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papaverine and Cytomegalovirus

papaverine has been researched along with Cytomegalovirus in 4 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Cytomegalovirus: A genus of the family HERPESVIRIDAE, subfamily BETAHERPESVIRINAE, infecting the salivary glands, liver, spleen, lungs, eyes, and other organs, in which they produce characteristically enlarged cells with intranuclear inclusions. Infection with Cytomegalovirus is also seen as an opportunistic infection in AIDS.

Research Excerpts

ExcerptRelevanceReference
"Amiloride, an inhibitor of Na+/H+ exchange, interfered with cytomegalovirus (CMV) DNA synthesis, blocked the formation of nuclear inclusions, and reduced CMV infectious yields."7.68Amiloride inhibition of human cytomegalovirus replication. ( Albrecht, T; Cerruti-Sola, S; Fons, M; Nokta, M, 1991)
"Amiloride, an inhibitor of Na+/H+ exchange, interfered with cytomegalovirus (CMV) DNA synthesis, blocked the formation of nuclear inclusions, and reduced CMV infectious yields."3.68Amiloride inhibition of human cytomegalovirus replication. ( Albrecht, T; Cerruti-Sola, S; Fons, M; Nokta, M, 1991)
"The effect of the smooth-muscle relaxing agents, papaverine, sodium nitroprusside, and verapamil, on the replication of human cytomegalovirus (CMV) was investigated."3.67Inhibition of cytomegalovirus replication by smooth-muscle relaxing agents. ( Albrecht, T; Lee, CH; Speelman, DJ; Steinsland, OS, 1987)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's2 (50.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Albrecht, T4
Speelman, DJ2
Steinsland, OS2
Fons, M2
Nokta, M1
Cerruti-Sola, S1
Boldogh, I1
AbuBakar, S1
Deng, CZ1
Lee, CH1

Reviews

1 review available for papaverine and Cytomegalovirus

ArticleYear
Cell activation signals and the pathogenesis of human cytomegalovirus.
    Intervirology, 1990, Volume: 31, Issue:2-4

    Topics: Amiloride; Cytomegalovirus; Cytomegalovirus Infections; DNA, Viral; Humans; Papaverine; Phosphatidyl

1990

Other Studies

3 other studies available for papaverine and Cytomegalovirus

ArticleYear
Similarities between cytomegalovirus-induced cell rounding and contraction of smooth muscle cells.
    Life sciences, 1983, May-09, Volume: 32, Issue:19

    Topics: Cytomegalovirus; Cytomegalovirus Infections; Cytopathogenic Effect, Viral; Diazoxide; Fibroblasts; H

1983
Amiloride inhibition of human cytomegalovirus replication.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1991, Volume: 196, Issue:1

    Topics: Amiloride; Cytomegalovirus; DNA Replication; Dose-Response Relationship, Drug; Electrophoresis, Poly

1991
Inhibition of cytomegalovirus replication by smooth-muscle relaxing agents.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1987, Volume: 186, Issue:1

    Topics: Cytomegalovirus; Cytopathogenic Effect, Viral; Depression, Chemical; DNA Replication; Ferricyanides;

1987