papaverine has been researched along with Hypersensitivity in 3 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Hypersensitivity: Altered reactivity to an antigen, which can result in pathologic reactions upon subsequent exposure to that particular antigen.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Weishaar, RE | 1 |
| Cain, MH | 1 |
| Bristol, JA | 1 |
| FRANK, DE | 1 |
| Tateson, JE | 1 |
| Trist, DG | 1 |
1 review available for papaverine and Hypersensitivity
| Article | Year |
|---|---|
A new generation of phosphodiesterase inhibitors: multiple molecular forms of phosphodiesterase and the potential for drug selectivity.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 3',5'-Cyclic-GMP Phosphodiesterases; Animals; Blood Platelets; | 1985 |
2 other studies available for papaverine and Hypersensitivity
| Article | Year |
|---|---|
The use of papaverine hydrochloride in the prevention of anaphylactic shock in guinea pigs.
Topics: Anaphylaxis; Animals; Guinea Pigs; Humans; Hypersensitivity; Immune System Diseases; Immunity; Papav | 1946 |
Inhibition of adenosine-3',5'-cyclic monophosphate phosphodiesterase by potential antiallergic compounds.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Animals; Cattle; Cromolyn Sodium; Dose-Response Relationship, D | 1976 |