papaverine has been researched along with Intracranial Aneurysm in 62 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Intracranial Aneurysm: Abnormal outpouching in the wall of intracranial blood vessels. Most common are the saccular (berry) aneurysms located at branch points in CIRCLE OF WILLIS at the base of the brain. Vessel rupture results in SUBARACHNOID HEMORRHAGE or INTRACRANIAL HEMORRHAGES. Giant aneurysms (
| Excerpt | Relevance | Reference |
|---|---|---|
| "Intra-arterial infusion of papaverine was used clinically as a vasodilator for spastic arteries after subarachnoid hemorrhage, since in vitro experiment demonstrated that papaverine is one of the most potent vasodilators of human cerebral arteries following subarachnoid hemorrhage." | 9.07 | Intra-arterial papaverine for the treatment of cerebral vasospasm after subarachnoid hemorrhage. ( Hashimoto, N; Kazekawa, K; Tsukahara, T; Yoshimura, S, 1994) |
| "The clinical efficacy of percutaneous transluminal angioplasty and intra-arterial papaverine infusion for treatment of vasospasm following subarachnoid hemorrhage was investigated." | 7.70 | Clinical evaluation of the effect of percutaneous transluminal angioplasty and intra-arterial papaverine infusion for the treatment of vasospasm following aneurysmal subarachnoid hemorrhage. ( Ishihara, S; Kaji, T; Katoh, H; Makita, K; Miyazawa, T; Nawashiro, H; Shima, K; Shimizu, A; Takiguchi, H; Tsuchiya, K; Umezawa, H, 1999) |
| "The purpose of this study was to test the hypothesis that balloon angioplasty is superior to papaverine infusion for the treatment of proximal anterior circulation arterial vasospasm following subarachnoid hemorrhage (SAH)." | 7.70 | Comparison of balloon angioplasty and papaverine infusion for the treatment of vasospasm following aneurysmal subarachnoid hemorrhage. ( Douville, CM; Elliott, JP; Eskridge, JM; Grady, MS; Lam, DJ; Le Roux, PD; Lewis, DH; Mayberg, MR; Newell, DW; Winn, HR, 1998) |
| "We describe two patients who had cerebral vasospasm after subarachnoid hemorrhage that was refractory to intraarterial injection of papaverine." | 7.69 | Intraarterial injection of amrinone for vasospasm induced by subarachnoid hemorrhage. ( Nakamura, S; Watanabe, H; Yoshida, K, 1997) |
| "To evaluate the techniques and efficacy of intracranial intraarterial papaverine infusion for symptomatic vasospasm after subarachnoid hemorrhage caused by aneurysm rupture." | 7.69 | Intraarterial papaverine infusion for cerebral vasospasm after subarachnoid hemorrhage. ( Aldrich, EF; Clouston, JE; Numaguchi, Y; Simard, JM; Zitnay, KM; Zoarski, GH, 1995) |
| "This report describes the successful treatment of cerebral vasospasm after subarachnoid hemorrhage with superselective intra-arterial infusion of papaverine hydrochloride." | 7.68 | Superselective intra-arterial infusion of papaverine for the treatment of cerebral vasospasm after subarachnoid hemorrhage. ( Kaku, Y; Kazekawa, K; Tsukahara, T; Yonekawa, Y, 1992) |
| "The case of a patient with an anterior communicating artery aneurysm, who received intracisternal papaverine by instillation after aneurysm clipping, is reported." | 6.47 | Association of acute onset hypertension and tachycardia following intracisternal papaverine administration during intracranial aneurysm surgery: a case report and review of the literature. ( Agrawal, S; Sahu, S; Srivastava, VK, 2011) |
| "Cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage is still a leading cause of morbidity and death." | 5.36 | Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report. ( Aytunur, CS; Baltaci, B; Basar, H; Gulhan, Y; Ozcan, A, 2010) |
| "Here, we describe a case of anterior communicating artery aneurysm with hydrocephalus." | 5.33 | Haemodynamic changes after intracisternal papaverine instillation during intracranial aneurysmal surgery. ( Dash, HH; Prabhakar, H; Rath, GP; Suri, A, 2006) |
