papaverine has been researched along with HIV in 2 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
HIV: Human immunodeficiency virus. A non-taxonomic and historical term referring to any of two species, specifically HIV-1 and/or HIV-2. Prior to 1986, this was called human T-lymphotropic virus type III/lymphadenopathy-associated virus (HTLV-III/LAV). From 1986-1990, it was an official species called HIV. Since 1991, HIV was no longer considered an official species name; the two species were designated HIV-1 and HIV-2.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The ability of papaverine to inhibit human immunodeficiency virus (HIV) replication in H9 cell line and in peripheral blood mononuclear cell (PBMC) culture was examined." | 7.67 | Inhibitory effect of papaverine on HIV replication in vitro. ( Bassetti, D; Bonfanti, C; Caruso, A; Luzzati, R; Manca, N; Scura, G; Turano, A, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Turano, A | 2 |
| Scura, G | 1 |
| Caruso, A | 1 |
| Bonfanti, C | 1 |
| Luzzati, R | 2 |
| Bassetti, D | 2 |
| Manca, N | 1 |
| Di Perri, G | 1 |
| Segre, G | 1 |
2 other studies available for papaverine and HIV
| Article | Year |
|---|---|
Inhibitory effect of papaverine on HIV replication in vitro.
Topics: Blotting, Western; Cell Division; HIV; Humans; In Vitro Techniques; Leukocytes, Mononuclear; Papaver | 1989 |
Recovery of immunological cutaneous responsiveness in the acquired immune deficiency syndrome following treatment with papaverine.
Topics: Acquired Immunodeficiency Syndrome; HIV; Humans; Leukocyte Count; Papaverine; Skin Tests | 1989 |