ischemic rabbit hindlimb.
    The American journal of physiology, 1994, Volume: 267, Issue:4 Pt 2

    Topics: Animals; Coronary Angiography; Dose-Response Relationship, Drug; Endothelial Growth Factors; Femoral

1994
Inferior mesenteric artery back pressure and collateral circulation to the distal colon.
    Cardiovascular surgery (London, England), 1993, Volume: 1, Issue:5

    Topics: Adult; Blood Pressure; Collateral Circulation; Colon; Colon, Sigmoid; Female; Humans; Ischemia; Male

1993
The use of photoplethysmography and Doppler ultrasound to predict anastomotic viability after segmental intestinal ischaemia in dogs.
    The European journal of surgery = Acta chirurgica, 1993, Volume: 159, Issue:1

    Topics: Anastomosis, Surgical; Animals; Arteries; Dogs; Ileum; Injections, Intra-Arterial; Ischemia; Jejunum

1993
Gastric motility and ischemic changes in occurrence of linear ulcer formation induced by restraint-water immersion stress in rat.
    Gastroenterologia Japonica, 1993, Volume: 28, Issue:3

    Topics: Animals; Gastric Mucosa; Gastrointestinal Motility; Immersion; Ischemia; Male; Microscopy, Electron,

1993
Adjunctive vasodilator therapy in the treatment of murine ischemia.
    American journal of surgery, 1993, Volume: 165, Issue:6

    Topics: Animals; Aorta, Abdominal; Captopril; Drug Therapy, Combination; Infusions, Intravenous; Ischemia; M

1993
Mesenteric ischemia after a cardiac operation: conservative treatment with local vasodilation.
    The Annals of thoracic surgery, 1996, Volume: 61, Issue:6

    Topics: Adult; Algorithms; Aortic Valve; Cardiopulmonary Bypass; Heart Valve Prosthesis; Humans; Intestines;

1996
Drug-induced vasodilation in an in vitro and in vivo study: the effects of nicardipine, papaverine, and lidocaine on the rabbit carotid artery.
    Plastic and reconstructive surgery, 1997, Volume: 100, Issue:6

    Topics: Administration, Topical; Anastomosis, Surgical; Animals; Blood Pressure; Carotid Arteries; Dose-Resp

1997
The efficient expression of intravascularly delivered DNA in rat muscle.
    Gene therapy, 1998, Volume: 5, Issue:2

    Topics: Animals; Collagenases; DNA; Gene Expression; Gene Transfer Techniques; Genetic Therapy; Injections,

1998
Acute muscle damage in latissimus dorsi grafts mobilized for cardiac assist: is vasospasm an important factor?
    Journal of cardiac surgery, 1998, Volume: 13, Issue:1

    Topics: Administration, Topical; Animals; Cardiomyoplasty; Hydralazine; Image Processing, Computer-Assisted;

1998
Spinal cord protection by papaverine and intrathecal cooling during aortic crossclamping.
    The Journal of cardiovascular surgery, 1998, Volume: 39, Issue:6

    Topics: Administration, Topical; Animals; Aorta, Thoracic; Cold Temperature; Disease Models, Animal; Intubat

1998
Limb-threatening lower extremity ischemia successfully treated with intra-arterial infusion--case reports.
    Angiology, 1999, Volume: 50, Issue:3

    Topics: Adult; Caffeine; Central Nervous System Stimulants; Drug Combinations; Ergotamine; Female; Follow-Up

1999
Mesenteric ischemia after coronary artery bypass grafting: should local continuous intra-arterial perfusion with papaverine be regarded as a treatment?
    European journal of cardio-thoracic surgery : official journal of the European Association for Cardio-thoracic Surgery, 1999, Volume: 15, Issue:2

    Topics: Acute Disease; Aged; Angina, Unstable; Coronary Artery Bypass; Follow-Up Studies; Humans; Infusions,

1999
An approach to spinal cord protection during descending or thoracoabdominal aortic repairs.
    The Annals of thoracic surgery, 1999, Volume: 67, Issue:6