| "Papaverine was infused into 32 arteries on 23 occasions." | 5.30 | Intra-arterial papaverine for the treatment of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. ( Firlik, AD; Firlik, KS; Jungreis, CA; Kaufmann, AM; Yonas, H, 1999) |
| "The ruptured anterior communicating artery aneurysm was surgically obliterated the following day, and thereafter maximum hypervolemic and hypertensive therapies were used." | 5.29 | Paradoxical aggravation of vasospasm with papaverine infusion following aneurysmal subarachnoid hemorrhage. Case report. ( Clyde, BL; Firlik, AD; Kaufmann, AM; Spearman, MP; Yonas, H, 1996) |
| "Intra-arterial infusion of papaverine was used clinically as a vasodilator for spastic arteries after subarachnoid hemorrhage, since in vitro experiment demonstrated that papaverine is one of the most potent vasodilators of human cerebral arteries following subarachnoid hemorrhage." | 5.07 | Intra-arterial papaverine for the treatment of cerebral vasospasm after subarachnoid hemorrhage. ( Hashimoto, N; Kazekawa, K; Tsukahara, T; Yoshimura, S, 1994) |
| "In 43 cases with symptomatic cerebral vasospasm after aneurysmal subarachnoid hemorrhage treated by intraarterial infusion of papaverine (IAP), we studied cerebral hemodynamics by measuring cerebral circulation time (CCT) using digital subtraction angiogram." | 3.71 | Intraarterial infusion of papaverine and change of cerebral hemodynamics in symptomatic cerebral vasospasm. ( Kuwamura, K; Minami, H; Tamaki, N, 2001) |
| "The purpose of this study was to test the hypothesis that balloon angioplasty is superior to papaverine infusion for the treatment of proximal anterior circulation arterial vasospasm following subarachnoid hemorrhage (SAH)." | 3.70 | Comparison of balloon angioplasty and papaverine infusion for the treatment of vasospasm following aneurysmal subarachnoid hemorrhage. ( Douville, CM; Elliott, JP; Eskridge, JM; Grady, MS; Lam, DJ; Le Roux, PD; Lewis, DH; Mayberg, MR; Newell, DW; Winn, HR, 1998) |
| "Improvement in cerebral oxygenation as well as prevention of cerebral lactic acidosis can be successfully achieved after intraarterial infusion of papaverine." | 3.70 | Improvement of cerebral oxygenation patterns and metabolic validation of superselective intraarterial infusion of papaverine for the treatment of cerebral vasospasm. ( Fandino, J; Kaku, Y; Schuknecht, B; Valavanis, A; Yonekawa, Y, 1998) |
| "The clinical efficacy of percutaneous transluminal angioplasty and intra-arterial papaverine infusion for treatment of vasospasm following subarachnoid hemorrhage was investigated." | 3.70 | Clinical evaluation of the effect of percutaneous transluminal angioplasty and intra-arterial papaverine infusion for the treatment of vasospasm following aneurysmal subarachnoid hemorrhage. ( Ishihara, S; Kaji, T; Katoh, H; Makita, K; Miyazawa, T; Nawashiro, H; Shima, K; Shimizu, A; Takiguchi, H; Tsuchiya, K; Umezawa, H, 1999) |
| "We describe two patients who had cerebral vasospasm after subarachnoid hemorrhage that was refractory to intraarterial injection of papaverine." | 3.69 | Intraarterial injection of amrinone for vasospasm induced by subarachnoid hemorrhage. ( Nakamura, S; Watanabe, H; Yoshida, K, 1997) |
| "To evaluate the techniques and efficacy of intracranial intraarterial papaverine infusion for symptomatic vasospasm after subarachnoid hemorrhage caused by aneurysm rupture." | 3.69 | Intraarterial papaverine infusion for cerebral vasospasm after subarachnoid hemorrhage. ( Aldrich, EF; Clouston, JE; Numaguchi, Y; Simard, JM; Zitnay, KM; Zoarski, GH, 1995) |
| "This report describes the successful treatment of cerebral vasospasm after subarachnoid hemorrhage with superselective intra-arterial infusion of papaverine hydrochloride." | 3.68 | Superselective intra-arterial infusion of papaverine for the treatment of cerebral vasospasm after subarachnoid hemorrhage. ( Kaku, Y; Kazekawa, K; Tsukahara, T; Yonekawa, Y, 1992) |
