papaverine has been researched along with Deafness, Sudden in 8 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Deafness, Sudden: Complete sensorineural hearing loss which develops suddenly over a period of hours or a few days.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In patients with sudden deafness, the oxygen supply to the vestibular tissues is significantly reduced but the response to carbogen is still possible." | 2.65 | Management of sudden deafness. ( Fisch, U, 1983) |
| "A total of 55 patients with sudden deafness have been treated in a prospective randomized study by inhalation with 95% O2 and 5% CO2 or intravenous infusion with papaverin and dextran." | 2.65 | [Therapy of sudden deafness with O2/CO2 inhalation (author's transl)]. ( Giger, HL, 1979) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (37.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 3 (37.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Bittar, RS | 1 |
| Oiticica, J | 1 |
| Zerati, FE | 1 |
| Bento, RF | 1 |
| Ben-David, J | 1 |
| Luntz, M | 1 |
| Magamsa, I | 1 |
| Fradis, M | 1 |
| Sabo, E | 1 |
| Podoshin, L | 1 |
| Kiriş, M | 1 |
| Cankaya, H | 1 |
| Içli, M | 1 |
| Kutluhan, A | 1 |
| Fisch, U | 1 |
| Gu, Z | 1 |
| Tong, L | 1 |
| Sun, K | 1 |
| Cheng, Z | 1 |
| Meyerhoff, WL | 1 |
| Giger, HL | 1 |
2 trials available for papaverine and Deafness, Sudden
| Article | Year |
|---|---|
Management of sudden deafness.
Topics: Animals; Blood Pressure; Carbon Dioxide; Cats; Ear, Inner; Hearing Loss, Sudden; Humans; Injections, | 1983 |
[Therapy of sudden deafness with O2/CO2 inhalation (author's transl)].
Topics: Carbon Dioxide; Dextrans; Hearing; Hearing Loss, Sudden; Humans; Injections, Intravenous; Oxygen; Pa | 1979 |
6 other studies available for papaverine and Deafness, Sudden
| Article | Year |
|---|---|
Sudden hearing loss: a ten-year outpatient experience.
Topics: Acyclovir; Adolescent; Adult; Aged; Aged, 80 and over; Ambulatory Care; Anti-Inflammatory Agents; Au | 2009 |
Tinnitus as a prognostic sign in idiopathic sudden sensorineural hearing loss.
Topics: Adult; Aged; Audiometry; Auditory Threshold; Dextrans; Female; Glucocorticoids; Hearing Loss, Sudden | 2001 |
Retrospective analysis of our cases with sudden hearing loss.
Topics: Adolescent; Adult; Aged; Anti-Anxiety Agents; Anticoagulants; Audiometry, Pure-Tone; Auditory Thresh | 2003 |
[Sudden deafness: stepwise regression analysis on the correlation factors with prognosis].
Topics: Adult; Age Factors; Auditory Threshold; Drug Therapy, Combination; Female; Hearing Loss, Sudden; Hum | 1997 |
[Observation on large doses of urokinase in treatment of sudden deafness].
Topics: Adolescent; Adult; Aged; Child; Female; Hearing Loss, Sudden; Humans; Male; Middle Aged; Papaverine; | 1998 |
The management of sudden deafness.
Topics: Adrenocorticotropic Hormone; Dextrans; Hearing Loss, Sudden; Heparin; Humans; Papaverine | 1979 |