papaverine has been researched along with Cough in 4 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.
| Excerpt | Relevance | Reference |
|---|---|---|
| "25 mg/kg) papaverine was able to decrease enalapril induced cough." | 7.73 | Interaction of papaverine with the enalapril-induced cough in guinea pig. ( Ebrahimi, SA; Mahmoudian, M; Rostami, P; Saghaeian-Shahri, T; Shafiei, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (75.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| ENDERS, A | 1 |
| SCHMIDT, L | 1 |
| Ebrahimi, SA | 1 |
| Saghaeian-Shahri, T | 1 |
| Shafiei, M | 1 |
| Rostami, P | 1 |
| Mahmoudian, M | 1 |
| Tardos, L | 1 |
| Erdély, I | 1 |
| Clay, TP | 1 |
| Thompson, MA | 1 |
4 other studies available for papaverine and Cough
| Article | Year |
|---|---|
[Reflex activity of the cough center and the respiratory center under the influence of papaverin hydrochloride].
Topics: Cell Respiration; Cough; Nervous System Physiological Phenomena; Papaverine; Reflex; Respiration; Re | 1958 |
Interaction of papaverine with the enalapril-induced cough in guinea pig.
Topics: Angiotensin-Converting Enzyme Inhibitors; Animals; Cough; Enalapril; Guinea Pigs; Male; Papaverine; | 2006 |
[Pharmacologic studies on the new antitussive agent, 3-(2,2-diphenylethyl)-5-(2-piperidinoethyl)-1,2,4-oxadiazole].
Topics: Animals; Antitussive Agents; Cats; Codeine; Cough; Guinea Pigs; In Vitro Techniques; Mice; Oxadiazol | 1966 |
Irritant induced cough as a model of intrapulmonary airway reactivity.
Topics: Airway Resistance; Animals; Bronchial Provocation Tests; Citrates; Citric Acid; Cough; Guinea Pigs; | 1985 |