| "We examined the efficacy of slow-release, and prolonged diffusion silicone pellets mixed with papaverine hydrochloride in the treatment of cerebral vasospasms following subarachnoid hemorrhage." | 3.67 | [Sustained-release pellet of vasodilators--basic experiment]. ( Arimitsu, T; Mori, K; Oda, Y; Okumura, T, 1984) |
| "Vasospasm as a complication of subarachnoid hemorrhage is a major concern in clinical practice." | 2.70 | Efficacy of controlled-release papaverine pellets in preventing symptomatic cerebral vasospasm. ( Cagli, S; Dalbasti, T; Karabiyikoglu, M; Oktar, N; Ozdamar, N, 2001) |
| "We critically reviewed current literature on the adverse effects of iPPV in aneurysmal surgery with a focus on oculomotor nerve involvement." | 2.58 | Prolonged Intracisternal Papaverine Toxicity: Index Case Description and Proposed Mechanism of Action. ( Alambyan, V; Kohen, M; Manjila, S; Ostergard, T; Pace, J; Ramos-Estebanez, C; Zhou, X, 2018) |
| "The case of a patient with an anterior communicating artery aneurysm, who received intracisternal papaverine by instillation after aneurysm clipping, is reported." | 2.47 | Association of acute onset hypertension and tachycardia following intracisternal papaverine administration during intracranial aneurysm surgery: a case report and review of the literature. ( Agrawal, S; Sahu, S; Srivastava, VK, 2011) |
| "Treatment of acute aneurysmal subarachnoid hemorrhages consists of occluding the aneurysm to prevent rebleed, attempting to prevent vasospasm, and maintaining blood flow to the brain through vessels in vasospasm." | 2.43 | Endovascular management of a patient after SAH. ( Chang, S; Murphy, K; Srinivas, A, 2005) |
| "For survivors of aneurysmal subarachnoid hemorrhage, cerebral vasospasm significantly contributes to its morbidity and mortality by causing delayed ischemic neurological deficit." | 2.40 | Neuroradiologic diagnosis and treatment of vasospasm. ( Elliott, JP; Eskridge, JM; Song, JK, 1997) |
| "Papaverine (3%, 60 mg) was dropped into the internal carotid artery cistern to relieve vascular spasm and act on the oculomotor nerve intentionally at the same time." | 1.40 | Intra- and post-operational changes in pupils induced by local application of cisternal papaverine during cerebral aneurysm operations. ( Huang, C; Ma, C; Yan, Z; Zhou, W, 2014) |
| "Cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage is still a leading cause of morbidity and death." | 1.36 | Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report. ( Aytunur, CS; Baltaci, B; Basar, H; Gulhan, Y; Ozcan, A, 2010) |
| "Here, we describe a case of anterior communicating artery aneurysm with hydrocephalus." | 1.33 | Haemodynamic changes after intracisternal papaverine instillation during intracranial aneurysmal surgery. ( Dash, HH; Prabhakar, H; Rath, GP; Suri, A, 2006) |
| "The best strategy for treatment of subarachnoid hemorrhage due to ruptured cerebral aneurysm is obliteration of the aneurysm as soon as possible." | 1.32 | Combined endovascular treatment for both intracranial aneurysm and symptomatic vasospasm. ( Duckwiler, GR; Gobin, YP; Martin, NA; Murayama, Y; Patel, AB; Song, JK; Tateshima, S; Uda, K; Viñuela, F, 2003) |
| "Patients who developed cerebral vasospasm and underwent cerebral arteriographic, transcranial Doppler ultrasonographic, and cerebral blood flow (CBF) studies before and after endovascular therapy for cerebral arterial spasm (vasospasm) were included in this study." | 1.31 | Multimodal quantitation of the effects of endovascular therapy for vasospasm on cerebral blood flow, transcranial doppler ultrasonographic velocities, and cerebral artery diameters. ( Afari, A; Glenn, TC; Gonzalez, NR; Guthrie, D; Lee, JH; Martin, NA; Oskouian, RJ; Viñuela, F, 2002) |
