papaverine has been researched along with Hemophilia A in 1 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Hemophilia A: The classic hemophilia resulting from a deficiency of factor VIII. It is an inherited disorder of blood coagulation characterized by a permanent tendency to hemorrhage.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Clinical studies of gene therapy for hemophilia B revealed the limitations of the intramuscular route, compelling an aggressive approach to the study of scale-independent circulatory means of vector delivery." | 1.37 | Gene transfer to muscle from the isolated regional circulation. ( Bridges, CR; Malik, A; Mead, A; Petrov, M; Stedman, HH, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Petrov, M | 1 |
| Malik, A | 1 |
| Mead, A | 1 |
| Bridges, CR | 1 |
| Stedman, HH | 1 |
1 other study available for papaverine and Hemophilia A
| Article | Year |
|---|---|
Gene transfer to muscle from the isolated regional circulation.
Topics: Animals; Blood Pressure; Capillaries; Capillary Permeability; Dependovirus; Disease Models, Animal; | 2011 |