papaverine has been researched along with Injuries, Spinal Cord in 34 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was done to evaluate the effectiveness of transdermal nitroglycerin in the treatment of erectile dysfunction in males with spinal cord lesions as compared to the treatment with intracavernous injection of papaverine." | 9.08 | Comparison of transdermal nitroglycerin and intracavernous injection of papaverine in the treatment of erectile dysfunction in patients with spinal cord lesions. ( Kurien, T; Renganathan, R; Suranjan, B, 1997) |
| "To compare the effectiveness of topically applied 2% minoxidil to that of intracorporeal injection therapy and vacuum constriction devices for the treatment of erectile dysfunction in the spinal cord injured (SCI) male." | 7.69 | Prospective comparison of topical minoxidil to vacuum constriction device and intracorporeal papaverine injection in treatment of erectile dysfunction due to spinal cord injury. ( Chancellor, MB; Freedman, MK; Panzer, DE; Rivas, DA; Staas, WE, 1994) |
| "Papaverine was injected into the base of one corpora cavernosum." | 5.29 | Management of impotence due to spinal cord injury using low dose papaverine. ( Chen, D; Lovell, L; Palmer, J; Rayner, S; Roth, EJ; Yarkony, GM, 1995) |
| "The nitroglycerin plasters were applied on the skin of the penile shaft and a positive response was obtained in 12 men." | 5.28 | Transcutaneous nitroglycerin in the treatment of erectile dysfunction in spinal cord injured. ( Biering-Sørensen, F; Sønksen, J, 1992) |
| "This study was done to evaluate the effectiveness of transdermal nitroglycerin in the treatment of erectile dysfunction in males with spinal cord lesions as compared to the treatment with intracavernous injection of papaverine." | 5.08 | Comparison of transdermal nitroglycerin and intracavernous injection of papaverine in the treatment of erectile dysfunction in patients with spinal cord lesions. ( Kurien, T; Renganathan, R; Suranjan, B, 1997) |
| "A total of 66 spinal cord injury patients with erectile dysfunction entered a protocol of penile intracavernous pharmacotherapy with papaverine hydrochloride (30 mg." | 5.06 | Vasoactive intracavernous pharmacotherapy for the treatment of erectile impotence in men with spinal cord injury. ( Cameron, JS; Dykstra, DD; Lange, PH; Reinberg, Y; Sidi, AA, 1987) |
| " The literature search was restricted to articles published in English, French, and Spanish up to November 2014 using the key words alprostadil, papaverine, moxisylite, alpha-blocking agent, phentolamine, intracavernous injection, spinal cord injuries, paraplegia, quadriplegia, and erectile dysfunction." | 4.93 | Intracavernous Injections in Spinal Cord Injured Men With Erectile Dysfunction, a Systematic Review and Meta-Analysis. ( Bonan, I; Chéhensse, C; Chochina, L; Damphousse, M; Giuliano, F; Manunta, A; Naudet, F, 2016) |
