papaverine has been researched along with Intracranial Arteriosclerosis in 28 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Intracranial Arteriosclerosis: Vascular diseases characterized by thickening and hardening of the walls of ARTERIES inside the SKULL. There are three subtypes: (1) atherosclerosis with fatty deposits in the ARTERIAL INTIMA; (2) Monckeberg's sclerosis with calcium deposits in the media and (3) arteriolosclerosis involving the small caliber arteries. Clinical signs include HEADACHE; CONFUSION; transient blindness (AMAUROSIS FUGAX); speech impairment; and HEMIPARESIS.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 27 (96.43) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (3.57) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Miyazaki, M | 1 |
| Shkrobom, SI | 1 |
| Komorovskaia, IaM | 1 |
| Nechaĭ, EE | 1 |
| Patrignani, S | 1 |
| Graziani, A | 1 |
| Ranieri, A | 1 |
| Russo, O | 1 |
| Didion, SP | 1 |
| Heistad, DD | 1 |
| Faraci, FM | 1 |
| Man'kovskiĭ, NB | 1 |
| Mints, AIa | 1 |
| Lizogub, VG | 1 |
| Kim, B | 1 |
| Cacciatori, D | 1 |
| Duvoisin, RC | 1 |
| Hünermann, VB | 1 |
| Felix, R | 1 |
| Wesener, K | 1 |
| Winkler, C | 1 |
| Almici, C | 1 |
| Lazzaroni, G | 1 |
| Zdichynec, B | 1 |
| Klaus, P | 1 |
| Wiethaup, H | 1 |
| Bambasová, E | 1 |
| Bílková, J | 1 |
| Budínská, K | 1 |
| Hadjiev, D | 1 |
| Bazo, AJ | 1 |
| Furuta, K | 1 |
| Probst, G | 1 |
| Keiser, G | 1 |
| Stern, FH | 1 |
| Yoshida, S | 1 |
| Fujimoto, J | 1 |
| Tone, K | 1 |
| Sawami, K | 1 |
| LaBrecque, DC | 1 |
| Mamo, H | 1 |
| Seylaz, J | 1 |
| Rey, A | 1 |
| Houdart, R | 1 |
| Mori, A | 1 |
| Ishikawa, Y | 1 |
| Mukoyama, K | 1 |
| Bianchi, G | 1 |
| Vidovszky, T | 1 |
| Blanc, A | 1 |
| Perset, P | 1 |
| Simard, D | 1 |
| Olesen, J | 1 |
| Paulson, OB | 1 |
| Lassen, NA | 1 |
| Skinhoj, E | 1 |
| Klinkerfuss, GH | 1 |
| Capitanucci, P | 1 |
| Martinelli, M | 1 |
| De Gregorio, M | 1 |
1 review available for papaverine and Intracranial Arteriosclerosis
| Article | Year |
|---|---|
Impedance methods for investigation of cerebral circulation.
Topics: Adenosine Triphosphate; Animals; Brain Neoplasms; Carbon Dioxide; Carotid Artery Diseases; Cerebral | 1972 |
5 trials available for papaverine and Intracranial Arteriosclerosis
| Article | Year |
|---|---|
[Results of Paveron 75 therapy in negatively selected patients with cerebral function disorders].
Topics: Ascorbic Acid; Clinical Trials as Topic; Drug Therapy, Combination; Humans; Intracranial Arterioscle | 1973 |
Papaverin in the treatment of geriatric patients.
Topics: Aged; Clinical Trials as Topic; Drug Evaluation; Ethanol; Female; Humans; Intracranial Arteriosclero | 1974 |
An ergot alkaloid preparation (Hydergine) versus papaverine in treating common complaints of the aged: double-blind study.
Topics: Aged; Behavior; Cerebrovascular Disorders; Clinical Trials as Topic; Cognition Disorders; Emotions; | 1973 |
[Clinical study of a new vasodilating agent (Dilydrin) in cerebral vascular disorders and strokes].
Topics: Aged; Catecholamines; Cerebrovascular Disorders; Clinical Trials as Topic; Female; Humans; Intracran | 1969 |
Management of chronic brain syndrome secondary to cerebral arteriosclerosis, with special reference to papaverine hydrochloride.
Topics: Aged; Anxiety; Clinical Trials as Topic; Dementia; Depression; Humans; Intracranial Arteriosclerosis | 1970 |
22 other studies available for papaverine and Intracranial Arteriosclerosis
| Article | Year |
|---|---|
Measurement of cerebral blood flow by ultasonic Doppler technique. Hemodynamic correlation of internal carotid artery and vertebral artery.
Topics: Adult; Aged; Aging; Blood Flow Velocity; Carotid Arteries; Cerebral Hemorrhage; Cerebrovascular Circ | 1966 |
[Changes in the systemic hemodynamics of patients with chronic cerebrovascular insufficiency].
