papaverine has been researched along with Fibrosarcoma in 2 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Fibrosarcoma: A sarcoma derived from deep fibrous tissue, characterized by bundles of immature proliferating fibroblasts with variable collagen formation, which tends to invade locally and metastasize by the bloodstream. (Stedman, 25th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In a dose-response experiment the tumour and subcutaneous vascular beds seemed to be equally sensitive to noradrenaline." | 1.26 | Influence of vasoactive drugs on local tumor blood flow. ( Lilja, J; Mattsson, J; Peterson, HI, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Karlsson, L | 1 |
| Alpsten, A | 1 |
| Mattsson, J | 2 |
| Peterson, HI | 2 |
| Lilja, J | 1 |
2 other studies available for papaverine and Fibrosarcoma
| Article | Year |
|---|---|
Influence of vasoactive drugs on the intratumor distribution of blood flow and vascular volume in a transplantable rat fibrosarcoma.
Topics: Animals; Fibrosarcoma; Muscles; Neoplasm Transplantation; Norepinephrine; Papaverine; Plasma Volume; | 1983 |
Influence of vasoactive drugs on local tumor blood flow.
Topics: Animals; Blood Vessels; Dose-Response Relationship, Drug; Fibrosarcoma; Isoproterenol; Microscopy, E | 1982 |