| "Incidence of cerebral vasospasm on angiograms among the two groups was analysed." | 1.31 | Magnesium: a useful adjunct in the prevention of cerebral vasospasm following aneurysmal subarachnoid haemorrhage. ( Chia, RY; Hughes, RS; Morgan, MK, 2002) |
| "Ninety nine patients with ruptured cerebral aneurysms, who survived more than one week and were treated in Wakayama City in 1994, were studied." | 1.30 | The effect of endovascular therapy for cerebral arterial spasm, its limitation and pitfalls. ( Hyotani, G; Itakura, T; Kido, T; Kinoshita, Y; Kuriyama, T; Naka, Y; Nakai, K; Terada, T; Tsuura, M; Yokote, H, 1997) |
| "Papaverine was infused into 32 arteries on 23 occasions." | 1.30 | Intra-arterial papaverine for the treatment of cerebral vasospasm following aneurysmal subarachnoid hemorrhage. ( Firlik, AD; Firlik, KS; Jungreis, CA; Kaufmann, AM; Yonas, H, 1999) |
| "It is difficult to treat ruptured aneurysms with symptomatic vasospasm." | 1.30 | [Endovascular surgery for untreated ruptured aneurysm with symptomatic vasospasm]. ( Akiyama, Y; Hayashi, N; Higashi, T; Kikuchi, H; Kokuzawa, J; Manaka, H; Morizane, A; Nagata, I; Nakahara, I; Namura, S; Nishizaki, J; Sakai, H; Sakai, N; Takahashi, J; Yanamoto, H, 1999) |
| "The ruptured anterior communicating artery aneurysm was surgically obliterated the following day, and thereafter maximum hypervolemic and hypertensive therapies were used." | 1.29 | Paradoxical aggravation of vasospasm with papaverine infusion following aneurysmal subarachnoid hemorrhage. Case report. ( Clyde, BL; Firlik, AD; Kaufmann, AM; Spearman, MP; Yonas, H, 1996) |
| "The study focused on patients with aneurysmal subarachnoid hemorrhage who developed clinical signs and symptoms of vasospasm, which was documented by cerebral angiography." | 1.29 | Intracranial pressure changes induced during papaverine infusion for treatment of vasospasm. ( Eskridge, JM; Grady, MS; McAuliffe, W; Newell, DW; Townsend, M; Winn, HR, 1995) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 11 (17.74) | 18.7374 |
| 1990's | 24 (38.71) | 18.2507 |
| 2000's | 18 (29.03) | 29.6817 |
| 2010's | 9 (14.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Zhou, X | 1 |
| Alambyan, V | 1 |
| Ostergard, T | 1 |
| Pace, J | 1 |
| Kohen, M | 1 |
| Manjila, S | 1 |
| Ramos-Estebanez, C | 1 |
| Praeger, AJ | 1 |
| Lewis, PM | 1 |
| Hwang, PY | 1 |
| Zhou, W | 1 |
| Ma, C | 1 |
| Huang, C | 1 |
| Yan, Z | 1 |
| Zygourakis, CC | 1 |
| Vasudeva, V | 1 |
| Lai, PM | 1 |
| Kim, AH | 1 |
| Wang, H | 1 |
| Du, R | 1 |
| Singla, N | 1 |
| Mathuriya, SN | 1 |
| Mohindra, S | 1 |
| Umredkar, AA | 1 |
| Adhikari, S | 1 |
| Gupta, SK | 1 |
| Gupta, V | 1 |
| Reddy, S | 1 |
| Goldman, DR | 1 |
| Kaines, A | 1 |
| Hubschman, JP | 1 |
| Sarraf, D | 1 |
| Baltaci, B | 1 |
| Basar, H | 1 |
| Ozcan, A | 1 |
| Gulhan, Y | 1 |
| Aytunur, CS | 1 |
| Menon, G | 1 |
| Baldawa, SS | 1 |
| Nair, S | 1 |
| Srivastava, VK | 1 |
| Agrawal, S | 1 |
| Sahu, S | 1 |
| Li, QY | 1 |
| Xu, WL | 1 |
| Zhang, Y | 1 |
| Lu, PS | 1 |
| Yuan, ZC | 1 |
| Zhan, LP | 1 |
| Wang, P | 1 |
| Lu, XY | 1 |
| Cheng, B | 1 |
| Chowdhury, FH | 1 |
| Haque, MR | 1 |
| Oskouian, RJ | 1 |
| Martin, NA | 2 |
| Lee, JH | 1 |
| Glenn, TC | 1 |
| Guthrie, D | 1 |
| Gonzalez, NR | 1 |
| Afari, A | 1 |
| Viñuela, F | 2 |
| Lang, EW | 1 |
| Neugebauer, M | 1 |
| Ng, K | 1 |
| Fung, V | 1 |
| Clouston, P | 1 |
| Dorsch, NW | 2 |
| Murayama, Y | 1 |
| Song, JK | 2 |
| Uda, K | 1 |
| Gobin, YP | 1 |
| Duckwiler, GR | 1 |
| Tateshima, S | 1 |
| Patel, AB | 1 |
| DELGUERCIO, R | 1 |
| Scanlon, A | 1 |
| Chang, S | 1 |
| Srinivas, A | 1 |
| Murphy, K | 1 |
| Rath, GP | 1 |
| Prabhakar, H | 1 |
| Dash, HH | 1 |
| Suri, A | 1 |
| Sayama, CM | 1 |
| Liu, JK | 1 |
| Couldwell, WT | 1 |
| Pritz, MB | 2 |
| Abdennour, L | 1 |
| Lejean, L | 1 |
| Bonneville, F | 1 |
| Boch, AL | 1 |
