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papaverine and Heroin Abuse

papaverine has been researched along with Heroin Abuse in 2 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Research Excerpts

ExcerptRelevanceReference
"Papaverine has been proposed as an alternative heroin biomarker."1.51Using Papaverine and Its Metabolites, 6-Desmethyl Papaverine and 4',6-Didesmethyl Papaverine as Biomarkers to Improve the Detection Time of Heroin Use. ( Goldfine, BL; Korzun, WJ; Nanco, CR; Pierce, KL; Poklis, JL; Wolf, CE, 2019)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's1 (50.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Wolf, CE1
Pierce, KL1
Goldfine, BL1
Nanco, CR1
Poklis, JL1
Korzun, WJ1
Bogusz, MJ1
Maier, RD1
Erkens, M1
Kohls, U1

Other Studies

2 other studies available for papaverine and Heroin Abuse

ArticleYear
Using Papaverine and Its Metabolites, 6-Desmethyl Papaverine and 4',6-Didesmethyl Papaverine as Biomarkers to Improve the Detection Time of Heroin Use.
    Journal of analytical toxicology, 2019, Sep-10, Volume: 43, Issue:8

    Topics: Biomarkers; Chromatography, High Pressure Liquid; Heroin Dependence; Humans; Limit of Detection; Pap

2019
Detection of non-prescription heroin markers in urine with liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.
    Journal of analytical toxicology, 2001, Volume: 25, Issue:6

    Topics: Adult; Biomarkers; Chromatography, Liquid; Codeine; Drug Prescriptions; Heroin; Heroin Dependence; H

2001
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