papaverine has been researched along with Dyskinesia, Drug-Induced in 3 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Dyskinesia, Drug-Induced: Abnormal movements, including HYPERKINESIS; HYPOKINESIA; TREMOR; and DYSTONIA, associated with the use of certain medications or drugs. Muscles of the face, trunk, neck, and extremities are most commonly affected. Tardive dyskinesia refers to abnormal hyperkinetic movements of the muscles of the face, tongue, and neck associated with the use of neuroleptic agents (see ANTIPSYCHOTIC AGENTS). (Adams et al., Principles of Neurology, 6th ed, p1199)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Papaverine was given in slow-release capsules at 150 mg BID for one week followed by 300 mg BID for five weeks." | 2.65 | The effects of papaverine in tardive dyskinesia. ( Cole, JO; Gardos, G; Granacher, RP; Sniffin, C, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kobayashi, RM | 1 |
| Simpson, GM | 1 |
| Lee, JH | 1 |
| Zoubok, B | 1 |
| Gardos, G | 2 |
| Granacher, RP | 1 |
| Cole, JO | 1 |
| Sniffin, C | 1 |
1 trial available for papaverine and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
The effects of papaverine in tardive dyskinesia.
Topics: Adult; Aged; Aged, 80 and over; Dyskinesia, Drug-Induced; Female; Humans; Male; Middle Aged; Papaver | 1979 |
2 other studies available for papaverine and Dyskinesia, Drug-Induced
| Article | Year |
|---|---|
Drug therapy of tardive dyskinesia.
Topics: Age Factors; Antipsychotic Agents; Brain; Dopamine; Dyskinesia, Drug-Induced; Haloperidol; Humans; L | 1977 |
A rating scale for tardive dyskinesia.
Topics: Dyskinesia, Drug-Induced; Humans; Papaverine | 1979 |