    Topics: Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Drainage; Humans; Hypothermia, Induced; Ische

1999
Acute arterial spasm in an extremity caused by inadvertent intra-arterial injection successfully treated in the emergency department.
    The Journal of emergency medicine, 2000, Volume: 19, Issue:2

    Topics: Adult; Alcohol Withdrawal Delirium; Angiography; Anti-Anxiety Agents; Arm; Brachial Artery; Chlordia

2000
Ischaemia triggered by spreading neuronal activation is inhibited by vasodilators in rats.
    The Journal of physiology, 2001, Mar-01, Volume: 531, Issue:Pt 2

    Topics: Animals; Brain; Cortical Spreading Depression; Drug Combinations; Electrophysiology; Enzyme Inhibito

2001
Acute bowel ischemia after coronary bypass surgery--a catastrophic event.
    Singapore medical journal, 2001, Volume: 42, Issue:1

    Topics: Aged; Angiography; Coronary Artery Bypass; Female; Humans; Intestines; Ischemia; Laparotomy; Male; P

2001
Mesenteric ischemia after a cardiac operation: arteriosclerotic versus vasospastic etiology.
    The Journal of cardiovascular surgery, 2002, Volume: 43, Issue:1

    Topics: Adult; Aged; Cardiopulmonary Bypass; Catheterization; Coronary Artery Disease; Coronary Vasospasm; F

2002
[Prolonged intra-arterial therapy in surgical treatment of patients with critical lower limb ischemia].
    Khirurgiia, 2001, Issue:12

    Topics: Actihaemyl; Adult; Aged; Aged, 80 and over; Amputation, Surgical; Anticoagulants; Critical Care; Dip

2001
Treatment of acute central-retinal-artery occlusion.
    Lancet (London, England), 1978, Nov-25, Volume: 2, Issue:8100

    Topics: Acute Disease; Fibrinolytic Agents; Heparin; Humans; Injections, Intra-Arterial; Ischemia; Orbit; Pa

1978
Angiographic aspects of experimental nonocclusive intestinal ischemic injury.
    AJR. American journal of roentgenology, 1977, Volume: 128, Issue:6

    Topics: Angiography; Animals; Disease Models, Animal; Dogs; Humans; Infusions, Parenteral; Intestines; Ische

1977
Papaverine effect on postischemic acute renal failure in rats.
    Biomedicine / [publiee pour l'A.A.I.C.I.G.], 1977, Volume: 27, Issue:8

    Topics: Acute Kidney Injury; Animals; Creatinine; Diuresis; Female; Ischemia; Kidney; Papaverine; Potassium;

1977
Experimental studies on the action of metabolic and vasoactive substances in the brain.
    Triangle; the Sandoz journal of medical science, 1975, Volume: 14, Issue:2

    Topics: Animals; Brain; Cats; Cerebrovascular Circulation; Dihydroergotoxine; Electroencephalography; Ergolo

1975
[Effect of coronary vasodilator agents on the increase of coronary resistance during ischemia].
    Langenbecks Archiv fur Chirurgie, 1975, Volume: Suppl

    Topics: Animals; Cats; Coronary Circulation; Coronary Disease; Heart Arrest; Ischemia; Nitroglycerin; Papave

1975
Coronary reperfusion: effects of vasodilators (papaverine and adenosine).
    American heart journal, 1977, Volume: 93, Issue:1

    Topics: Adenosine; Animals; Coronary Circulation; Coronary Vessels; Disease Models, Animal; Dogs; Injections

1977
. . . . renal failure.
    Revista espanola de fisiologia, 1977, Volume: 33, Issue:2

    Topics: Acute Kidney Injury; Animals; Blood Pressure; Diuresis; Glomerular Filtration Rate; Ischemia; Kidney

1977
Initial results from an agressive roentgenological and surgical approach to acute mesenteric ischemia.
    Surgery, 1977, Volume: 82, Issue:6

    Topics: Acute Disease; Aged; Anti-Bacterial Agents; Dextrans; Humans; Ischemia; Mesenteric Arteries; Middle