| "After laminectomy was performed and contusive spinal cord injuries were induced in adult female Macaca rhesus, three received intrathecal papaverine, and three received saline 0." | 3.74 | Effect of intrathecal papaverine on blood flow and secondary injury in injured cord. ( Huang, L; Huiyong, S; Jie, L; Li, J; Lin, H; Ma, YC; Peng, W; Rui, Y; Shen, HY; Tang, Y; Wang, P; Wei, Y; Wu, YF; Yanfeng, W; Yang, R; Yang, W; Yong, T; Yuanchen, M, 2008) |
| " The authors' pharmacologic erection program, using a fixed combination of prostaglandin E1 (PGE1) and papaverine, is notable for its simplicity and acceptance by patients who have suffered spinal cord injuries (SCIs)." | 3.70 | A simplified pharmacologic erection program for patients with spinal cord injury. ( Britanico, J; Galea, G; Nicolis, C; Vapnek, JM; Zaslau, S, 1999) |
| "Using papaverine, papaverine/phentolamine, or prostaglandin E1 (PGE1), intracavernosal pharmacotherapy has been successful in treating erectile dysfunction." | 3.69 | Experience with intracavernosal tri-mixture for the management of neurogenic erectile dysfunction. ( Chao, R; Clowers, DE, 1994) |
| "To compare the effectiveness of topically applied 2% minoxidil to that of intracorporeal injection therapy and vacuum constriction devices for the treatment of erectile dysfunction in the spinal cord injured (SCI) male." | 3.69 | Prospective comparison of topical minoxidil to vacuum constriction device and intracorporeal papaverine injection in treatment of erectile dysfunction due to spinal cord injury. ( Chancellor, MB; Freedman, MK; Panzer, DE; Rivas, DA; Staas, WE, 1994) |
| " In the current study, we evaluated 40 SCI patients and 116 patients with vascular based impotence who had been followed for a minimum of 1 month while utilising intracavernous injections of phentolamine and papaverine." | 3.67 | Intracavernous pharmacotherapy for management of erectile dysfunction in spinal cord injury. ( Lloyd, LK; Richards, JS, 1989) |
| "We report on our results with the intracavernous injection and self-injection of papaverine-phentolamine in a group of spinal cord injury patients with erectile impotence." | 3.67 | Intracavernous injection of vasoactive drugs, an alternative for treating impotence in spinal cord injury patients. ( Claessens, H; de Meyer, JM; de Sy, WA; Wyndaele, JJ, 1986) |
| "Alprostadil was used 51 times, moxisylite nine times and papaverine four times." | 2.70 | [Intracavernous injections in the treatment of erectile dysfunction in spinal cord injured patients: experience with 36 patients]. ( Boiteau, F; Boyer, F; Dizien, O; Laffont, I; Lebib Ben Achour, S, 2001) |
| "Papaverine was injected into the base of one corpora cavernosum." | 1.29 | Management of impotence due to spinal cord injury using low dose papaverine. ( Chen, D; Lovell, L; Palmer, J; Rayner, S; Roth, EJ; Yarkony, GM, 1995) |
| "The nitroglycerin plasters were applied on the skin of the penile shaft and a positive response was obtained in 12 men." | 1.28 | Transcutaneous nitroglycerin in the treatment of erectile dysfunction in spinal cord injured. ( Biering-Sørensen, F; Sønksen, J, 1992) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 9 (26.47) | 18.7374 |
| 1990's | 19 (55.88) | 18.2507 |
| 2000's | 4 (11.76) | 29.6817 |
| 2010's | 2 (5.88) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Hadiji, N | 1 |
