papaverine has been researched along with Diabetic Neuropathies in 5 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Diabetic Neuropathies: Peripheral, autonomic, and cranial nerve disorders that are associated with DIABETES MELLITUS. These conditions usually result from diabetic microvascular injury involving small blood vessels that supply nerves (VASA NERVORUM). Relatively common conditions which may be associated with diabetic neuropathy include third nerve palsy (see OCULOMOTOR NERVE DISEASES); MONONEUROPATHY; mononeuropathy multiplex; diabetic amyotrophy; a painful POLYNEUROPATHY; autonomic neuropathy; and thoracoabdominal neuropathy. (From Adams et al., Principles of Neurology, 6th ed, p1325)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Only one patient had non-organic impotence." | 2.67 | Impotence in diabetes: aetiology, implications for treatment and preferred vacuum device. ( Close, CF; Hardisty, CA; Moore, KT; Moriarty, KT; Ryder, RE, 1992) |
| "Treatment with papaverine injections is generally inexpensive and effective to overcome the multifactorial causes of erectile dysfunction in this population." | 1.29 | Aetiopathogenesis and management of impotence in diabetic males: four years experience from a combined clinic. ( Boulton, AJ; Chen, TF; Payne, S; Veves, A; Webster, L, 1995) |
| "Diabetic microangiopathy is regarded as the most important pathogenic factor." | 1.27 | [Disorders of erectile potency in diabetes mellitus]. ( Floth, A; Holzmann, RM; Schramek, P, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (20.00) | 18.7374 |
| 1990's | 4 (80.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Veves, A | 1 |
| Webster, L | 1 |
| Chen, TF | 1 |
| Payne, S | 1 |
| Boulton, AJ | 1 |
| Takanami, M | 1 |
| Nagao, K | 1 |
| Ishii, N | 2 |
| Miura, K | 1 |
| Shirai, M | 2 |
| Ryder, RE | 1 |
| Close, CF | 1 |
| Moriarty, KT | 1 |
| Moore, KT | 1 |
| Hardisty, CA | 1 |
| Schramek, P | 1 |
| Holzmann, RM | 1 |
| Floth, A | 1 |
1 trial available for papaverine and Diabetic Neuropathies
| Article | Year |
|---|---|
Impotence in diabetes: aetiology, implications for treatment and preferred vacuum device.
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Erec | 1992 |
4 other studies available for papaverine and Diabetic Neuropathies
| Article | Year |
|---|---|
Aetiopathogenesis and management of impotence in diabetic males: four years experience from a combined clinic.
Topics: Adult; Aged; Algorithms; Counseling; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus | 1995 |
Is diabetic neuropathy responsible for diabetic impotence?
Topics: Algorithms; Alprostadil; Diabetic Neuropathies; Diagnosis, Differential; Erectile Dysfunction; Human | 1997 |
[Diabetic impotence].
Topics: Alprostadil; Diabetes Complications; Diabetic Angiopathies; Diabetic Neuropathies; Diagnosis, Differ | 1991 |
[Disorders of erectile potency in diabetes mellitus].
Topics: Aged; Alprostadil; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diab | 1988 |