papaverine has been researched along with Diabetes Mellitus, Adult-Onset in 9 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Only one patient had non-organic impotence." | 2.67 | Impotence in diabetes: aetiology, implications for treatment and preferred vacuum device. ( Close, CF; Hardisty, CA; Moore, KT; Moriarty, KT; Ryder, RE, 1992) |
| "Treatment with papaverine injections is generally inexpensive and effective to overcome the multifactorial causes of erectile dysfunction in this population." | 1.29 | Aetiopathogenesis and management of impotence in diabetic males: four years experience from a combined clinic. ( Boulton, AJ; Chen, TF; Payne, S; Veves, A; Webster, L, 1995) |
| "The treatment of impotence in diabetic men with vacuum tumescence therapy was studied in a specialist clinic." | 1.28 | The management of impotence in diabetic men by vacuum tumescence therapy. ( Bentley, S; Cooksey, G; Hearnshaw, JR; Jehu, D; Osborn, DE; Price, DE, 1991) |
| "Diabetic microangiopathy is regarded as the most important pathogenic factor." | 1.27 | [Disorders of erectile potency in diabetes mellitus]. ( Floth, A; Holzmann, RM; Schramek, P, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (11.11) | 18.7374 |
| 1990's | 5 (55.56) | 18.2507 |
| 2000's | 1 (11.11) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 1 (11.11) | 2.80 |
| Authors | Studies |
|---|---|
| Huang, TL | 1 |
| Mayence, A | 1 |
| Vanden Eynde, JJ | 1 |
| Grigolon, G | 1 |
| Araldi, E | 1 |
| Erni, R | 1 |
| Wu, JY | 1 |
| Thomas, C | 1 |
| La Fortezza, M | 1 |
| Laube, B | 1 |
| Pöhlmann, D | 1 |
| Stoffel, M | 1 |
| Zarse, K | 1 |
| Carreira, EM | 1 |
| Ristow, M | 1 |
| Fischer, F | 1 |
| Kahvecioğlu, N | 1 |
| Kurt, A | 1 |
| Ipek, A | 1 |
| Yazicioğlu, KR | 1 |
| Akbulut, Z | 1 |
| Veves, A | 1 |
| Webster, L | 1 |
| Chen, TF | 1 |
| Payne, S | 1 |
| Boulton, AJ | 1 |
| Nitenberg, A | 1 |
| Paycha, F | 1 |
| Ledoux, S | 1 |
| Sachs, R | 1 |
| Attali, JR | 1 |
| Valensi, P | 1 |
| Ryder, RE | 1 |
| Close, CF | 1 |
| Moriarty, KT | 1 |
| Moore, KT | 1 |
| Hardisty, CA | 1 |
| Parfitt, VJ | 1 |
| Wong, R | 1 |
| Dobbie, A | 1 |
| Hartog, M | 1 |
| Gingell, JC | 1 |
| Price, DE | 1 |
| Cooksey, G | 1 |
| Jehu, D | 1 |
| Bentley, S | 1 |
| Hearnshaw, JR | 1 |
| Osborn, DE | 1 |
| Schramek, P | 1 |
| Holzmann, RM | 1 |
| Floth, A | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Influence of Liraglutide on Diastolic Cardiac Function and Myocardial Perfusion as Determined by Magnetic Resonance Imaging in Patients With Type 2 Diabetes: a Double-blind Randomized Parallel-group Trial[NCT02655770] | Phase 4 | 40 participants (Actual) | Interventional | 2016-02-29 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for papaverine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Some non-conventional biomolecular targets for diamidines. A short survey.
Topics: Amidines; Animals; Diabetes Mellitus, Type 2; DNA; Enzymes; Humans; Hypertension; Ion Channels; Myot | 2014 |
1 trial available for papaverine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Impotence in diabetes: aetiology, implications for treatment and preferred vacuum device.
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Neuropathies; Erec | 1992 |
7 other studies available for papaverine and Diabetes Mellitus, Adult-Onset
| Article | Year |
|---|---|
Grainyhead 1 acts as a drug-inducible conserved transcriptional regulator linked to insulin signaling and lifespan.
Topics: Animals; Animals, Genetically Modified; Blood Glucose; Caenorhabditis elegans; Caenorhabditis elegan | 2022 |
Predictive value of cavernosal peak systolic velocity in the flaccid penis.
Topics: Adult; Aged; Arteries; Blood Flow Velocity; Diabetes Mellitus, Type 2; Diagnosis, Differential; Erec | 2009 |
Aetiopathogenesis and management of impotence in diabetic males: four years experience from a combined clinic.
Topics: Adult; Aged; Algorithms; Counseling; Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus | 1995 |
Coronary artery responses to physiological stimuli are improved by deferoxamine but not by L-arginine in non-insulin-dependent diabetic patients with angiographically normal coronary arteries and no other risk factors.
Topics: Adult; Antidotes; Arginine; Cold Temperature; Coronary Angiography; Coronary Vessels; Deferoxamine; | 1998 |
Staphylococcal septicaemia complicating intracavernosal autoinjection therapy for impotence in a man with diabetes.
Topics: Bacteremia; Diabetes Mellitus, Type 2; Drug Therapy, Combination; Erectile Dysfunction; Floxacillin; | 1992 |
The management of impotence in diabetic men by vacuum tumescence therapy.
Topics: Diabetes Mellitus; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Erectile Dysfunction; Human | 1991 |
[Disorders of erectile potency in diabetes mellitus].
Topics: Aged; Alprostadil; Diabetes Mellitus, Type 1; Diabetes Mellitus, Type 2; Diabetic Angiopathies; Diab | 1988 |