papaverine has been researched along with Hypertrophy in 6 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Hypertrophy: General increase in bulk of a part or organ due to CELL ENLARGEMENT and accumulation of FLUIDS AND SECRETIONS, not due to tumor formation, nor to an increase in the number of cells (HYPERPLASIA).
| Excerpt | Relevance | Reference |
|---|---|---|
| "Hyperhomocysteinemia was induced in DDAH1 transgenic (DDAH1 Tg) mice and wild-type littermates using a high methionine/low folate (HM/LF) diet." | 7.76 | Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. ( Arning, E; Baumbach, GL; Bottiglieri, T; Cooke, JP; Dayoub, H; Faraci, FM; Kimoto, M; Lentz, SR; Lynch, CM; Murry, DJ; Rodionov, RN; Stevens, JW; Wilson, KM, 2010) |
| "Hyperhomocysteinemia was induced in DDAH1 transgenic (DDAH1 Tg) mice and wild-type littermates using a high methionine/low folate (HM/LF) diet." | 3.76 | Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. ( Arning, E; Baumbach, GL; Bottiglieri, T; Cooke, JP; Dayoub, H; Faraci, FM; Kimoto, M; Lentz, SR; Lynch, CM; Murry, DJ; Rodionov, RN; Stevens, JW; Wilson, KM, 2010) |
| "To examine the role played by angiotensin II (AII) in the development of prehypertensive vascular hypertrophy in the spontaneously hypertensive rat (SHR) and to determine whether normalization of prehypertensive vascular hypertrophy attenuates the development of hypertension." | 3.69 | Role of angiotensin II in early cardiovascular growth and vascular amplifier development in spontaneously hypertensive rats. ( Black, MJ; Bobik, A; Kanellakis, P, 1997) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (16.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rodionov, RN | 1 |
| Dayoub, H | 1 |
| Lynch, CM | 1 |
| Wilson, KM | 1 |
| Stevens, JW | 1 |
| Murry, DJ | 1 |
| Kimoto, M | 1 |
| Arning, E | 1 |
| Bottiglieri, T | 1 |
| Cooke, JP | 1 |
| Baumbach, GL | 1 |
| Faraci, FM | 1 |
| Lentz, SR | 1 |
| Henriksen, O | 1 |
| Skagen, K | 1 |
| Amtorp, O | 1 |
| Hartling, O | 1 |
| De Rose, AF | 1 |
| Oppezzi, GF | 1 |
| Scotto, S | 1 |
| Black, MJ | 1 |
| Kanellakis, P | 1 |
| Bobik, A | 1 |
| Grossman, HJ | 1 |
| Grossman, VL | 1 |
| Bhathal, PS | 1 |
| Abozeid, M | 1 |
| Juenemann, KP | 1 |
| Luo, JA | 1 |
| Lue, TF | 1 |
| Yen, TS | 1 |
| Tanagho, EA | 1 |
6 other studies available for papaverine and Hypertrophy
| Article | Year |
|---|---|
Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia.
Topics: Acetylcholine; Amidohydrolases; Animals; Arginine; Arterioles; Carotid Artery Thrombosis; Cerebral A | 2010 |
Augmented vasoconstrictor response to changes in vascular transmural pressure in patients with essential arterial hypertension.
Topics: Adult; Female; Follow-Up Studies; Humans; Hypertension; Hypertrophy; Male; Middle Aged; Muscle, Smoo | 1981 |
[Local complications of papaverine-induced erection: follow-up at 7 years].
Topics: Adult; Aged; Erectile Dysfunction; Fibrosis; Follow-Up Studies; Humans; Hypertrophy; Male; Middle Ag | 1993 |
Role of angiotensin II in early cardiovascular growth and vascular amplifier development in spontaneously hypertensive rats.
Topics: Angiotensin II; Angiotensin-Converting Enzyme Inhibitors; Animals; Animals, Newborn; Antihypertensiv | 1997 |
The effect of hepatocyte enlargement on the hemodynamic characteristics of the isolated perfused rat liver preparation.
Topics: Animals; Body Weight; Dose-Response Relationship, Drug; Hypertrophy; Hypotonic Solutions; In Vitro T | 1998 |
Chronic papaverine treatment: the effect of repeated injections on the simian erectile response and penile tissue.
Topics: Animals; Dose-Response Relationship, Drug; Fibrosis; Hypertrophy; Injections; Liver; Macaca fascicul | 1987 |