papaverine has been researched along with Hypotension in 23 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Hypotension: Abnormally low BLOOD PRESSURE that can result in inadequate blood flow to the brain and other vital organs. Common symptom is DIZZINESS but greater negative impacts on the body occur when there is prolonged depravation of oxygen and nutrients.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study assessed the feasibility of augmenting cerebral blood flow (CBF) and decreasing hemispheric cerebrovascular resistance (CVR) by intracarotid papaverine during acute cerebral hypotension." | 9.09 | Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension. ( Duong, DH; Hacein-Bey, L; Hacien-Bey, L; Hashimoto, T; James, DJ; Joshi, S; Marshall, RS; Ostapkovich, N; Pile-Spellman, J; Young, WL, 2001) |
| "Cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage is still a leading cause of morbidity and death." | 5.36 | Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report. ( Aytunur, CS; Baltaci, B; Basar, H; Gulhan, Y; Ozcan, A, 2010) |
| "Here, we describe a case of anterior communicating artery aneurysm with hydrocephalus." | 5.33 | Haemodynamic changes after intracisternal papaverine instillation during intracranial aneurysmal surgery. ( Dash, HH; Prabhakar, H; Rath, GP; Suri, A, 2006) |
| "This study assessed the feasibility of augmenting cerebral blood flow (CBF) and decreasing hemispheric cerebrovascular resistance (CVR) by intracarotid papaverine during acute cerebral hypotension." | 5.09 | Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension. ( Duong, DH; Hacein-Bey, L; Hacien-Bey, L; Hashimoto, T; James, DJ; Joshi, S; Marshall, RS; Ostapkovich, N; Pile-Spellman, J; Young, WL, 2001) |
| " Papaverine (10 mg/kg) caused hypotension and increased PRA." | 3.66 | Renin response to hemorrhage and hypotension in the aglomerular toadfish Opsanus tau. ( Lunde, LG; Nishimura, H; Zucker, A, 1979) |
| "Cerebral vasospasm induced by aneurysmal subarachnoid hemorrhage is still a leading cause of morbidity and death." | 1.36 | Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report. ( Aytunur, CS; Baltaci, B; Basar, H; Gulhan, Y; Ozcan, A, 2010) |
| "Here, we describe a case of anterior communicating artery aneurysm with hydrocephalus." | 1.33 | Haemodynamic changes after intracisternal papaverine instillation during intracranial aneurysmal surgery. ( Dash, HH; Prabhakar, H; Rath, GP; Suri, A, 2006) |
| "In yohimbine-treated dogfish, papaverine treatment elicited marked decreases in PCA, RS, and Q, and increases in plasma Ang II and catecholamines." | 1.30 | Cardiovascular control via angiotensin II and circulating catecholamines in the spiny dogfish, Squalus acanthias. ( Bernier, NJ; Gilmour, KM; Perry, SF; Takei, Y, 1999) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 10 (43.48) | 18.7374 |
| 1990's | 5 (21.74) | 18.2507 |
| 2000's | 6 (26.09) | 29.6817 |
| 2010's | 2 (8.70) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Singla, N | 1 |
| Mathuriya, SN | 1 |
| Mohindra, S | 1 |