| Benbouzid, R | 1 |
| Previnaire, JG | 1 |
| Leblond, C | 1 |
| Mieusset, R | 1 |
| Enjalbert, M | 1 |
| Soler, JM | 1 |
| Chochina, L | 1 |
| Naudet, F | 1 |
| Chéhensse, C | 1 |
| Manunta, A | 1 |
| Damphousse, M | 1 |
| Bonan, I | 1 |
| Giuliano, F | 1 |
| Denys, P | 1 |
| Ben Smail, D | 1 |
| Even-Schneider, A | 1 |
| Chartier-Kastler, E | 1 |
| Mittmann, N | 1 |
| Craven, BC | 1 |
| Gordon, M | 1 |
| MacMillan, DH | 1 |
| Hassouna, M | 1 |
| Raynard, W | 1 |
| Kaiser, A | 1 |
| Lanctôt, LK | 1 |
| Tarride, JE | 1 |
| Tang, Y | 1 |
| Yong, T | 1 |
| Shen, HY | 1 |
| Huiyong, S | 1 |
| Huang, L | 1 |
| Lin, H | 1 |
| Wu, YF | 1 |
| Yanfeng, W | 1 |
| Yang, W | 1 |
| Wei, Y | 1 |
| Ma, YC | 1 |
| Yuanchen, M | 1 |
| Yang, R | 1 |
| Rui, Y | 1 |
| Li, J | 1 |
| Jie, L | 1 |
| Wang, P | 1 |
| Peng, W | 1 |
| Katoh, Y | 1 |
| Yarkony, GM | 1 |
| Chen, D | 1 |
| Palmer, J | 1 |
| Roth, EJ | 1 |
| Rayner, S | 1 |
| Lovell, L | 1 |
| Otani, T | 1 |
| Kai, S | 1 |
| Narushima, M | 1 |
| Chao, R | 1 |
| Clowers, DE | 1 |
| Chancellor, MB | 3 |
| Rivas, DA | 3 |
| Panzer, DE | 1 |
| Freedman, MK | 1 |
| Staas, WE | 1 |
| Kapoor, VK | 1 |
| Chahal, AS | 1 |
| Jyoti, SP | 1 |
| Mundkur, YJ | 1 |
| Kotwal, SV | 1 |
| Mehta, VK | 1 |
| Yanagi, S | 1 |
| Suzuki, H | 1 |
| Namiki, T | 1 |
| Huang, B | 1 |
| Salzman, SK | 1 |
| Watanabe, T | 1 |
| Hirsch, IH | 1 |
| Bennett, CJ | 1 |
| Finocchiaro, MV | 1 |
| Razi, S | 1 |
| Bennett, JK | 1 |
| Green, BG | 1 |
| Foote, JE | 1 |
| Killorian, RW | 1 |
| Juma, S | 1 |
| Linsenmeyer, TA | 2 |
| Lloyd, K | 1 |
| Renganathan, R | 1 |
| Suranjan, B | 1 |
| Kurien, T | 1 |
| Svensson, LG | 1 |
| Zaslau, S | 1 |
| Nicolis, C | 1 |
| Galea, G | 1 |
| Britanico, J | 1 |
| Vapnek, JM | 1 |
| Lebib Ben Achour, S | 1 |
| Laffont, I | 1 |
| Boyer, F | 1 |
| Boiteau, F | 1 |
| Dizien, O | 1 |
| Rivlin, AS | 1 |
| Tator, CH | 1 |
| Biering-Sørensen, F | 3 |
| Sønksen, J | 2 |
| Jaworski, TM | 1 |
| Richards, JS | 2 |
| Lloyd, LK | 2 |
| Bodner, DR | 2 |
| Leffler, B | 1 |
| Frost, F | 1 |
| Earle, CM | 1 |
| Keogh, EJ | 1 |
| Ker, JK | 1 |
| Cherry, DJ | 1 |
| Tulloch, AG | 1 |
| Lord, DJ | 1 |
| Schurch, B | 1 |
| Kuhn, W | 1 |
| Sønksen, JO | 1 |
| Hansen, EF | 1 |
| Colstrup, H | 1 |
| Sidi, AA | 1 |
| Cameron, JS | 1 |
| Dykstra, DD | 1 |
| Reinberg, Y | 1 |
| Lange, PH | 1 |
| Yamagishi, M | 1 |
| Lindan, R | 1 |
| Leffler, E | 1 |
| Kursh, ED | 1 |
| Resnick, MI | 1 |
| Momose, H | 1 |
| Natsume, O | 1 |
| Yamamoto, M | 1 |
| Suemori, T | 1 |
| Yamada, K | 1 |
| Wyndaele, JJ | 1 |
| de Meyer, JM | 1 |
| de Sy, WA | 1 |
| Claessens, H | 1 |
| Seifert, J | 1 |
| Lob, G | 1 |
| Stoephasius, E | 1 |
| Probst, J | 1 |
| Brendel, W | 1 |
4 reviews available for papaverine and Injuries, Spinal Cord
| Article | Year |
|---|---|
Intracavernous Injections in Spinal Cord Injured Men With Erectile Dysfunction, a Systematic Review and Meta-Analysis.
Topics: Alprostadil; Erectile Dysfunction; Humans; Male; Moxisylyte; Papaverine; Penile Erection; Prospectiv | 2016 |
[Genito-sexual dysfunction in patients with a medullary lesion].
