papaverine has been researched along with Dermatitis, Atopic in 5 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Dermatitis, Atopic: A chronic inflammatory genetically determined disease of the skin marked by increased ability to form reagin (IgE), with increased susceptibility to allergic rhinitis and asthma, and hereditary disposition to a lowered threshold for pruritus. It is manifested by lichenification, excoriation, and crusting, mainly on the flexural surfaces of the elbow and knee. In infants it is known as infantile eczema.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Papaverine has been reported, largely on the basis of clinical experience, to reduce the severity of pruritus associated with atopic dermatitis." | 9.06 | Failure of papaverine to reduce pruritus in atopic dermatitis: a double-blind, placebo-controlled cross-over study. ( Berth-Jones, J; Graham-Brown, RA, 1990) |
| "Papaverine has been reported, largely on the basis of clinical experience, to reduce the severity of pruritus associated with atopic dermatitis." | 5.06 | Failure of papaverine to reduce pruritus in atopic dermatitis: a double-blind, placebo-controlled cross-over study. ( Berth-Jones, J; Graham-Brown, RA, 1990) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (40.00) | 18.7374 |
| 1990's | 3 (60.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Shupack, J | 1 |
| Stiller, M | 1 |
| Meola, T | 1 |
| Orbuch, P | 1 |
| Berth-Jones, J | 1 |
| Graham-Brown, RA | 1 |
| Hoting, E | 1 |
| Reiss, J | 1 |
| Schulz, KH | 1 |
| Ayres, S | 1 |
| Baer, RL | 1 |
3 trials available for papaverine and Dermatitis, Atopic
| Article | Year |
|---|---|
Papaverine hydrochloride in the treatment of atopic dermatitis: a double-blind, placebo-controlled crossover clinical trial to reassess safety and efficacy.
Topics: Administration, Oral; Adolescent; Adult; Dermatitis, Atopic; Double-Blind Method; Female; Humans; Ma | 1991 |
Failure of papaverine to reduce pruritus in atopic dermatitis: a double-blind, placebo-controlled cross-over study.
Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Dermatitis, Atopic; Double-Blind Method; Female; H | 1990 |
[Papaverin--effective in therapy of pruritus of atopic dermatitis?].
Topics: Administration, Oral; Dermatitis, Atopic; Dose-Response Relationship, Drug; Humans; Intradermal Test | 1990 |
2 other studies available for papaverine and Dermatitis, Atopic
| Article | Year |
|---|---|
Atopic dermatitis: papaverine therapy versus the Scholtz regimen.
Topics: Administration, Oral; Dermatitis, Atopic; Drug Combinations; Drug Therapy, Combination; Fatty Alcoho | 1986 |
Papaverine therapy in atopic dermatitis.
Topics: Adrenal Cortex Hormones; Dermatitis, Atopic; Humans; Papaverine; Phosphodiesterase Inhibitors | 1985 |