papaverine has been researched along with Intracranial Hypertension in 3 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Intracranial Hypertension: Increased pressure within the cranial vault. This may result from several conditions, including HYDROCEPHALUS; BRAIN EDEMA; intracranial masses; severe systemic HYPERTENSION; PSEUDOTUMOR CEREBRI; and other disorders.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intra-arterial papaverine (IAP) is used to treat symptomatic cerebral vasospasm following aneurysmal subarachnoid hemorrhage (SAH)." | 3.73 | Intra-arterial papaverine used to treat cerebral vasospasm reduces brain oxygen. ( Hurst, RW; LeRoux, PD; Maloney-Wilensky, E; Spiotta, AM; Stiefel, MF; Udoetuk, JD; Weigele, JB, 2006) |
| "Intraarterial papaverine infusions are performed to reverse cerebral arterial vasospasm resulting from subarachnoid hemorrhage, but such infusions may lead to increases in intracranial pressure (ICP)." | 3.70 | Intracranial pressure monitoring during intraarterial papaverine infusion for cerebral vasospasm. ( Angtuaco, EE; Cross, DT; Dacey, RG; Diringer, MN; Milburn, JM; Moran, CJ, 1998) |
| "Two patients showed signs of elevated intracranial pressure after the procedures and also had ASrO2 readings exceeding 15%; measures to lower arterial hypertension reduced SrO2 in these patients." | 2.72 | [Behaviour of near-infrared cerebral oximetry readings during percutaneous carotid angioplasty]. ( Carrero, E; Fàbregas, N; Fontanals, J; Rodríguez, L; Salvador, L; Valero, R, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 2 (66.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Stiefel, MF | 1 |
| Spiotta, AM | 1 |
| Udoetuk, JD | 1 |
| Maloney-Wilensky, E | 1 |
| Weigele, JB | 1 |
| Hurst, RW | 1 |
| LeRoux, PD | 1 |
| Rodríguez, L | 1 |
| Salvador, L | 1 |
| Valero, R | 1 |
| Carrero, E | 1 |
| Fontanals, J | 1 |
| Fàbregas, N | 1 |
| Cross, DT | 1 |
| Moran, CJ | 1 |
| Angtuaco, EE | 1 |
| Milburn, JM | 1 |
| Diringer, MN | 1 |
| Dacey, RG | 1 |
1 trial available for papaverine and Intracranial Hypertension
| Article | Year |
|---|---|
[Behaviour of near-infrared cerebral oximetry readings during percutaneous carotid angioplasty].
Topics: Aged; Angioplasty, Balloon; Blood Pressure; Brain Ischemia; Carotid Artery, Internal; Carotid Stenos | 2006 |
2 other studies available for papaverine and Intracranial Hypertension
| Article | Year |
|---|---|
Intra-arterial papaverine used to treat cerebral vasospasm reduces brain oxygen.
Topics: Blood Pressure; Body Temperature; Brain; Cerebral Angiography; Humans; Injections, Intra-Arterial; I | 2006 |
Intracranial pressure monitoring during intraarterial papaverine infusion for cerebral vasospasm.
Topics: Age Factors; Drug Administration Schedule; Glasgow Coma Scale; Humans; Infusion Pumps; Infusions, In | 1998 |