Topics: Adult; Electric Stimulation Therapy; Erectile Dysfunction; Humans; Insemination, Artificial; Male; P | 2004 |
Penile erection in men with spinal cord or cauda equina lesions.
Topics: Adult; Cauda Equina; Equipment and Supplies; Erectile Dysfunction; Female; Humans; Male; Nitroglycer | 1992 |
Evaluation and treatment of erectile dysfunction following spinal cord injury: a review.
Topics: Equipment Design; Humans; Injections; Male; Papaverine; Penile Erection; Penile Prosthesis; Penis; P | 1991 |
3 trials available for papaverine and Injuries, Spinal Cord
| Article | Year |
|---|---|
Comparison of transdermal nitroglycerin and intracavernous injection of papaverine in the treatment of erectile dysfunction in patients with spinal cord lesions.
Topics: Administration, Cutaneous; Adult; Cross-Over Studies; Erectile Dysfunction; Humans; Injections; Male | 1997 |
[Intracavernous injections in the treatment of erectile dysfunction in spinal cord injured patients: experience with 36 patients].
Topics: Adult; Alprostadil; Erectile Dysfunction; Humans; Male; Moxisylyte; Papaverine; Patient Satisfaction | 2001 |
Vasoactive intracavernous pharmacotherapy for the treatment of erectile impotence in men with spinal cord injury.
Topics: Adult; Clinical Trials as Topic; Drug Combinations; Erectile Dysfunction; Follow-Up Studies; Humans; | 1987 |
27 other studies available for papaverine and Injuries, Spinal Cord
| Article | Year |
|---|---|
[Evaluation of the management of erectile and ejaculatory dysfunction in a series of 90 patients with spinal cord injuries].
Topics: Adolescent; Adrenergic alpha-Agonists; Adult; Aged; Alprostadil; Ejaculation; Erectile Dysfunction; | 2013 |
Erectile dysfunction in spinal cord injury: a cost-utility analysis.
Topics: Adrenergic alpha-Antagonists; Adult; Aged; Alprostadil; Cost-Benefit Analysis; Drug Costs; Erectile | 2005 |
Effect of intrathecal papaverine on blood flow and secondary injury in injured cord.
Topics: Animals; Blood Flow Velocity; Disease Models, Animal; Female; Injections, Spinal; Laminectomy; Laser | 2008 |
[A study of regional circulation of cervical spinal cord after acute experimental spinal contusion (author's transl)].
Topics: Animals; Blood Pressure; Cats; Contusions; Neck; Papaverine; Regional Blood Flow; Spinal Cord; Spina | 1980 |
Management of impotence due to spinal cord injury using low dose papaverine.
Topics: Adult; Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; Male; Papaverine; Sexual Beha | 1995 |
Ejaculation obtained by intracavernous papaverine in a cervical spinal cord injury patient resulting in pregnancy and childbirth. Case report.
Topics: Adult; Ejaculation; Electric Stimulation; Female; Humans; Injections; Male; Papaverine; Penis; Pregn | 1994 |
Experience with intracavernosal tri-mixture for the management of neurogenic erectile dysfunction.
Topics: Adult; Alprostadil; Cost-Benefit Analysis; Drug Combinations; Drug Costs; Drug Monitoring; Drug Syne | 1994 |
Prospective comparison of topical minoxidil to vacuum constriction device and intracorporeal papaverine injection in treatment of erectile dysfunction due to spinal cord injury.
Topics: Administration, Topical; Adult; Aged; Combined Modality Therapy; Constriction; Erectile Dysfunction; | 1994 |
Intracavernous papaverine for impotence in spinal cord injured patients.
Topics: Adult; Erectile Dysfunction; Humans; Injections; Male; Middle Aged; Papaverine; Penile Erection; Pen | 1993 |
[Evaluation of vasculogenic erectile impotence using DICC (dynamic infusion cavernosometry & cevernosography) with intracavernous injection of papaverine].
