papaverine has been researched along with Experimental Neoplasms in 19 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The effects of microwave induced hyperthermia, papaverine, and chemotherapy were evaluated in transplanted CI300 murine neuroblastoma." | 7.66 | Synergistic effect of hyperthermia, papaverine, and chemotherapy in murine neuroblastoma. ( Grosfeld, JL; Weber, TR; West, KW, 1980) |
| "The effect of papaverine on transplantable C1300 murine neuroblastoma model was evaluated." | 7.66 | A study of the effect of papaverine in neuroblastoma using the experimental C1300 murine system. ( Murphy, GP; Wajsman, Z; Williams, P, 1978) |
| "Mouse neuroblastoma cells in culture have been used as a model for the study of the mechanism by which activities of tyrosine hydroxylase (EC 1." | 7.65 | Regulation of tyrosine hydroxylase activity in cultured mouse neuroblastoma cells: elevation induced by analogs of adenosine 3':5'-cyclic monophosphate. ( Prasad, KN; Waymire, JC; Weiner, N, 1972) |
| "The effects of microwave induced hyperthermia, papaverine, and chemotherapy were evaluated in transplanted CI300 murine neuroblastoma." | 3.66 | Synergistic effect of hyperthermia, papaverine, and chemotherapy in murine neuroblastoma. ( Grosfeld, JL; Weber, TR; West, KW, 1980) |
| "Sodium butyrate and cyclic AMP-stimulating agents (prostaglandin E1, papaverine, theophylline, and RO20-1724) caused reductions in the cell number (primarily due to reduction in cell division) when added individually to human melanoma cells in culture." | 3.66 | Effect of sodium butyrate in combination with prostaglandin E1 and inhibitors of cyclic nucleotide phosphodiesterase on human amelanotic melanoma cells in culture. ( Prasad, KN; Sakamoto, A, 1978) |
| "The effect of papaverine on transplantable C1300 murine neuroblastoma model was evaluated." | 3.66 | A study of the effect of papaverine in neuroblastoma using the experimental C1300 murine system. ( Murphy, GP; Wajsman, Z; Williams, P, 1978) |
| "Mouse neuroblastoma cells in culture have been used as a model for the study of the mechanism by which activities of tyrosine hydroxylase (EC 1." | 3.65 | Regulation of tyrosine hydroxylase activity in cultured mouse neuroblastoma cells: elevation induced by analogs of adenosine 3':5'-cyclic monophosphate. ( Prasad, KN; Waymire, JC; Weiner, N, 1972) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 18 (94.74) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (5.26) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Yang, ZH | 1 |
| Liu, LB | 1 |
| Zhao, LN | 1 |
| Liu, YH | 1 |
| Xue, YX | 1 |
| Chelmicka-Schorr, E | 2 |
| Arnason, BG | 2 |
| Holshouser, SJ | 1 |
| Reynolds, CP | 1 |
| Perez-Polo, JR | 1 |
| Nakajima, F | 1 |
| Imashuku, S | 1 |
| Green, AA | 1 |
| Sportiello, MG | 1 |
| Atweh, SF | 1 |
| Anderson, DW | 1 |
| Crowle, AJ | 1 |
| West, KW | 1 |
| Weber, TR | 1 |
| Grosfeld, JL | 1 |
| Doore, BJ | 1 |
| Bashor, MM | 1 |
| Spitzer, N | 1 |
| Mawe, RC | 1 |
| Saier, MH | 1 |
| Penit, J | 1 |
| Huot, J | 1 |
| Jard, S | 1 |
| Lazo, JS | 1 |
| Ruddon, RW | 1 |
| Prasad, KN | 3 |
| Sakamoto, A | 1 |
| Nandy, K | 1 |
| Baste, C | 1 |
| Schneider, FH | 1 |
| Wajsman, Z | 1 |
| Williams, P | 1 |
| Murphy, GP | 1 |
| Sheppard, JR | 2 |
| Plagemann, PG | 1 |
| Kowal, J | 1 |
| Harano, Y | 1 |
| Gibson, DA | 1 |
| Reichlin, S | 1 |
| Vernadakis, A | 1 |
| Waymire, JC | 1 |
| Weiner, N | 1 |
| Knysh, IT | 1 |
| Berezovskiĭ, VA | 1 |
| Mosienko, VS | 1 |
| Bulakh, AD | 1 |
19 other studies available for papaverine and Experimental Neoplasms
| Article | Year |
|---|---|
Permeability of the blood-tumor barrier is enhanced by combining vascular endothelial growth factor with papaverine.
Topics: Animals; Blotting, Western; Brain Neoplasms; Capillary Permeability; Cell Line, Tumor; Enzyme-Linked | 2014 |
C-6 glioma growth in rats: suppression with a beta-adrenergic agonist and a phosphodiesterase inhibitor.
