Page last updated: 2024-11-02

papaverine and Folic Acid Deficiency

papaverine has been researched along with Folic Acid Deficiency in 1 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Folic Acid Deficiency: A nutritional condition produced by a deficiency of FOLIC ACID in the diet. Many plant and animal tissues contain folic acid, abundant in green leafy vegetables, yeast, liver, and mushrooms but destroyed by long-term cooking. Alcohol interferes with its intermediate metabolism and absorption. Folic acid deficiency may develop in long-term anticonvulsant therapy or with use of oral contraceptives. This deficiency causes anemia, macrocytic anemia, and megaloblastic anemia. It is indistinguishable from vitamin B 12 deficiency in peripheral blood and bone marrow findings, but the neurologic lesions seen in B 12 deficiency do not occur. (Merck Manual, 16th ed)

Research Excerpts

ExcerptRelevanceReference
"Hyperhomocysteinemia was induced in DDAH1 transgenic (DDAH1 Tg) mice and wild-type littermates using a high methionine/low folate (HM/LF) diet."7.76Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. ( Arning, E; Baumbach, GL; Bottiglieri, T; Cooke, JP; Dayoub, H; Faraci, FM; Kimoto, M; Lentz, SR; Lynch, CM; Murry, DJ; Rodionov, RN; Stevens, JW; Wilson, KM, 2010)
"Hyperhomocysteinemia was induced in DDAH1 transgenic (DDAH1 Tg) mice and wild-type littermates using a high methionine/low folate (HM/LF) diet."3.76Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia. ( Arning, E; Baumbach, GL; Bottiglieri, T; Cooke, JP; Dayoub, H; Faraci, FM; Kimoto, M; Lentz, SR; Lynch, CM; Murry, DJ; Rodionov, RN; Stevens, JW; Wilson, KM, 2010)

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Rodionov, RN1
Dayoub, H1
Lynch, CM1
Wilson, KM1
Stevens, JW1
Murry, DJ1
Kimoto, M1
Arning, E1
Bottiglieri, T1
Cooke, JP1
Baumbach, GL1
Faraci, FM1
Lentz, SR1

Other Studies

1 other study available for papaverine and Folic Acid Deficiency

ArticleYear
Overexpression of dimethylarginine dimethylaminohydrolase protects against cerebral vascular effects of hyperhomocysteinemia.
    Circulation research, 2010, Feb-19, Volume: 106, Issue:3

    Topics: Acetylcholine; Amidohydrolases; Animals; Arginine; Arterioles; Carotid Artery Thrombosis; Cerebral A

2010