Topics: Adult; Aged; Aminophylline; Cerebrovascular Circulation; Cerebrovascular Disorders; Dextrans; Drug T | 1980 |
[Effect of papaverine on systemic and cerebral hemodynamics in atherosclerosis complicated by chronic cerebral circulatory insufficiency].
Topics: Aged; Blood Circulation Time; Blood Pressure; Cerebrovascular Disorders; Female; Humans; Hypertensio | 1984 |
[Experience with the use of papaverolina in patients with arterial diseases].
Topics: Aged; Arterial Occlusive Diseases; Arteriosclerosis Obliterans; Blood Flow Velocity; Electrocardiogr | 1981 |
Mechanisms that produce nitric oxide-mediated relaxation of cerebral arteries during atherosclerosis.
Topics: Animals; Basilar Artery; Cerebral Arteries; Cholesterol; Diet, Atherogenic; Dinoprost; Disease Model | 2001 |
[Regional cerebral blood flow and its regulation in the initial stage of cerebral arteriosclerosis].
Topics: Adrenergic alpha-Antagonists; Adult; Blood Flow Velocity; Cerebrovascular Circulation; Female; Hemod | 1979 |
[Experience with the combination of vincamine and papaverine in chronic brain syndrome].
Topics: Aged; Brain Ischemia; Cerebrovascular Disorders; Chronic Disease; Drug Therapy, Combination; Female; | 1979 |
Antagonism of levodopa by papaverine.
Topics: Aged; Corpus Striatum; Fatigue; Female; Headache; Humans; Hyperhidrosis; Intracranial Arterioscleros | 1975 |
[Effect of papaverine hydrochloride on brain circulation. Studies using a scintillation camera computer system].
Topics: Cerebrovascular Circulation; Computers; Female; Humans; Intracranial Arteriosclerosis; Male; Mathema | 1975 |
[Drug therapy of acute cerebral ischemia. Clinical study].
Topics: Brain; Dextrans; Dihydroergotoxine; Ergoloid Mesylates; Humans; Intracranial Arteriosclerosis; Intra | 1974 |
[Diagnostic and therapeutic difficulties in cerebral atherosclerosis (author's transl)].
Topics: Anabolic Agents; Humans; Intracranial Arteriosclerosis; Papaverine; Reserpine | 1974 |
[Clinical-pathological investigation on retinal and cerebral hemodynamics].
Topics: Adolescent; Adult; Age Factors; Aged; Amino Alcohols; Benzoates; Blood Pressure; Blood Volume; Cereb | 1972 |
[Comparative study of Xe133 washout method and ultrasonic blood rheography].
Topics: Adult; Aged; Carbon Dioxide; Cerebrovascular Circulation; Cerebrovascular Disorders; Female; Humans; | 1970 |
Papaverine hydrochloride as therapy for mentally confused geriatric patients.
Topics: Aged; Humans; Intracranial Arteriosclerosis; Male; Mental Disorders; Middle Aged; Papaverine | 1966 |
[Pharmacodynamic study of blood flow in the human cerebral cortex by a continuous and focal measurement method].
Topics: Blood Flow Velocity; Body Temperature; Carbon Dioxide; Cerebral Cortex; Cerebrovascular Circulation; | 1970 |
Study of the effect of N-methyl carbamate on the electroencephalogram in cerebral arteriosclerosis.
Topics: Aged; Carbamates; Electroencephalography; Humans; Hydralazine; Intracranial Arteriosclerosis; Middle | 1967 |
[The use of high doses of papaverine in cerebral arteriosclerotic vascular disease].
Topics: Encephalomalacia; Humans; Intracranial Arteriosclerosis; Papaverine; Paralysis | 1970 |
[Comparative study on the vasodilatory activities of bencyclane and papaverine by cerebral angiography].
Topics: Adult; Aged; Brain Neoplasms; Cerebral Angiography; Cycloheptanes; Diagnosis, Differential; Female; | 1970 |
[Use of theophyllinyl 7- -n propane sulfonate of papaverine in rehabilitation and functional readaptation].
Topics: Aged; Arteritis; Cerebrovascular Disorders; Female; Hemiplegia; Humans; Intracranial Arteriosclerosi | 1971 |
Regional cerebral blood flow and its regulation in dementia.
Topics: Adult; Aged; Alcohol Amnestic Disorder; Biopsy; Blood Flow Velocity; Brain; Carbon Dioxide; Cerebral | 1971 |
Cerebral ischemia.
Topics: Adult; Aged; Anticoagulants; Auscultation; Cerebral Angiography; Cerebrovascular Disorders; Diagnosi | 1967 |
[Rheographic study of the activity of some vasoactive drugs on peripheral arterial circulation].
Topics: Adult; Aged; Antihypertensive Agents; Arteriosclerosis Obliterans; Blood Circulation; Cerebrovascula | 1968 |