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papaverine and Hypertension, Pulmonary

papaverine has been researched along with Hypertension, Pulmonary in 10 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Hypertension, Pulmonary: Increased VASCULAR RESISTANCE in the PULMONARY CIRCULATION, usually secondary to HEART DISEASES or LUNG DISEASES.

Research

Studies (10)

TimeframeStudies, this research(%)All Research%
pre-19904 (40.00)18.7374
1990's3 (30.00)18.2507
2000's1 (10.00)29.6817
2010's2 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Huang, YY1
Yu, YF1
Zhang, C1
Chen, Y1
Zhou, Q1
Li, Z2
Zhou, S1
Guo, L1
Wu, D1
Wu, Y1
Luo, HB1
Tian, X1
Vroom, C1
Ghofrani, HA1
Weissmann, N1
Bieniek, E1
Grimminger, F1
Seeger, W1
Schermuly, RT1
Pullamsetti, SS1
Shevchenko, RN1
Gavrisiuk, VK1
Spyker, D1
Love, LA1
Brooks, SM1
Martinez-Lemus, LA1
Hester, RK1
Becker, EJ1
Jeffrey, JS1
Odom, TW1
Koch, HJ1
Raschka, C1
Shirai, M1
Ninomiya, I1
Sada, K1
Zimon, IN1
Sen'kin, VV1
Miasnik, BN1
Zaslavskaia, RM1
Simonian, AT1
Melik-Adamian, AA1
Topchian, AA1
Parsian, SD1

Other Studies

10 other studies available for papaverine and Hypertension, Pulmonary

ArticleYear
Validation of Phosphodiesterase-10 as a Novel Target for Pulmonary Arterial Hypertension via Highly Selective and Subnanomolar Inhibitors.
    Journal of medicinal chemistry, 2019, 04-11, Volume: 62, Issue:7

    Topics: Animals; Crystallography, X-Ray; Humans; Hypertension, Pulmonary; Male; Molecular Dynamics Simulatio

2019
Phosphodiesterase 10A upregulation contributes to pulmonary vascular remodeling.
    PloS one, 2011, Apr-11, Volume: 6, Issue:4

    Topics: Animals; Cell Proliferation; Cyclic AMP; Cyclic AMP Response Element-Binding Protein; Cyclic Nucleot

2011
[The role of pharmacological tests in the early diagnosis of pulmonary hypertension].
    Vrachebnoe delo, 1983, Issue:8

    Topics: Aminophylline; Humans; Hypertension, Pulmonary; Papaverine; Time Factors

1983
An outbreak of pulmonary poisoning.
    Journal of toxicology. Clinical toxicology, 1996, Volume: 34, Issue:1

    Topics: Asthma; Consumer Product Safety; Cryptogenic Organizing Pneumonia; Disease Outbreaks; Female; Humans

1996
Pulmonary artery endothelium-dependent vasodilation is impaired in a chicken model of pulmonary hypertension.
    The American journal of physiology, 1999, Volume: 277, Issue:1

    Topics: Acetylcholine; Animals; Arginine; Calcimycin; Chickens; Disease Models, Animal; Endothelium, Vascula

1999
Papaverine, a vasodilator with antiviral activity.
    Swiss medical weekly, 2002, Feb-23, Volume: 132, Issue:7-8

    Topics: Adult; HIV Infections; Humans; Hypertension, Pulmonary; Papaverine; Vasodilator Agents

2002
Constrictor response of small pulmonary arteries to acute pulmonary hypertension during left atrial pressure elevation.
    The Japanese journal of physiology, 1991, Volume: 41, Issue:1

    Topics: Angiography; Animals; Atrial Function; Blood Flow Velocity; Blood Pressure; Cats; Heart Atria; Hyper

1991
[Correction of pulmonary hypertension in heart surgery patients during the immediate postoperative period].
    Kardiologiia, 1989, Volume: 29, Issue:12

    Topics: Aminophylline; Delayed-Action Preparations; Hemodynamics; Humans; Hypertension, Pulmonary; Mitral Va

1989
[Antiserotonin action of several pharmacological substances on the vessels of the lungs and bronchi].
    Kardiologiia, 1969, Volume: 9, Issue:6

    Topics: Aminophylline; Analgesics; Animals; Atropine; Blood Pressure; Bronchial Spasm; Epinephrine; Fibrinol

1969
[Comparative evaluation of hypotensive effect of certain drugs in pulmonary hypertension in patients with pulmonary heart disease].
    Zhurnal eksperimental'noi i klinicheskoi meditsiny, 1974, Volume: 14, Issue:6

    Topics: Antihypertensive Agents; Atropine; Drug Evaluation; Humans; Hypertension, Pulmonary; Papaverine; Par

1974