papaverine and Heroin Abuse
papaverine has been researched along with Heroin Abuse in 2 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Papaverine has been proposed as an alternative heroin biomarker." | 1.51 | Using Papaverine and Its Metabolites, 6-Desmethyl Papaverine and 4',6-Didesmethyl Papaverine as Biomarkers to Improve the Detection Time of Heroin Use. ( Goldfine, BL; Korzun, WJ; Nanco, CR; Pierce, KL; Poklis, JL; Wolf, CE, 2019) |
Research
Studies (2)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 1 (50.00) | 29.6817 |
2010's | 1 (50.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Wolf, CE | 1 |
Pierce, KL | 1 |
Goldfine, BL | 1 |
Nanco, CR | 1 |
Poklis, JL | 1 |
Korzun, WJ | 1 |
Bogusz, MJ | 1 |
Maier, RD | 1 |
Erkens, M | 1 |
Kohls, U | 1 |
Other Studies
2 other studies available for papaverine and Heroin Abuse
Article | Year |
---|---|
Using Papaverine and Its Metabolites, 6-Desmethyl Papaverine and 4',6-Didesmethyl Papaverine as Biomarkers to Improve the Detection Time of Heroin Use.
Topics: Biomarkers; Chromatography, High Pressure Liquid; Heroin Dependence; Humans; Limit of Detection; Pap | 2019 |
Detection of non-prescription heroin markers in urine with liquid chromatography-atmospheric pressure chemical ionization mass spectrometry.
Topics: Adult; Biomarkers; Chromatography, Liquid; Codeine; Drug Prescriptions; Heroin; Heroin Dependence; H | 2001 |