papaverine has been researched along with Coronary Vasospasm in 13 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Coronary Vasospasm: Spasm of the large- or medium-sized coronary arteries.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Papaverine was analyzed in positive mode using an electrospray ion source." | 2.78 | Pharmacokinetics of intraluminally administered serum papaverine for spasm prophylaxis of the internal mammary artery. ( Beiras-Fernandez, A; Ferreirós, N; Kiessling, AH; Labocha, S; Moritz, A; Rastan, AJ; Romasku, D, 2013) |
| "Papaverine was also superior to milrinone in the preservation of endothelial integrity (75." | 1.39 | Vasodilatory effect and endothelial integrity in papaverine- and milrinone-treated human radial arteries. ( Guzik, T; Jasinska, M; Konstanty-Kalandyk, J; Korbut, R; Lis, GJ; Litwin, JA; Mikolajczyk, T; Nosalski, R; Piatek, J; Pyka-Fosciak, G; Rudzinski, P; Sadowski, J; Wegrzyn, P, 2013) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 4 (30.77) | 18.2507 |
| 2000's | 6 (46.15) | 29.6817 |
| 2010's | 3 (23.08) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Rudzinski, P | 1 |
| Wegrzyn, P | 1 |
| Lis, GJ | 1 |
| Piatek, J | 1 |
| Konstanty-Kalandyk, J | 1 |
| Nosalski, R | 1 |
| Mikolajczyk, T | 1 |
| Jasinska, M | 1 |
| Pyka-Fosciak, G | 1 |
| Guzik, T | 1 |
| Litwin, JA | 1 |
| Korbut, R | 1 |
| Sadowski, J | 1 |
| Kiessling, AH | 1 |
| Romasku, D | 1 |
| Beiras-Fernandez, A | 1 |
| Ferreirós, N | 1 |
| Labocha, S | 1 |
| Moritz, A | 1 |
| Rastan, AJ | 1 |
| Zhu, W | 1 |
| Liu, S | 2 |
| Zhao, J | 1 |
| Jiang, S | 1 |
| Li, B | 1 |
| Yang, H | 1 |
| Fan, C | 1 |
| Cui, W | 1 |
| Kelsall, CJ | 1 |
| Chester, AH | 1 |
| Amrani, M | 1 |
| Singer, DR | 1 |
| Tarhan, A | 1 |
| Kehlibar, T | 2 |
| Yapici, F | 1 |
| Yilmaz, M | 2 |
| Arslan, Y | 2 |
| Yapici, N | 1 |
| Ozler, A | 2 |
| Qi, XR | 1 |
| Yan, Y | 1 |
| Ma, XD | 1 |
| Li, TY | 1 |
| Nie, XY | 1 |
| Yang, BB | 1 |
| Tarhan, IA | 1 |
| Dumantepe, M | 1 |
| Berkoz, K | 1 |
| Pancaroglu, C | 1 |
| Ninomiya, Y | 1 |
| Hamasaki, S | 1 |
| Saihara, K | 1 |
| Ishida, S | 1 |
| Kataoka, T | 1 |
| Ogawa, M | 1 |
| Orihara, K | 1 |
| Oketani, N | 1 |
| Fukudome, T | 1 |
| Okui, H | 1 |
| Ichiki, T | 1 |
| Shinsato, T | 1 |
| Kubozono, T | 1 |
| Mizoguchi, E | 1 |
| Ichiki, H | 1 |
| Tei, C | 1 |
| Dregelid, E | 1 |
| Heldal, K | 1 |
| Resch, F | 1 |
| Stangeland, L | 1 |
| Breivik, K | 1 |
| Svendsen, E | 1 |
| Uydeş-Doğan, BS | 1 |
| Nebigil, M | 1 |
| Aslamaci, S | 1 |
| Onuk, E | 1 |
| Kanzik, I | 1 |
| Akar, F | 1 |
| S-Aslamaci, MD | 1 |
| Biraima, AM | 1 |
| Genoni, M | 1 |
| Winkler, MB | 1 |
| Brühlmann, W | 1 |
| Turina, MI | 1 |
| Hess, OM | 1 |
| Felder, L | 1 |
| Gaglione, A | 1 |
| Buechi, M | 1 |
| Vassalli, F | 1 |
| Jiang, Z | 1 |
| Grimm, J | 1 |
| Krayenbuehl, HP | 1 |
| Gurley, JC | 1 |
| Booth, DC | 1 |
| DeMaria, AN | 1 |
5 trials available for papaverine and Coronary Vasospasm
| Article | Year |
|---|---|
Pharmacokinetics of intraluminally administered serum papaverine for spasm prophylaxis of the internal mammary artery.
