papaverine has been researched along with Chronic Primary Open Angle Glaucoma in 2 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Moxaverine 150 mg was applied intravenously over 30 min." | 5.38 | The effects of moxaverine on ocular blood flow in patients with age-related macular degeneration or primary open angle glaucoma and in healthy control subjects. ( Garhofer, G; Lasta, M; Pemp, B; Schmetterer, L; Schmidl, D; Wolzt, M, 2012) |
| "Papaverine and zolpidem were recently shown to be protective of bioenergetic loss in cell models of optic neuropathy." | 1.46 | Rescue of cell death and inflammation of a mouse model of complex 1-mediated vision loss by repurposed drug molecules. ( Cortopassi, GA; Datta, S; McMackin, MZ; Yu, AK, 2017) |
| "Moxaverine 150 mg was applied intravenously over 30 min." | 1.38 | The effects of moxaverine on ocular blood flow in patients with age-related macular degeneration or primary open angle glaucoma and in healthy control subjects. ( Garhofer, G; Lasta, M; Pemp, B; Schmetterer, L; Schmidl, D; Wolzt, M, 2012) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yu, AK | 1 |
| Datta, S | 1 |
| McMackin, MZ | 1 |
| Cortopassi, GA | 1 |
| Pemp, B | 1 |
| Garhofer, G | 1 |
| Lasta, M | 1 |
| Schmidl, D | 1 |
| Wolzt, M | 1 |
| Schmetterer, L | 1 |
2 other studies available for papaverine and Chronic Primary Open Angle Glaucoma
| Article | Year |
|---|---|
Rescue of cell death and inflammation of a mouse model of complex 1-mediated vision loss by repurposed drug molecules.
Topics: Animals; Disease Models, Animal; DNA, Mitochondrial; Electron Transport Complex I; Glaucoma, Open-An | 2017 |
The effects of moxaverine on ocular blood flow in patients with age-related macular degeneration or primary open angle glaucoma and in healthy control subjects.
Topics: Aged; Blood Flow Velocity; Choroid; Ciliary Arteries; Female; Glaucoma, Open-Angle; Humans; Infusion | 2012 |