papaverine has been researched along with Dysmenorrhea in 8 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Dysmenorrhea: Painful menstruation.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Ibuprofen was more efficient and the effect was faster, than drotaverine in relieving pain in dysmenorrhoea." | 2.73 | [Comparative efficacy and tolerability of drotaverine 80 mg and ibuprofen 400 mg in patients with primary dysmenorrhoea--protocol DOROTA]. ( Debska, M; Debski, R; Mazurek, M; Niemiec, T, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 6 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Pareek, A | 1 |
| Chandurkar, NB | 1 |
| Patil, RT | 1 |
| Agrawal, SN | 1 |
| Uday, RB | 1 |
| Tambe, SG | 1 |
| DE LA FUENTE, H | 1 |
| BALDINI, BE | 1 |
| ALT, L | 1 |
| MAKLARI, L | 1 |
| WHITE, JR | 1 |
| Debski, R | 1 |
| Niemiec, T | 1 |
| Mazurek, M | 1 |
| Debska, M | 1 |
| Frenzel, KH | 1 |
| Schaepman-van Geuns, EJ | 1 |
| Götz, HG | 1 |
1 review available for papaverine and Dysmenorrhea
| Article | Year |
|---|---|
[Anti-dysmenorrhea drugs. 17].
Topics: Aminopyrine; Amphetamine; Analgesics; Aspirin; Atropa belladonna; Codeine; Dysmenorrhea; Ergot Alkal | 1967 |
2 trials available for papaverine and Dysmenorrhea
| Article | Year |
|---|---|
Efficacy and safety of aceclofenac and drotaverine fixed-dose combination in the treatment of primary dysmenorrhoea: a double-blind, double-dummy, randomized comparative study with aceclofenac.
Topics: Adolescent; Adult; Analgesics; Cyclooxygenase Inhibitors; Diclofenac; Double-Blind Method; Drug Comb | 2010 |
[Comparative efficacy and tolerability of drotaverine 80 mg and ibuprofen 400 mg in patients with primary dysmenorrhoea--protocol DOROTA].
Topics: Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Dose-Response Relationship, Drug; Double | 2007 |
5 other studies available for papaverine and Dysmenorrhea
| Article | Year |
|---|---|
[Spastic algomenorrhea. Its treatment with a synthetic spasmolytic].
Topics: Dysmenorrhea; Female; Humans; Muscle Spasticity; Papaverine; Parasympatholytics | 1963 |
EXPERIENCE OBTAINED WITH A NEW SPASMOLYTIC DRUG (NO-SPA).
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Cholelithiasis; Colic; Colitis; Duodenal Ulcer; | 1963 |
DYSMENORRHEA: TREATMENT WITH PAPAVERINE-DOUBLE BLIND STUDY.
Topics: Biomedical Research; Black People; Double-Blind Method; Drug Therapy; Dysmenorrhea; Female; Humans; | 1964 |
[Treatment of dysmenorrhea with Spasmo-Gentil].
Topics: Administration, Oral; Adult; Analgesics; Caffeine; Codeine; Drug Combinations; Dysmenorrhea; Female; | 1975 |
[Dysmenorrhoe].
Topics: Adolescent; Adult; Atropa belladonna; Contraceptives, Oral; Dysmenorrhea; Estrogens; Female; Humans; | 1975 |