| Puybasset, L | 1 |
| Carter, LP | 1 |
| Erspamer, R | 1 |
| Okumura, T | 2 |
| Oda, Y | 2 |
| Arimitsu, T | 1 |
| Mori, K | 1 |
| Kostron, H | 1 |
| Twerdy, K | 1 |
| Mohsenipour, I | 1 |
| Fischer, J | 1 |
| Kataoka, K | 1 |
| Niiyama, K | 1 |
| Uejima, T | 1 |
| Kuroda, R | 1 |
| Ioku, M | 1 |
| Yamada, K | 1 |
| Taneda, M | 1 |
| Hayakawa, T | 1 |
| McAuliffe, W | 1 |
| Townsend, M | 1 |
| Eskridge, JM | 4 |
| Newell, DW | 3 |
| Grady, MS | 2 |
| Winn, HR | 3 |
| Miller, JA | 1 |
| Cross, DT | 1 |
| Moran, CJ | 1 |
| Dacey, RG | 1 |
| McFarland, JG | 1 |
| Diringer, MN | 1 |
| Tsukahara, T | 3 |
| Yoshimura, S | 2 |
| Kazekawa, K | 3 |
| Hashimoto, N | 2 |
| Giller, CA | 1 |
| Purdy, P | 1 |
| Giller, A | 1 |
| Batjer, HH | 1 |
| Kopitnik, T | 1 |
| Mathis, JM | 2 |
| DeNardo, A | 1 |
| Jensen, ME | 1 |
| Scott, J | 1 |
| Dion, JE | 1 |
| Clouston, JE | 1 |
| Numaguchi, Y | 1 |
| Zoarski, GH | 1 |
| Aldrich, EF | 1 |
| Simard, JM | 1 |
| Zitnay, KM | 1 |
| Barr, JD | 1 |
| Horton, JA | 1 |
| Clyde, BL | 1 |
| Firlik, AD | 2 |
| Kaufmann, AM | 2 |
| Spearman, MP | 1 |
| Yonas, H | 2 |
| Kobayashi, A | 1 |
| McLoughlin, AL | 1 |
| Yoshida, K | 1 |
| Watanabe, H | 1 |
| Nakamura, S | 1 |
| Terada, T | 1 |
| Kinoshita, Y | 1 |
| Yokote, H | 1 |
| Tsuura, M | 1 |
| Nakai, K | 1 |
| Itakura, T | 1 |
| Hyotani, G | 1 |
| Kuriyama, T | 1 |
| Naka, Y | 1 |
| Kido, T | 1 |
| Elliott, JP | 3 |
| Lam, DJ | 1 |
| Douville, CM | 1 |
| Le Roux, PD | 1 |
| Lewis, DH | 1 |
| Mayberg, MR | 1 |
| Fandino, J | 1 |
| Kaku, Y | 2 |
| Schuknecht, B | 1 |
| Valavanis, A | 1 |
| Yonekawa, Y | 2 |
| Chiappetta, F | 1 |
| Brunori, A | 1 |
| Bruni, P | 1 |
| Firlik, KS | 1 |
| Jungreis, CA | 1 |
| Katoh, H | 1 |
| Shima, K | 1 |
| Shimizu, A | 1 |
| Takiguchi, H | 1 |
| Miyazawa, T | 1 |
| Umezawa, H | 1 |
| Nawashiro, H | 1 |
| Ishihara, S | 1 |
| Kaji, T | 1 |
| Makita, K | 1 |
| Tsuchiya, K | 1 |
| Morizane, A | 1 |
| Nakahara, I | 1 |
| Sakai, N | 1 |
| Yanamoto, H | 1 |
| Akiyama, Y | 1 |
| Sakai, H | 1 |
| Higashi, T | 1 |
| Namura, S | 1 |
| Takahashi, J | 1 |
| Nishizaki, J | 1 |
| Kokuzawa, J | 1 |
| Manaka, H | 1 |
| Hayashi, N | 1 |
| Nagata, I | 1 |
| Kikuchi, H | 2 |
| Polin, RS | 1 |
| Coenen, VA | 1 |
| Hansen, CA | 1 |
| Shin, P | 1 |
| Baskaya, MK | 1 |
| Nanda, A | 1 |
| Kassell, NF | 2 |
| Morgan, MK | 2 |
| Jonker, B | 1 |
| Finfer, S | 1 |
| Harrington, T | 1 |
| Wanke, I | 1 |
| Dörfler, A | 1 |
| Dietrich, U | 1 |
| Aalders, T | 1 |
| Forsting, M | 1 |
| Dalbasti, T | 1 |
| Karabiyikoglu, M | 1 |
| Ozdamar, N | 1 |
| Oktar, N | 1 |
| Cagli, S | 1 |
| Reisch, R | 1 |
| Filippi, R | 1 |
| Böcher-Schwarz, H | 1 |
| Mauer, D | 1 |
| Ringel, K | 1 |
| Stoeter, P | 1 |
| Perneczky, A | 1 |
| Minami, H | 1 |
| Kuwamura, K | 1 |
| Tamaki, N | 1 |
| Chia, RY | 1 |
| Hughes, RS | 1 |
| Peterson, EW | 1 |
| Leblanc, R | 1 |
| Searle, R | 1 |
| Mandy, F | 1 |
| Yasargil, MG | 1 |
| Antic, J | 1 |
| Laciga, R | 1 |
| Jain, KK | 1 |
| Hodosh, RM | 1 |
| Smith, RD | 1 |
| Helm, G | 1 |
| Simmons, N | 1 |
| Phillips, CD | 1 |
| Cail, WS | 1 |
| Konishi, T | 1 |
| Kang, Y | 1 |
| Kamijyo, Y | 1 |
| Segawa, H | 1 |
| Saito, I | 1 |
| Okada, T | 1 |
| Nagayama, I | 1 |
| Kitamura, K | 1 |
| Takakura, K | 1 |
| Sano, K | 1 |
| Cummins, BH | 1 |
| Griffith, HB | 1 |
| Thomson, JL | 1 |
| Echlin, FA | 1 |
| Vidovszky, T | 1 |
9 reviews available for papaverine and Intracranial Aneurysm
| Article | Year |
|---|---|
Prolonged Intracisternal Papaverine Toxicity: Index Case Description and Proposed Mechanism of Action.
Topics: Female; Humans; Intracranial Aneurysm; Middle Aged; Papaverine; Vasodilator Agents; Vasospasm, Intra | 2018 |
Association of acute onset hypertension and tachycardia following intracisternal papaverine administration during intracranial aneurysm surgery: a case report and review of the literature.