1977
Vasodilatory drugs in the management of nonocclusive bowel ischemia.
    Gastroenterology, 1975, Volume: 68, Issue:1

    Topics: Aged; Female; Humans; Injections, Intra-Arterial; Intestines; Ischemia; Mesenteric Arteries; Mesente

1975
An isolated guinea pig heart preparation with in vivo like features.
    Pflugers Archiv : European journal of physiology, 1975, Volume: 353, Issue:4

    Topics: Adenine Nucleotides; Adenosine; Animals; Blood Flow Velocity; Blood Pressure; Coronary Vessels; Fema

1975
Vascular resistance in hypothermically perfused kidneys damaged by warm ischemia.
    Scandinavian journal of urology and nephrology, 1976, Volume: 10, Issue:1

    Topics: Animals; Arterial Occlusive Diseases; Dextrans; Extracorporeal Circulation; Ischemia; Kidney; Papave

1976
The influence of an agonal phase on the vascular resistance of the kidney measured during hypothermic perfusion studies.
    Scandinavian journal of urology and nephrology, 1976, Volume: 10, Issue:1

    Topics: Animals; Death; Dextrans; Ischemia; Kidney; Papaverine; Perfusion; Rabbits; Temperature; Time Factor

1976
Praxilene (naftidrofuryl oxalate) as an alternative for the augmentation of femoro-distal bypass blood flow.
    European journal of vascular surgery, 1992, Volume: 6, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Blood Flow Velocity; Femoral Artery; Humans; Ischemia; Leg; Middle A

1992
Naftidrofluryl dose and vascular resistance.
    European journal of vascular surgery, 1992, Volume: 6, Issue:6

    Topics: Dose-Response Relationship, Drug; Femoral Artery; Humans; Injections, Intra-Arterial; Ischemia; Leg;

1992
Outflow resistance measurements.
    Annales chirurgiae et gynaecologiae, 1992, Volume: 81, Issue:2

    Topics: Angiography; Blood Flow Velocity; Graft Occlusion, Vascular; Humans; Ischemia; Leg; Papaverine; Ultr

1992
The interaction of vasodilating drugs and sympathetic blockade in normal and ischemic canine hindlimbs.
    Journal of vascular surgery, 1991, Volume: 13, Issue:6

    Topics: Anesthesia, Epidural; Animals; Autonomic Nerve Block; Blood Pressure; Dogs; Female; Hindlimb; Infusi

1991
The "isolated" popliteal segment: a comparative evaluation of its vascular resistance.
    European journal of vascular surgery, 1990, Volume: 4, Issue:5

    Topics: Femoral Artery; Humans; Ischemia; Leg; Papaverine; Popliteal Artery; Radiography; Regional Blood Flo

1990
St. Anthony's fire: successful reversal of ergotamine-induced peripheral vasospasm by hydrostatic dilatation.
    Annals of vascular surgery, 1990, Volume: 4, Issue:6

    Topics: Catheterization; Dihydroergotamine; Drug Combinations; Ergotism; Gangrene; Heparin; Heparin, Low-Mol

1990
Appraisal of cerebrospinal fluid alterations during aortic surgery with intrathecal papaverine administration and cerebrospinal fluid drainage.
    Journal of vascular surgery, 1990, Volume: 11, Issue:3

    Topics: Aorta; Cerebrospinal Fluid; Cerebrospinal Fluid Pressure; Drainage; Female; Humans; Injections, Spin

1990
Nonocclusive mesenteric ischemia in renal patients: recognition and prevention of intestinal gangrene.
    American journal of kidney diseases : the official journal of the National Kidney Foundation, 1990, Volume: 15, Issue:6

    Topics: Aged; Humans; Infarction; Intestines; Ischemia; Kidney Failure, Chronic; Male; Mesenteric Arteries;

1990
A simple "solution" worth consideration to combat limb ischemia induced by intraaortic balloon pumping.
    The Journal of thoracic and cardiovascular surgery, 1989, Volume: 98, Issue:2

