papaverine has been researched along with Granulocytic Leukemia, Chronic in 1 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Papaverine is a benzylisoquinoline alkaloid from the plant Papaver somniferum (Opium poppy)." | 1.62 | Repositioning antispasmodic drug Papaverine for the treatment of chronic myeloid leukemia. ( Ashok, C; Coumar, MS; Dyavaiah, M; Parcha, PK; Rajasekaran, B; Sarvagalla, S; Sudharshan, SJ, 2021) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 1 (100.00) | 2.80 |
| Authors | Studies |
|---|---|
| Parcha, PK | 1 |
| Sarvagalla, S | 1 |
| Ashok, C | 1 |
| Sudharshan, SJ | 1 |
| Dyavaiah, M | 1 |
| Coumar, MS | 1 |
| Rajasekaran, B | 1 |
1 other study available for papaverine and Granulocytic Leukemia, Chronic
| Article | Year |
|---|---|
Repositioning antispasmodic drug Papaverine for the treatment of chronic myeloid leukemia.
Topics: Allosteric Site; Animals; Antineoplastic Agents, Phytogenic; Apoptosis; Binding Sites; Cell Line, Tu | 2021 |