Topics: Acute Disease; Humans; Hypertension; Intracranial Aneurysm; Male; Middle Aged; Papaverine; Tachycard | 2011 |
Aneurysmal subarachnoid haemorrhage--Part 2: Post-operative nursing management diagnosis, complications and treatment: a composite case study.
Topics: Angioplasty, Balloon; Brain Edema; Female; Humans; Hydrocephalus; Infusions, Intra-Arterial; Intracr | 2004 |
Endovascular management of a patient after SAH.
Topics: Aneurysm, Ruptured; Aortic Dissection; Cerebral Hemorrhage; Clinical Trials as Topic; Embolization, | 2005 |
Update on endovascular therapies for cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage.
Topics: Angioplasty, Balloon; Combined Modality Therapy; Humans; Intracranial Aneurysm; Papaverine; Subarach | 2006 |
Neuroradiologic diagnosis and treatment of vasospasm.
Topics: Angioplasty, Balloon; Brain Ischemia; Combined Modality Therapy; Decision Making; Humans; Injections | 1997 |
Management of intracranial aneurysms: "state of the art".
Topics: Embolization, Therapeutic; Free Radical Scavengers; Humans; Intracranial Aneurysm; Neurology; Papave | 1998 |
Endovascular therapy for aneurysmal vasospasm.
Topics: Aneurysm, Ruptured; Angioplasty, Balloon; Blood Flow Velocity; Cerebral Angiography; Cerebrovascular | 1999 |
Current concepts in the etiology and treatment of vasospasm.
Topics: Animals; Brain Edema; Cerebral Angiography; Cerebral Arteries; Cerebrovascular Circulation; Disease | 1968 |
4 trials available for papaverine and Intracranial Aneurysm
| Article | Year |
|---|---|
Intra-arterial papaverine for the treatment of cerebral vasospasm after subarachnoid hemorrhage.
Topics: Cerebral Angiography; Cerebrovascular Circulation; Humans; Infusions, Intra-Arterial; Intracranial A | 1994 |
Efficacy of transluminal angioplasty for the management of symptomatic cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Angioplasty, Balloon; Combined Modality Therapy; Double-Blind Method; Female; Glasgow C | 2000 |
Aggressive management of aneurysmal subarachnoid haemorrhage based on a papaverine angioplasty protocol.
Topics: Angioplasty, Balloon; Cerebral Arteries; Humans; Intracranial Aneurysm; Papaverine; Recovery of Func | 2000 |
Efficacy of controlled-release papaverine pellets in preventing symptomatic cerebral vasospasm.
Topics: Adult; Delayed-Action Preparations; Drug Implants; Female; Humans; Intracranial Aneurysm; Male; Midd | 2001 |
49 other studies available for papaverine and Intracranial Aneurysm
| Article | Year |
|---|---|
Topical papaverine as rescue therapy for vasospasm complicated by unsecured aneurysm.
Topics: Administration, Topical; Female; Humans; Intracranial Aneurysm; Middle Aged; Papaverine; Vasospasm, | 2014 |
Intra- and post-operational changes in pupils induced by local application of cisternal papaverine during cerebral aneurysm operations.
Topics: Adult; Aged; Carotid Artery, Internal; Cisterna Magna; Female; Humans; Intracranial Aneurysm; Intrao | 2014 |
Transient pupillary dilation following local papaverine application in intracranial aneurysm surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Cerebral Artery; Craniotomy; Female; Functional | 2015 |
Severe hypotension with intracisternal application of papaverine after clipping of an intracranial aneurysm.
Topics: Acute Kidney Injury; Carotid Artery Diseases; Cerebral Angiography; Cisterna Magna; Fatal Outcome; H | 2009 |
Intracisternal irrigation of papaverine leading to choroidal infarction.
Topics: Blindness; Cerebral Angiography; Choroid; Cisterna Magna; Female; Fluorescein Angiography; Humans; I | 2009 |
Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report.
Topics: Bradycardia; Cisterna Magna; Fatal Outcome; Glasgow Coma Scale; Heart Arrest; Hemodynamics; Humans; | 2010 |
Transient oculomotor nerve palsy after topical administration of intracisternal papaverine.
Topics: Administration, Topical; Aneurysm, Ruptured; Cisterna Magna; Dose-Response Relationship, Drug; Human | 2011 |
Intravascular infusion of lidocaine: a novel way to relieve sudden internal carotid artery occlusion in embolization of intracranial aneurysms.
Topics: Aged; Carotid Artery, Internal; Carotid Stenosis; Embolization, Therapeutic; Female; Humans; Infusio | 2012 |
Severe hypotension, cardiac arrest, and death after intracisternal instillation of papaverine during anterior communicating artery aneurysm clipping. A case report.
Topics: Fatal Outcome; Female; Heart Arrest; Humans; Hypotension; Instillation, Drug; Intracranial Aneurysm; | 2013 |
Multimodal quantitation of the effects of endovascular therapy for vasospasm on cerebral blood flow, transcranial doppler ultrasonographic velocities, and cerebral artery diameters.
