papaverine has been researched along with Immunoglobulin Light-chain Amyloidosis in 1 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Immunoglobulin Light-chain Amyloidosis: A nonproliferative disorder of the PLASMA CELL characterized by excessive production and misfolding of IMMUNOGLOBULIN LIGHT CHAINS that form insoluble amyloid fibrils (see AMYLOID DEPOSITS) in various tissues. Clinical features include LIVER FAILURE; MULTIPLE MYELOMA; NEPHROTIC SYNDROME; RESTRICTIVE CARDIOMYOPATHY, and neuropathies.
| Excerpt | Relevance | Reference |
|---|---|---|
| "NLGM1 protects against LC-induced human microvascular endothelial dysfunction through increased nitric oxide bioavailability and reduced oxidative and nitrative stress mediated by Nrf-2-dependent antioxidant stress response." | 1.43 | Monosialoganglioside-Containing Nanoliposomes Restore Endothelial Function Impaired by AL Amyloidosis Light Chain Proteins. ( Blancas-Mejia, LM; Burciu, C; Franco, DA; Guzman-Villanueva, D; Hari, P; Karamanova, N; Lindsay, S; Migrino, RQ; Ramirez-Alvarado, M; Senapati, S; Truran, S; Weissig, V, 2016) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Franco, DA | 1 |
| Truran, S | 1 |
| Weissig, V | 1 |
| Guzman-Villanueva, D | 1 |
| Karamanova, N | 1 |
| Senapati, S | 1 |
| Burciu, C | 1 |
| Ramirez-Alvarado, M | 1 |
| Blancas-Mejia, LM | 1 |
| Lindsay, S | 1 |
| Hari, P | 1 |
| Migrino, RQ | 1 |
1 other study available for papaverine and Immunoglobulin Light-chain Amyloidosis
| Article | Year |
|---|---|
Monosialoganglioside-Containing Nanoliposomes Restore Endothelial Function Impaired by AL Amyloidosis Light Chain Proteins.
Topics: Adipose Tissue; Arterioles; Cell Survival; Cholesterol; Drug Combinations; Endothelial Cells; Endoth | 2016 |