Topics: Animals; Brain Neoplasms; Cell Line; Cyclic AMP; Drug Therapy, Combination; Glioma; Humans; Isoprote | 1980 |
Induction of neurite outgrowth in the IMR-32 human neuroblastoma cell line by nerve growth factor.
Topics: Animals; Axons; Bucladesine; Cell Differentiation; Cell Line; Culture Media; Glioma; Humans; Male; M | 1981 |
Characterization and activation of cyclic adenosine 3':5'-monophosphate-dependent protein kinase in C1300 murine neuroblastoma clones growing in vivo.
Topics: Animals; Carrier Proteins; Clone Cells; Cyclic AMP; Cyclic AMP Receptor Protein; Enzyme Activation; | 1982 |
Response of C-6 glioma to isoproterenol and papaverine in vivo depends on beta-adrenergic receptor density.
Topics: Animals; Cells, Cultured; Glioma; In Vitro Techniques; Isoproterenol; Neoplasm Transplantation; Neop | 1984 |
Regression and differentiation of neuroblastoma tumors in mice treated with differentiating agents--prostaglandin E1 and a phosphodiesterase inhibitor, RO 20-1724.
Topics: 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Alprostadil; Animals; Cell Differentiation; Drug The | 1982 |
Synergistic effect of hyperthermia, papaverine, and chemotherapy in murine neuroblastoma.
Topics: Animals; Cyclophosphamide; Disease Models, Animal; Hyperthermia, Induced; Male; Mice; Microwaves; Ne | 1980 |
Regulation of adenosine 3' :5'-monophosphate efflux from rat glioma cells in culture*.
Topics: Animals; Biological Transport; Carbonyl Cyanide p-Trifluoromethoxyphenylhydrazone; Cell Membrane; Ce | 1975 |
Neuroblastoma cell adenylate cyclase: direct activation by adenosine and prostaglandins.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; Adenine; Adenosine; Adenylyl Cyclases; Cell Line; Cyclic GMP; D | 1976 |
Neurite extension and malignancy of neuroblastoma cells after treatment with prostaglandin E1 and papaverine.
Topics: Animals; Cell Differentiation; Cell Division; Cells, Cultured; Cyclic AMP; Cyclic GMP; Male; Mice; M | 1977 |
Effect of sodium butyrate in combination with prostaglandin E1 and inhibitors of cyclic nucleotide phosphodiesterase on human amelanotic melanoma cells in culture.
Topics: 3',5'-Cyclic-AMP Phosphodiesterases; 4-(3-Butoxy-4-methoxybenzyl)-2-imidazolidinone; Butyrates; Cell | 1978 |
Further studies on the effects of centrophenoxine on lipofuscin pigment in neuroblastoma cells in culture: an electron microscopic study.
Topics: Aging; Animals; Cells, Cultured; Glycolates; Lipofuscin; Meclofenoxate; Mice; Neoplasms, Experimenta | 1978 |
A study of the effect of papaverine in neuroblastoma using the experimental C1300 murine system.
Topics: Animals; Drug Evaluation, Preclinical; Mice; Mice, Inbred A; Neoplasm Metastasis; Neoplasms, Experim | 1978 |
Inhibitors of cyclic-nucleotide phosphodiesterase induce morphological differentiation of mouse neuroblastoma cell culture.
Topics: Animals; Axons; Benzyl Compounds; Cell Count; Cell Differentiation; Cells, Cultured; Culture Media; | 1972 |
Competitive inhibition of the transport of nucleosides, hypoxanthine, choline and deoxyglucose by theophylline, papaverine and prostaglandins.
Topics: Animals; Binding, Competitive; Biological Transport, Active; Carcinoma, Hepatocellular; Cells, Cultu | 1974 |
Adrenal cells in tissue culture. The effect of papaverine and amytal on steroidogenesis, respiration and replication.
Topics: Adrenal Cortex; Adrenal Cortex Neoplasms; Adrenal Gland Neoplasms; Adrenal Glands; Adrenocorticotrop | 1974 |
(3H)Uridine uptake and incorporation into RNA in the C-6 glial cells following dibutyryl cyclic AMP treatment.
Topics: Animals; Astrocytoma; Brain Neoplasms; Bucladesine; Cell Line; DNA, Neoplasm; Models, Biological; Ne | 1974 |
Regulation of tyrosine hydroxylase activity in cultured mouse neuroblastoma cells: elevation induced by analogs of adenosine 3':5'-cyclic monophosphate.
Topics: Animals; Butyrates; Carbon Isotopes; Cell Differentiation; Clone Cells; Cyclic AMP; Kinetics; Method | 1972 |
[Effect of vasodilator agents and hyperthermia on oxygen tension in normal and neoplastic tissues].
Topics: Acetylcholine; Animals; Benz(a)Anthracenes; Histamine; Hot Temperature; Humans; Muscles; Neoplasm Tr | 1971 |