    Topics: Female; Humans; Intra-Aortic Balloon Pumping; Ischemia; Leg; Male; Papaverine

1989
[Reactive vasospasm in the newborn treated by papaverine infusion].
    Harefuah, 1987, May-01, Volume: 112, Issue:9

    Topics: Catheterization; Humans; Infant, Low Birth Weight; Infant, Newborn; Infusions, Intra-Arterial; Ische

1987
Selective mesenteric vasodilators. A future role in acute mesenteric ischemia?
    Gastroenterology, 1986, Volume: 91, Issue:1

    Topics: Acute Disease; Humans; Ischemia; Mesenteric Arteries; Papaverine; Urotensins; Vasodilator Agents

1986
Comparison of an intravenous selective mesenteric vasodilator with intraarterial papaverine in experimental nonocclusive mesenteric ischemia.
    Gastroenterology, 1986, Volume: 91, Issue:1

    Topics: Animals; Blood Pressure; Dogs; Female; Infusions, Intra-Arterial; Infusions, Parenteral; Ischemia; M

1986
Collateral blood flow in segmental intestinal ischemia: effects of vasoactive agents.
    Surgery, 1986, Volume: 100, Issue:2

    Topics: Animals; Blood Pressure; Collateral Circulation; Dogs; Female; Ischemia; Isoproterenol; Jejunum; Mal

1986
The use of topical vasodilators as an adjunct in infant renal surgery.
    The Journal of urology, 1985, Volume: 134, Issue:2

    Topics: Administration, Topical; Female; Humans; Infant; Infant, Newborn; Intraoperative Care; Intraoperativ

1985
[Proceedings: Microcirculation and ventricular-wall function in the normal and partially ischemia-damaged myocardium under pharmacologic influence in animal experiment].
    Zeitschrift fur Kardiologie, 1974, Volume: 0, Issue:Suppl 1

    Topics: Adrenergic beta-Antagonists; Animals; Coronary Vessels; Digoxin; Dipyridamole; Dogs; Heart; Ischemia

1974
Coronary artery bypass graft haemodynamics.
    British heart journal, 1973, Volume: 35, Issue:5

    Topics: Coronary Artery Bypass; Coronary Circulation; Humans; Ischemia; Nitroglycerin; Papaverine

1973
[Drug therapy of acute cerebral ischemia. Clinical study].
    Giornale di clinica medica, 1974, Volume: 55, Issue:12

    Topics: Brain; Dextrans; Dihydroergotoxine; Ergoloid Mesylates; Humans; Intracranial Arteriosclerosis; Intra

1974
Pathogenesis of redistribution of intrarenal blood flow in haemorrhagic hypotension.
    European journal of clinical investigation, 1971, Volume: 1, Issue:4

    Topics: Acetylcholine; Angiotensin II; Animals; Autoradiography; Blood Flow Velocity; Dogs; Hypotension; Isc

1971
Hyperbaric oxygenation as a therapeutic method in experimental subacute and chronic peripheral circulatory disturbances.
    Acta chirurgica Academiae Scientiarum Hungaricae, 1969, Volume: 10, Issue:4

    Topics: Animals; Disease Models, Animal; Ergotamine; Ethanolamines; Gangrene; Hyperbaric Oxygenation; Ischem

1969
Peripheral ischemia secondary to ergotamine intoxication.
    Archives of surgery (Chicago, Ill. : 1960), 1974, Volume: 109, Issue:6

    Topics: Adult; Angiography; Ergotamine; Foot; Foot Diseases; Gangrene; Humans; Ischemia; Leg; Male; Migraine

1974
Preliminary report. Hypothermic renal storage. I. Adverse effect of papaverine.
    The Journal of surgical research, 1973, Volume: 15, Issue:3

    Topics: Animals; Cold Temperature; Creatinine; Dogs; Female; Ischemia; Kidney; Kidney Transplantation; Papav

1973
[Drug-induced reaction patterns of regional cerebral blood flow (author's transl)].
    Deutsche medizinische Wochenschrift (1946), 1974, Volume: 99, Issue:8