Topics: Adult; Aneurysm, Ruptured; Angioplasty, Balloon; Blood Flow Velocity; Brain; Cerebral Angiography; C | 2002 |
Facial nerve palsy after intracisternal papaverine application during aneurysm surgery--case report.
Topics: Cisterna Magna; Facial Nerve Diseases; Facial Paralysis; Female; Humans; Intracranial Aneurysm; Midd | 2002 |
Combined endovascular treatment for both intracranial aneurysm and symptomatic vasospasm.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Angioplasty, Balloon; Cerebral Angiography; Comb | 2003 |
[CONSIDERATIONS ON CEREBRAL HEMODYNAMICS STUDIED BY COMPARATIVE RHEOGRAPHIC AND ELECTROENCEPHALOGRAPHIC EXAMINATIONS. II. ACTION OF PAPAVERINE IN SUBJECTS WITH CEREBRAL VASCULAR DISORDERS].
Topics: Brain Neoplasms; Cerebral Hemorrhage; Cerebrovascular Circulation; Cerebrovascular Disorders; Electr | 1963 |
Haemodynamic changes after intracisternal papaverine instillation during intracranial aneurysmal surgery.
Topics: Administration, Topical; Bradycardia; Humans; Hypotension; Intracranial Aneurysm; Intraoperative Com | 2006 |
Contralateral pupillary dilatation after intracisternal papaverine instillation.
Topics: Craniotomy; Diagnosis, Differential; Disease Progression; Functional Laterality; Humans; Intracrania | 2007 |
[Endovascular treatment of vasospasm following subarachnoid aneurysmal haemorrhage].
Topics: Calcium Channel Blockers; Humans; Intracranial Aneurysm; Nicardipine; Nimodipine; Nitroprusside; Pap | 2007 |
Dynamic quantitative assessment of cortical blood flow.
Topics: Animals; Brain Ischemia; Cats; Cerebral Cortex; Cerebrovascular Circulation; Energy Metabolism; Epin | 1980 |
[Sustained-release pellet of vasodilators--basic experiment].
Topics: Delayed-Action Preparations; Diltiazem; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; N | 1984 |
[Cerebral vasospasm: clinical and biochemical aspects and treatment (author's transl)].
Topics: Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Norepinephrine; Papaverine; Phenoxybenzam | 1981 |
Treatment of severe localized cerebral vasospasm following recurrent hemorrhage from middle cerebral artery aneurysm--case report.
Topics: Brain; Cerebral Angiography; Cerebral Arteries; Female; Humans; Intracranial Aneurysm; Ischemic Atta | 1993 |
Intracranial pressure changes induced during papaverine infusion for treatment of vasospasm.
Topics: Adult; Aged; Aneurysm, Ruptured; Angioplasty, Balloon; Blood Pressure; Female; Glasgow Coma Scale; H | 1995 |
Severe thrombocytopenia following intraarterial papaverine administration for treatment of vasospasm.
Topics: Aged; Antibodies; Blood Platelets; Cerebral Angiography; Humans; Infusions, Intra-Arterial; Intracra | 1995 |
Elevated transcranial Doppler ultrasound velocities following therapeutic arterial dilation.
Topics: Adult; Aneurysm, Ruptured; Angioplasty, Balloon; Blood Flow Velocity; Carotid Artery Diseases; Cereb | 1995 |
Transient neurologic events associated with intraarterial papaverine infusion for subarachnoid hemorrhage-induced vasospasm.
Topics: Cerebral Angiography; Female; Humans; Infusions, Intra-Arterial; Intracranial Aneurysm; Ischemic Att | 1994 |
Intraarterial papaverine infusion for cerebral vasospasm after subarachnoid hemorrhage.
Topics: Adult; Aged; Aneurysm, Ruptured; Basilar Artery; Blindness; Carotid Artery, Internal; Cerebral Angio | 1995 |
Transient severe brain stem depression during intraarterial papaverine infusion for cerebral vasospasm.
Topics: Apnea; Basilar Artery; Brain Stem; Female; Humans; Infusions, Intra-Arterial; Intracranial Aneurysm; | 1994 |
Pupillary changes after intracisternal injection of papaverine.
Topics: Adult; Aged; Cisterna Magna; Combined Modality Therapy; Humans; Injections; Intracranial Aneurysm; M | 1994 |
Paradoxical aggravation of vasospasm with papaverine infusion following aneurysmal subarachnoid hemorrhage. Case report.
Topics: Cerebral Angiography; Humans; Intracranial Aneurysm; Ischemic Attack, Transient; Magnetic Resonance | 1996 |
Intra-arterial infusion of papaverine combined with intravenous administration of high-dose nicardipine for cerebral vasospasm.
Topics: Adult; Aged; Aneurysm, Ruptured; Calcium Channel Blockers; Cerebral Angiography; Dose-Response Relat | 1995 |
Intracisternal papaverine administration associated with acute onset of hyperthermia and metabolic acidosis in a craniotomy.
