Page last updated: 2024-11-02

papaverine and HIV

papaverine has been researched along with HIV in 2 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.

Research Excerpts

ExcerptRelevanceReference
"The ability of papaverine to inhibit human immunodeficiency virus (HIV) replication in H9 cell line and in peripheral blood mononuclear cell (PBMC) culture was examined."7.67Inhibitory effect of papaverine on HIV replication in vitro. ( Bassetti, D; Bonfanti, C; Caruso, A; Luzzati, R; Manca, N; Scura, G; Turano, A, 1989)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19902 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Turano, A2
Scura, G1
Caruso, A1
Bonfanti, C1
Luzzati, R2
Bassetti, D2
Manca, N1
Di Perri, G1
Segre, G1

Other Studies

2 other studies available for papaverine and HIV

ArticleYear
Inhibitory effect of papaverine on HIV replication in vitro.
    AIDS research and human retroviruses, 1989, Volume: 5, Issue:2

    Topics: Blotting, Western; Cell Division; HIV; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Papaver

1989
Recovery of immunological cutaneous responsiveness in the acquired immune deficiency syndrome following treatment with papaverine.
    The Journal of infection, 1989, Volume: 18, Issue:3

    Topics: Acquired Immunodeficiency Syndrome; HIV; Humans; Leukocyte Count; Papaverine; Skin Tests

1989