papaverine has been researched along with Hearing Loss, Sensorineural in 3 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Hearing Loss, Sensorineural: Hearing loss resulting from damage to the COCHLEA and the sensorineural elements which lie internally beyond the oval and round windows. These elements include the AUDITORY NERVE and its connections in the BRAINSTEM.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Papaverine hydrochloride is a direct-acting vasodilator used to manage vasospasm during various neurosurgical operations." | 1.35 | Adverse effects of topical papaverine on auditory nerve function. ( Asher, AL; Chadwick, GM; Pollard, RJ; Van Der Veer, CA, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Chadwick, GM | 1 |
| Asher, AL | 1 |
| Van Der Veer, CA | 1 |
| Pollard, RJ | 1 |
| Byl, FM | 1 |
| Umemura, K | 1 |
| Takiguchi, Y | 1 |
| Nakashima, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Predictive Factors for Recovery in Idiopathic Sensory Neural Hearing Loss[NCT05112354] | Phase 2 | 40 participants (Actual) | Interventional | 2019-12-01 | Completed | ||
| Cochlear Implantation in Single Sided Deafness and Asymmetrical Hearing Loss: a Cost/Utility Study.[NCT02204618] | 160 participants (Actual) | Interventional | 2014-10-31 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for papaverine and Hearing Loss, Sensorineural
| Article | Year |
|---|---|
Sudden hearing loss: eight years' experience and suggested prognostic table.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil | 1984 |
Sudden hearing loss: eight years' experience and suggested prognostic table.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil | 1984 |
Sudden hearing loss: eight years' experience and suggested prognostic table.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil | 1984 |
Sudden hearing loss: eight years' experience and suggested prognostic table.
Topics: Adolescent; Adrenocorticotropic Hormone; Adult; Age Factors; Aged; Blood Coagulation Disorders; Chil | 1984 |
2 other studies available for papaverine and Hearing Loss, Sensorineural
| Article | Year |
|---|---|
Adverse effects of topical papaverine on auditory nerve function.
Topics: Administration, Topical; Afferent Pathways; Aged; Aged, 80 and over; Basilar Artery; Cochlear Nerve; | 2008 |
Altered effect of arachidonic acid on inner ear blood flow in rats with streptozotocin-induced diabetes.
Topics: Animals; Arachidonic Acid; Arachidonic Acids; Audiometry, Evoked Response; Diabetes Mellitus, Experi | 1991 |