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papaverine and Gangrene

papaverine has been researched along with Gangrene in 15 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Gangrene: Death and putrefaction of tissue usually due to a loss of blood supply.

Research Excerpts

ExcerptRelevanceReference
" Despite cessation of heparin-dihydroergotamine and infusion of intraarterial papaverine into the right femoral artery, both lower extremities progressed to frank gangrene and amputation (above-knee on the left and below-knee on the right)."3.68St. Anthony's fire: successful reversal of ergotamine-induced peripheral vasospasm by hydrostatic dilatation. ( Baader, W; Herman, C; Johansen, K, 1990)

Research

Studies (15)

TimeframeStudies, this research(%)All Research%
pre-199014 (93.33)18.7374
1990's1 (6.67)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
McLEAN, J1
JOHNSON, AB1
TALSTAD, I1
STEIN, ID1
Boley, SJ1
Baader, W1
Herman, C1
Johansen, K1
Bliss, BP1
Reed, C1
Inlis, MJ1
Besznyák, I1
Sebestény, M1
Nemes, A1
Rényi-Vámos, F1
Ancalmo, N1
Ochsner, JL1
Mac Gowan, WA1
Holland, PD1
Browne, HI1
Byrnes, DP1
Skagseth, E1
Hall, KV1
Enloe, G1
Sylvester, M1
Morris, LE1
Barner, HB1
Kaiser, GC1
Willman, VL1
Hanlon, CR1
Bour, H1
Renoux, M1
Guy-Grand, B1
Tutin, M1
Costil, J1
Escande, C1
Smyth, EH1

Other Studies

15 other studies available for papaverine and Gangrene

ArticleYear
Gangrene following fracture treated with heparin; papaverine, and intermittent venous occlusion; report of a case; reasons for using heparin.
    Surgery, 1946, Volume: 20

    Topics: Anticoagulants; Fractures, Bone; Gangrene; Heparin; Humans; Papaverine; Vascular Diseases; Veins

1946
[Phlegmasia coerulea dolens: gangrene of venous origin].
    Tidsskrift for den Norske laegeforening : tidsskrift for praktisk medicin, ny raekke, 1963, Jun-15, Volume: 83

    Topics: Anticoagulants; Cryoglobulins; Gangrene; Humans; Leg; Papaverine; Thrombophlebitis

1963
A MEDICAL APPRAISAL OF THERAPY FOR OCCLUSIVE ARTERIAL DISEASE.
    Angiology, 1964, Volume: 15

    Topics: Arteriosclerosis Obliterans; Blood Flow Velocity; Blood Vessel Prosthesis; Blood Vessel Prosthesis I

1964
Early diagnosis of acute mesenteric ischemia.
    Hospital practice (Office ed.), 1981, Volume: 16, Issue:8

    Topics: Acute Disease; Constriction, Pathologic; Embolism; Gangrene; Humans; Intestines; Ischemia; Mesenteri

1981
St. Anthony's fire: successful reversal of ergotamine-induced peripheral vasospasm by hydrostatic dilatation.
    Annals of vascular surgery, 1990, Volume: 4, Issue:6

    Topics: Catheterization; Dihydroergotamine; Drug Combinations; Ergotism; Gangrene; Heparin; Heparin, Low-Mol

1990
Pressure, flow and peripheral resistance measurements during surgery for femoro-popliteal occlusion (preliminary observations on 21 limbs).
    Scandinavian journal of clinical and laboratory investigation. Supplementum, 1973, Volume: 128

    Topics: Aged; Angiography; Arterial Occlusive Diseases; Arteriovenous Shunt, Surgical; Blood Flow Velocity;

1973
Acute massive gangrene of tongue.
    British medical journal, 1965, Sep-04, Volume: 2, Issue:5461

    Topics: Aged; Arteriosclerosis; Carotid Artery Diseases; Diagnosis, Differential; Ganglionic Blockers; Gangr

1965
Hyperbaric oxygenation as a therapeutic method in experimental subacute and chronic peripheral circulatory disturbances.
    Acta chirurgica Academiae Scientiarum Hungaricae, 1969, Volume: 10, Issue:4

    Topics: Animals; Disease Models, Animal; Ergotamine; Ethanolamines; Gangrene; Hyperbaric Oxygenation; Ischem

1969
Peripheral ischemia secondary to ergotamine intoxication.
    Archives of surgery (Chicago, Ill. : 1960), 1974, Volume: 109, Issue:6

    Topics: Adult; Angiography; Ergotamine; Foot; Foot Diseases; Gangrene; Humans; Ischemia; Leg; Male; Migraine

1974
The local effects of intra-arterial injections of sodium tetradecyl sulphate (S.T.D) 3 per cent. An experimental study.
    The British journal of surgery, 1972, Volume: 59, Issue:2

    Topics: Angiography; Animals; Arterial Occlusive Diseases; Blood; Contrast Media; Disease Models, Animal; Do

1972
In situ vein bypass. Experiences with new vein valve strippers.
    Scandinavian journal of thoracic and cardiovascular surgery, 1973, Volume: 7, Issue:1

    Topics: Adult; Aged; Ampicillin; Anticoagulants; Arteriovenous Shunt, Surgical; Dextrans; Female; Femoral Ve

1973
Hazards of intra-arterial injection of hydroxyzine.
    Canadian Anaesthetists' Society journal, 1969, Volume: 16, Issue:5

    Topics: Adult; Amputation, Surgical; Animals; Arm; Arteries; Dexamethasone; Female; Gangrene; Humans; Hydrox

1969
Clinical documentation of hemodynamics of the disappearing pulse.
    Archives of surgery (Chicago, Ill. : 1960), 1968, Volume: 97, Issue:2

    Topics: Aged; Angiography; Blood Flow Velocity; Blood Pressure; Female; Gangrene; Hemodynamics; Humans; Inte

1968
[Horton's disease with bilateral eye involvment, cutaneous and lingual necrosis].
    La Presse medicale, 1969, Feb-08, Volume: 77, Issue:7

    Topics: Aged; Angiography; Blindness; Cortisone; Dexamethasone; Ergotamine; Female; Gangrene; Giant Cell Art

1969
Major arterial injury in closed fracture of the neck of the humerus. Report of a case.
    The Journal of bone and joint surgery. British volume, 1969, Volume: 51, Issue:3

    Topics: Aged; Amputation, Surgical; Arm; Axillary Artery; Brachial Artery; Female; Forearm; Gangrene; Humans

1969