Topics: Adult; Aged; Coronary Vasospasm; Female; Humans; Internal Mammary-Coronary Artery Anastomosis; Male; | 2013 |
Role of physiological state 'normothermia' in internal thoracic artery spasm after harvesting.
Topics: Adult; Aged; Body Temperature; Coronary Vasospasm; Female; Humans; Internal Mammary-Coronary Artery | 2006 |
Normothermia is the key for the treatment of internal thoracic artery spasm.
Topics: Aged; Coronary Vasospasm; Female; Hot Temperature; Humans; Hypothermia, Induced; Male; Mammary Arter | 2007 |
Comparison of effect between nitrates and calcium channel antagonist on vascular function in patients with normal or mildly diseased coronary arteries.
Topics: Acetylcholine; Aged; Angina Pectoris; Calcium Channel Blockers; Coronary Angiography; Coronary Arter | 2008 |
Dilation of the internal mammary artery by external and intraluminal papaverine application.
Topics: Adult; Aged; Coronary Disease; Coronary Vasospasm; Female; Humans; Immersion; Injections, Intra-Arte | 1995 |
8 other studies available for papaverine and Coronary Vasospasm
| Article | Year |
|---|---|
Vasodilatory effect and endothelial integrity in papaverine- and milrinone-treated human radial arteries.
Topics: Coronary Artery Bypass; Coronary Vasospasm; Endothelium, Vascular; Female; Humans; In Vitro Techniqu | 2013 |
Highly flexible and rapidly degradable papaverine-loaded electrospun fibrous membranes for preventing vasospasm and repairing vascular tissue.
Topics: Animals; Coronary Vasospasm; Membranes, Artificial; Microscopy, Electron, Scanning; Papaverine; Rabb | 2014 |
C-type natriuretic peptide relaxes human coronary artery bypass grafts preconstricted by endothelin-1.
Topics: Acetylcholine; Coronary Artery Bypass; Coronary Vasospasm; Dose-Response Relationship, Drug; Endothe | 2005 |
Development of a local vasodilator delivery system using fibrin glue to prevent arterial graft from spasm.
Topics: Animals; Biocompatible Materials; Blood Vessel Prosthesis; Coronary Artery Bypass; Coronary Vasospas | 2007 |
The comparison of vascular reactivities of arterial and venous grafts to vasodilators: management of graft spasm.
Topics: Adult; Arteries; Coronary Artery Bypass; Coronary Vasospasm; Culture Techniques; Dose-Response Relat | 1996 |
Mesenteric ischemia after a cardiac operation: arteriosclerotic versus vasospastic etiology.
Topics: Adult; Aged; Cardiopulmonary Bypass; Catheterization; Coronary Artery Disease; Coronary Vasospasm; F | 2002 |
Coronary vasomotion and coronary flow reserve during exercise.
Topics: Adult; Coronary Angiography; Coronary Circulation; Coronary Disease; Coronary Vasospasm; Exercise; H | 1991 |
Circulatory collapse following coronary bypass surgery: multivessel and graft spasm reversed in the catheterization laboratory by intracoronary papaverine.
Topics: Adult; Angina Pectoris; Coronary Angiography; Coronary Artery Bypass; Coronary Vasospasm; Electrocar | 1990 |