| Umredkar, AA | 1 |
| Adhikari, S | 1 |
| Gupta, SK | 1 |
| Gupta, V | 1 |
| Baltaci, B | 1 |
| Basar, H | 1 |
| Ozcan, A | 1 |
| Gulhan, Y | 1 |
| Aytunur, CS | 1 |
| Chowdhury, FH | 1 |
| Haque, MR | 1 |
| Butler, DG | 1 |
| Zhang, DH | 1 |
| Villadiego, R | 1 |
| Oudit, GY | 1 |
| Youson, JH | 1 |
| Cadinouche, MZ | 1 |
| ENDERS, A | 1 |
| SCHMIDT, L | 1 |
| MISKO, JC | 1 |
| Mikhailichenko, LA | 1 |
| Timkina, MI | 1 |
| Rath, GP | 1 |
| Prabhakar, H | 1 |
| Dash, HH | 1 |
| Suri, A | 1 |
| Gygax, P | 4 |
| Wiernsperger, N | 4 |
| Cernacek, P | 1 |
| Stewart, DJ | 1 |
| Levy, M | 1 |
| Svensson, LG | 1 |
| Hess, KR | 1 |
| D'Agostino, RS | 1 |
| Entrup, MH | 1 |
| Hreib, K | 1 |
| Kimmel, WA | 1 |
| Nadolny, E | 1 |
| Shahian, DM | 1 |
| Shiode, N | 1 |
| Kato, M | 1 |
| Nakayama, K | 1 |
| Shinohara, K | 1 |
| Kurokawa, J | 1 |
| Yamagata, T | 1 |
| Matsuura, H | 1 |
| Kajiyama, G | 1 |
| Bernier, NJ | 2 |
| Kaiya, H | 1 |
| Takei, Y | 2 |
| Perry, SF | 2 |
| Gilmour, KM | 1 |
| Osadchiĭ, LI | 1 |
| Balueva, TV | 1 |
| Sergeev, IV | 1 |
| Joshi, S | 1 |
| Hashimoto, T | 1 |
| Ostapkovich, N | 1 |
| Pile-Spellman, J | 1 |
| Duong, DH | 1 |
| Hacein-Bey, L | 1 |
| Hacien-Bey, L | 1 |
| Marshall, RS | 1 |
| James, DJ | 1 |
| Young, WL | 1 |
| Benzi, G | 1 |
| Nishimura, H | 1 |
| Lunde, LG | 1 |
| Zucker, A | 1 |
| Danzeisen, M | 1 |
| Schweizer, A | 1 |
| Grandchamp, A | 1 |
| Ayer, G | 1 |
| Truniger, B | 1 |
| Clarke, RS | 1 |
| Dundee, JW | 1 |
| Carson, IW | 1 |
| Arora, MV | 1 |
| McCaughey, W | 1 |
2 trials available for papaverine and Hypotension
| Article | Year |
|---|---|
Reduction of neurologic injury after high-risk thoracoabdominal aortic operation.
Topics: Adult; Aged; Aortic Aneurysm, Abdominal; Aortic Aneurysm, Thoracic; Cardiopulmonary Bypass; Cerebros | 1998 |
Effect of intracarotid papaverine on human cerebral blood flow and vascular resistance during acute hemispheric arterial hypotension.
Topics: Aged; Carotid Arteries; Carotid Stenosis; Cerebrovascular Circulation; Female; Functional Laterality | 2001 |
21 other studies available for papaverine and Hypotension
| Article | Year |
|---|---|
Severe hypotension with intracisternal application of papaverine after clipping of an intracranial aneurysm.
Topics: Acute Kidney Injury; Carotid Artery Diseases; Cerebral Angiography; Cisterna Magna; Fatal Outcome; H | 2009 |
Cardiac arrest after intracisternal papaverine instillation during intracranial aneurysm surgery. Case report.
Topics: Bradycardia; Cisterna Magna; Fatal Outcome; Glasgow Coma Scale; Heart Arrest; Hemodynamics; Humans; | 2010 |
Severe hypotension, cardiac arrest, and death after intracisternal instillation of papaverine during anterior communicating artery aneurysm clipping. A case report.
Topics: Fatal Outcome; Female; Heart Arrest; Humans; Hypotension; Instillation, Drug; Intracranial Aneurysm; | 2013 |
Response by the corpuscles of Stannius to hypotensive stimuli in three divergent ray-finned fishes (Amia calva, Anguilla rostrata, and Catastomus commersoni): cardiovascular and morphological changes.