Topics: Acidosis; Adult; Angioplasty; Carotid Arteries; Cerebral Angiography; Cerebral Arteries; Cerebral In | 1997 |
Intraarterial injection of amrinone for vasospasm induced by subarachnoid hemorrhage.
Topics: Adult; Amrinone; Aneurysm, Ruptured; Brain; Cerebral Angiography; Female; Humans; Image Processing, | 1997 |
The effect of endovascular therapy for cerebral arterial spasm, its limitation and pitfalls.
Topics: Adult; Aged; Aneurysm, Ruptured; Angioplasty, Balloon; Cerebral Angiography; Disability Evaluation; | 1997 |
Comparison of balloon angioplasty and papaverine infusion for the treatment of vasospasm following aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Angioplasty, Balloon; Blood Flow Velocity; Cerebral Angiography; Cerebrovascular Circul | 1998 |
Improvement of cerebral oxygenation patterns and metabolic validation of superselective intraarterial infusion of papaverine for the treatment of cerebral vasospasm.
Topics: Acidosis, Lactic; Adult; Aged; Aneurysm, Ruptured; Angioplasty, Balloon; Blood Pressure; Blood Volum | 1998 |
Intra-arterial papaverine for the treatment of cerebral vasospasm following aneurysmal subarachnoid hemorrhage.
Topics: Adult; Aged; Blood Flow Velocity; Cerebral Angiography; Cerebrovascular Circulation; Female; Humans; | 1999 |
Clinical evaluation of the effect of percutaneous transluminal angioplasty and intra-arterial papaverine infusion for the treatment of vasospasm following aneurysmal subarachnoid hemorrhage.
Topics: Angioplasty, Balloon; Evaluation Studies as Topic; Female; Humans; Infusions, Intra-Arterial; Intrac | 1999 |
[Endovascular surgery for untreated ruptured aneurysm with symptomatic vasospasm].
Topics: Aged; Aneurysm, Ruptured; Angioplasty, Balloon; Embolization, Therapeutic; Female; Humans; Intracran | 1999 |
Combined endovascular therapy of ruptured aneurysms and cerebral vasospasm.
Topics: Adult; Aneurysm, Ruptured; Carotid Arteries; Cerebral Angiography; Combined Modality Therapy; Emboli | 2000 |
Effect of intra-arterial infusion of papaverine hydrochloride on brain tissue oxygen pressure in the management of severe vasospasm following aneurysmal subarachnoid hemorrhage.
Topics: Brain; Humans; Injections, Intra-Arterial; Intracranial Aneurysm; Oxygen; Papaverine; Partial Pressu | 2001 |
Intraarterial infusion of papaverine and change of cerebral hemodynamics in symptomatic cerebral vasospasm.
Topics: Adult; Aged; Aged, 80 and over; Angiography; Blood Flow Velocity; Brain; Female; Hemodynamics; Human | 2001 |
Magnesium: a useful adjunct in the prevention of cerebral vasospasm following aneurysmal subarachnoid haemorrhage.
Topics: Adult; Aged; Cerebral Angiography; Female; Humans; Injections, Intra-Arterial; Injections, Intraveno | 2002 |
Some considerations on cerebral vasospasm.
Topics: Administration, Topical; Adrenergic alpha-Antagonists; Animals; Cats; Cerebral Arteries; Cerebral He | 1975 |
Microsurgical pterional approach to aneurysms of the basilar bifurcation.
Topics: Adult; Basilar Artery; Circle of Willis; Humans; Intracranial Aneurysm; Male; Microsurgery; Middle A | 1976 |
Superselective intra-arterial infusion of papaverine for the treatment of cerebral vasospasm after subarachnoid hemorrhage.
Topics: Adult; Aged; Aged, 80 and over; Aneurysm, Ruptured; Angioplasty, Balloon; Female; Humans; Infusions, | 1992 |
Treatment of cerebral vasospasm with intra-arterial papaverine.
Topics: Adult; Aged; Aneurysm, Ruptured; Female; Humans; Infusions, Intra-Arterial; Intracranial Aneurysm; I | 1992 |
[Treatment of vasospasm after ruptured cerebral aneurysms by 'pellet-cisternal-drain: PCD' containing sustained-release vasodilators].
Topics: Adult; Aged; Delayed-Action Preparations; Diltiazem; Drainage; Female; Humans; Intracranial Aneurysm | 1988 |
[Efficacy of intracisternal papaverine on symptomatic vasospasm].
Topics: Cerebral Angiography; Cerebral Hemorrhage; Cisterna Magna; Humans; Injections; Intracranial Aneurysm | 1986 |
Per-operative cerebral angiography.
Topics: Adult; Catheterization; Cerebral Angiography; Cerebrovascular Disorders; Craniotomy; Female; Humans; | 1974 |
[Comparative study on the vasodilatory activities of bencyclane and papaverine by cerebral angiography].
Topics: Adult; Aged; Brain Neoplasms; Cerebral Angiography; Cycloheptanes; Diagnosis, Differential; Female; | 1970 |