papaverine has been researched along with Hypertrophy, Left Ventricular in 3 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Hypertrophy, Left Ventricular: Enlargement of the LEFT VENTRICLE of the heart. This increase in ventricular mass is attributed to sustained abnormal pressure or volume loads and is a contributor to cardiovascular morbidity and mortality.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Coronary arterial diameter, cross-sectional area and blood flow velocity were measured during coronary arteriography before and after intracoronary papaverine in 26 control subjects, 45 patients with significant coronary artery disease (> 50% luminal narrowing), 16 patients with syndrome X and 14 patients with hypertension and left ventricular hypertrophy (LVH)." | 3.69 | Abnormal coronary flow reserve in patients with angina pectoris and hypertensive left ventricular hypertrophy. ( Cai, X; Gong, L; Shen, W; Zhang, D; Zhang, X; Zheng, A, 1996) |
| "Myocardial ischemia is associated with impaired endothelium-independent vasodilation of resistance coronary arteries and increased minimal coronary resistance." | 1.32 | Contribution of increased minimal coronary resistance and attenuated vascular adaptive remodeling to myocardial ischemia in patients with systemic hypertension and ventricular hypertrophy. ( Fukudome, T; Hamasaki, S; Ishida, S; Kataoka, T; Minagoe, S; Mizoguchi, E; Ninomiya, Y; Okui, H; Otsuji, Y; Saihara, K; Shinsato, T; Tei, C, 2004) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 2 (66.67) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kataoka, T | 1 |
| Hamasaki, S | 1 |
| Ishida, S | 1 |
| Saihara, K | 1 |
| Okui, H | 1 |
| Fukudome, T | 1 |
| Shinsato, T | 1 |
| Mizoguchi, E | 1 |
| Ninomiya, Y | 1 |
| Otsuji, Y | 1 |
| Minagoe, S | 1 |
| Tei, C | 1 |
| Klauss, V | 1 |
| Meissner, O | 1 |
| Metz, J | 1 |
| Theisen, K | 1 |
| Mudra, H | 1 |
| Shen, W | 1 |
| Cai, X | 1 |
| Zhang, D | 1 |
| Zhang, X | 1 |
| Zheng, A | 1 |
| Gong, L | 1 |
1 trial available for papaverine and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
[Contrast echocardiography in the evaluation of myocardial flow reserve].
Topics: Adult; Aged; Contrast Media; Coronary Circulation; Coronary Disease; Echocardiography; Female; Hemod | 1993 |
2 other studies available for papaverine and Hypertrophy, Left Ventricular
| Article | Year |
|---|---|
Contribution of increased minimal coronary resistance and attenuated vascular adaptive remodeling to myocardial ischemia in patients with systemic hypertension and ventricular hypertrophy.
Topics: Acetylcholine; Aged; Blood Flow Velocity; Cardiac Volume; Coronary Angiography; Coronary Artery Dise | 2004 |
Abnormal coronary flow reserve in patients with angina pectoris and hypertensive left ventricular hypertrophy.
Topics: Angina Pectoris; Blood Flow Velocity; Coronary Circulation; Female; Humans; Hypertension; Hypertroph | 1996 |