Topics: Anguilla; Animals; Blood Pressure; Calibration; Cytoplasmic Granules; Elasmobranchii; Endocrine Glan | 2003 |
[Increase of the hypotensive effects of papaverine by epinephrine].
Topics: Epinephrine; Humans; Hypotension; Papaverine | 1952 |
SELECTIVE CEREBRAL HYPOTHERMIA: PHYSIOLOGY AND TECHNIC.
Topics: Blood; Brain; Brain Ischemia; Dogs; Electrocardiography; Hydrogen-Ion Concentration; Hypotension; Hy | 1965 |
Microvessels of hamster buccal pouch under conditions of reduced systemic blood pressure.
Topics: Animals; Caffeine; Cheek; Cricetinae; Hypotension; Male; Papaverine; Probability | 2004 |
Haemodynamic changes after intracisternal papaverine instillation during intracranial aneurysmal surgery.
Topics: Administration, Topical; Bradycardia; Humans; Hypotension; Intracranial Aneurysm; Intraoperative Com | 2006 |
Hypotension induced changes in cerebral microflow and EEG and their pharmacological alterations.
Topics: Animals; Blood Pressure; Brain Ischemia; Cats; Cerebrovascular Circulation; Electroencephalography; | 1983 |
Plasma endothelin-1 response to acute hypotension induced by vasodilating agents.
Topics: Animals; Atrial Natriuretic Factor; Blood Glucose; Blood Pressure; Cyclic GMP; Dogs; Endothelins; Fe | 1994 |
Effect of adenosine triphosphate on human coronary circulation.
Topics: Adenosine Triphosphate; Blood Flow Velocity; Cardiac Catheterization; Chest Pain; Coronary Angiograp | 1998 |
Mediation of humoral catecholamine secretion by the renin-angiotensin system in hypotensive rainbow trout (Oncorhynchus mykiss).
Topics: Acute Disease; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Cardiac Output; Ca | 1999 |
Cardiovascular control via angiotensin II and circulating catecholamines in the spiny dogfish, Squalus acanthias.
Topics: Adrenergic alpha-Antagonists; Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Car | 1999 |
[Effect of hypotension on the arterial system responsiveness].
Topics: Adrenergic alpha-Agonists; Animals; Antihypertensive Agents; Arteries; Blood Pressure; Hypotension; | 2000 |
An analysis of the drugs acting on cerebral energy metabolism.
Topics: Adenine Nucleotides; Amobarbital; Animals; Bemegride; Brain; Dipyridamole; Dogs; Energy Metabolism; | 1975 |
Oligemic-hypotension-induced changes in EEG,CBF and pO2 and their pharmacological modifications.
Topics: Animals; Blood Volume; Cats; Cerebrovascular Circulation; Electroencephalography; Ergolines; Hypoten | 1977 |
Renin response to hemorrhage and hypotension in the aglomerular toadfish Opsanus tau.
Topics: Angiotensinogen; Animals; Female; Fishes; Hematocrit; Hemorrhage; Hypotension; Male; Minoxidil; Papa | 1979 |
Cortical pO2 distribution during oligemic hypotension and its pharmacological modifications.
Topics: Animals; Blood Volume; Cats; Cerebrovascular Circulation; Dihydroergotoxine; Hypotension; Male; Oxyg | 1978 |
Effect of papaverine on cerebral microflow, EEG and pO2 in arterial hypotension.
Topics: Animals; Cats; Cerebrovascular Circulation; Electroencephalography; Hypotension; Microcirculation; O | 1977 |
Pathogenesis of redistribution of intrarenal blood flow in haemorrhagic hypotension.
Topics: Acetylcholine; Angiotensin II; Animals; Autoradiography; Blood Flow Velocity; Dogs; Hypotension; Isc | 1971 |
Clinical studies of induction agents. XL. Althesin with various premedicants.
Topics: Anesthesia, Intravenous; Anesthetics; Atropine; Diazepam; Female; Humans; Hypotension; Ketones; Mepe | 1972 |