Topics: Adult; Aged; Erectile Dysfunction; Humans; Injections; Male; Manometry; Middle Aged; Papaverine; Pen | 1993 |
Erectile response to topical, intraurethral and intracorporal pharmacotherapy in a rat model of spinal cord injury.
Topics: Administration, Topical; Animals; Male; Minoxidil; Nitroglycerin; Papaverine; Penile Erection; Penis | 1995 |
Epidemiology of current treatment for sexual dysfunction in spinal cord injured men in the USA model spinal cord injury centers.
Topics: Adolescent; Adult; Aged; Alprostadil; Humans; Impotence, Vasculogenic; Male; Middle Aged; Papaverine | 1996 |
An approach to spinal cord protection during descending or thoracoabdominal aortic repairs.
Topics: Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Drainage; Humans; Hypothermia, Induced; Ische | 1999 |
A simplified pharmacologic erection program for patients with spinal cord injury.
Topics: Adult; Aged; Alprostadil; Erectile Dysfunction; Humans; Injections; Male; Middle Aged; Papaverine; P | 1999 |
Effect of vasodilators and myelotomy on recovery after acute spinal cord injury in rats.
Topics: Animals; Epinephrine; Female; Nitroprusside; Papaverine; Rats; Spinal Cord; Spinal Cord Injuries; Va | 1979 |
Retrospective review of sexual and marital satisfaction of spinal cord injury and diabetic males post penile injection or implant.
Topics: Adult; Diabetes Mellitus; Drug Therapy, Combination; Humans; Injections; Male; Marriage; Middle Aged | 1992 |
Transcutaneous nitroglycerin in the treatment of erectile dysfunction in spinal cord injured.
Topics: Administration, Cutaneous; Adult; Aging; Erectile Dysfunction; Humans; Male; Middle Aged; Nitroglyce | 1992 |
The role of intracavernous injection of vasoactive medications for the restoration of erection in spinal cord injured males: a three year follow up.
Topics: Adult; Aged; Erectile Dysfunction; Female; Humans; Injections; Male; Middle Aged; Papaverine; Penile | 1992 |
The role of intracavernosal vasoactive agents to overcome impotence due to spinal cord injury.
Topics: Adult; Alprostadil; Blood Pressure; Erectile Dysfunction; Humans; Injections; Male; Middle Aged; Pap | 1992 |
[Erectile dysfunction of male spinal cord injury patients].
Topics: Adult; Alprostadil; Ejaculation; Erectile Dysfunction; Humans; Injections; Male; Middle Aged; Papave | 1990 |
[Intracavernous self-injection for treatment of erectile dysfunction inpatients with spinal cord injuries].
Topics: Administration, Topical; Adolescent; Adult; Aged; Erectile Dysfunction; Humans; Injections; Male; Mi | 1990 |
Intracavernous pharmacotherapy for management of erectile dysfunction in spinal cord injury.
Topics: Adult; Dose-Response Relationship, Drug; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine | 1989 |
[The blood flow in normal and injured spinal cord--experimental studies by the heat clearance method].
Topics: Animals; Aorta, Thoracic; Carbon Dioxide; Dogs; Homeostasis; Hot Temperature; Papaverine; Regional B | 1987 |
The application of intracavernous injection of vasoactive medications for erection in men with spinal cord injury.
Topics: Adult; Drug Combinations; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Penile Erecti | 1987 |
[Intracavernous injection of papaverine hydrochloride for impotence in patients with spinal cord injury].
Topics: Adult; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Penile Erection; Penis; Spinal C | 1987 |
Intracavernous injection of vasoactive drugs, an alternative for treating impotence in spinal cord injury patients.
Topics: Drug Combinations; Erectile Dysfunction; Humans; Injections; Male; Papaverine; Penis; Phentolamine; | 1986 |
[Possibilities of increasing the blood circulation in the muscle. Comparative studies in patients with paraplegic spinal injuries].
Topics: Blood Volume; Humans; Muscles; Papaverine; Paraplegia; Physical Therapy Modalities; Regional Blood F | 1974 |