Page last updated: 2024-11-02

papaverine and Facial Palsy

papaverine has been researched along with Facial Palsy in 3 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Research Excerpts

ExcerptRelevanceReference
"Some evidence in the literature supports the topical application of papaverine to the cochlear nerve to prevent internal auditory artery vasospasm and cochlear ischemia as a method of enhancing the ability to preserve hearing during acoustic neuroma surgery."3.74Transient facial nerve palsy after topical papaverine application during vestibular schwannoma surgery. Case report. ( Liu, JK; MacDonald, JD; Sayama, CM; Shelton, C, 2007)
"A case of loss of spontaneous and evoked facial muscle activity, and transient postoperative facial paralysis, after topical application of papaverine in the CPA during surgery for an acoustic neuroma using intraoperative cranial nerve monitoring is reported."3.70Topical papaverine and facial nerve dysfunction in cerebellopontine angle surgery. ( Digoy, GP; Eisenman, DJ; Selesnick, SH; Victor, JD, 1999)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's1 (33.33)18.2507
2000's2 (66.67)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Lang, EW1
Neugebauer, M1
Ng, K1
Fung, V1
Clouston, P1
Dorsch, NW1
Liu, JK1
Sayama, CM1
Shelton, C1
MacDonald, JD1
Eisenman, DJ1
Digoy, GP1
Victor, JD1
Selesnick, SH1

Other Studies

3 other studies available for papaverine and Facial Palsy

ArticleYear
Facial nerve palsy after intracisternal papaverine application during aneurysm surgery--case report.
    Neurologia medico-chirurgica, 2002, Volume: 42, Issue:12

    Topics: Cisterna Magna; Facial Nerve Diseases; Facial Paralysis; Female; Humans; Intracranial Aneurysm; Midd

2002
Transient facial nerve palsy after topical papaverine application during vestibular schwannoma surgery. Case report.
    Journal of neurosurgery, 2007, Volume: 107, Issue:5

    Topics: Administration, Topical; Facial Paralysis; Female; Humans; Intraoperative Complications; Middle Aged

2007
Topical papaverine and facial nerve dysfunction in cerebellopontine angle surgery.
    The American journal of otology, 1999, Volume: 20, Issue:1

    Topics: Action Potentials; Administration, Topical; Adult; Animals; Arteries; Cerebellopontine Angle; Cerebe

1999