    Topics: Administration, Oral; Benzamides; Benzoates; Blood Pressure; Brain; Cerebrovascular Circulation; Cer

1974
In situ vein bypass. Experiences with new vein valve strippers.
    Scandinavian journal of thoracic and cardiovascular surgery, 1973, Volume: 7, Issue:1

    Topics: Adult; Aged; Ampicillin; Anticoagulants; Arteriovenous Shunt, Surgical; Dextrans; Female; Femoral Ve

1973
Renin release from the ischaemic kidney.
    British journal of pharmacology, 1973, Volume: 48, Issue:1

    Topics: Animals; Blood Pressure; Cisterna Magna; Ischemia; Kidney; Ligation; Male; Neurons; Papaverine; Perf

1973
Angiographic diagnosis of mesenteric arterial vasoconstriction.
    Radiology, 1974, Volume: 112, Issue:3

    Topics: Aged; Angiography; Animals; Constriction; Dogs; Female; Humans; Ischemia; Male; Mesenteric Arteries;

1974
An evaluation of pedicle infiltration, organ perfusion, and prevention of vascular collapse during canine kidney procurement for transplantation.
    The Journal of surgical research, 1968, Volume: 8, Issue:7

    Topics: Acetylcholine; Acute Kidney Injury; Animals; Dogs; Injections, Intra-Arterial; Ischemia; Isotonic So

1968
Vascular resistance in hypothermically perfused kidneys following one hour of warm ischaemia.
    Acta medica Scandinavica, 1972, Volume: 191, Issue:5

    Topics: Animals; Blood Pressure; Heparin; Hot Temperature; Hypothermia, Induced; Ischemia; Kidney; Papaverin

1972
Effect of perfusion pressure and hematocrit on capillary flow and transport in hyperemic skeletal muscle of the dog.
    Microvascular research, 1972, Volume: 4, Issue:3

    Topics: Animals; Biological Transport; Capillary Permeability; Diffusion; Dogs; Female; Hematocrit; Iodides;

1972
Operative blood flow in femoral-popliteal and femoral-tibial grafts for lower extremity ischemia.
    Archives of surgery (Chicago, Ill. : 1960), 1971, Volume: 103, Issue:5

    Topics: Angiography; Arteries; Blood Flow Velocity; Blood Pressure Determination; Blood Vessel Prosthesis; D

1971
[Therapy of lower extremity ischemic disease in ambulatory field practice using infusions].
    Casopis lekaru ceskych, 1970, Jul-28, Volume: 109, Issue:36

    Topics: Aged; Ambulatory Care; Arteriosclerosis Obliterans; Humans; Infusions, Parenteral; Ischemia; Leg; Pa

1970
Muscle blood flow and 86Rb extraction: 86Rb as a capillary flow indicator.
    The American journal of physiology, 1968, Volume: 214, Issue:3

    Topics: Animals; Capillaries; Capillary Permeability; Dogs; Ischemia; Muscles; Papaverine; Perfusion; Radioi

1968
Salvage of the ischemic limb. Hemodynamic changes during surgery.
    JAMA, 1968, Apr-15, Volume: 204, Issue:3

    Topics: Adult; Aged; Amputation, Surgical; Aorta, Abdominal; Blood Flow Velocity; Blood Pressure; Blood Vess

1968
[Medical treatment of acute arterial obliteration in the limbs].
    Revue de l'atherosclerose et des arteriopathies peripheriques, 1968, Volume: 10, Issue:2

    Topics: Acute Disease; Adult; Aged; Arteriosclerosis Obliterans; Drug Synergism; Female; Fibrinolytic Agents

1968
Sustained release papaverine in peripheral ischemia: report of 21 ambulatory cases with oscillometric studies.
    Southern medical journal, 1969, Volume: 62, Issue:7

    Topics: Adult; Aged; Arteriosclerosis; Delayed-Action Preparations; Female; Humans; Intermittent Claudicatio

1969