papaverine has been researched along with Contracture in 6 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Contracture: Prolonged shortening of the muscle or other soft tissue around a joint, preventing movement of the joint.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The mechanisms of relaxing effect of papaverine on the phenylephrine (10(-6) M)- or the high K+ (30 mM)-induced contracture were studied on the isolated canine corpus cavernosum." | 3.68 | [Mechanisms of relaxing action of papaverine on isolated canine corpus cavernosum]. ( Yoshida, K, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (33.33) | 18.7374 |
| 1990's | 3 (50.00) | 18.2507 |
| 2000's | 1 (16.67) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Q | 1 |
| Luan, J | 1 |
| Wang, JQ | 1 |
| Tang, Y | 1 |
| Fan, JC | 1 |
| Cao, Y | 1 |
| Zhuang, Q | 1 |
| Qi, KM | 1 |
| Yoshida, K | 1 |
| Sasaki, S | 1 |
| Ueda, M | 1 |
| Kaneda, T | 1 |
| Saga, S | 1 |
| Matsuyama, M | 1 |
| Mooney, MP | 1 |
| Siegel, MI | 1 |
| Hurwitz, DJ | 1 |
| Edington, H | 1 |
| Haas, H | 2 |
6 other studies available for papaverine and Contracture
| Article | Year |
|---|---|
[Experimental study on inhibition of skin graft contraction with papaverine cream].
Topics: Animals; Contracture; Male; Papaverine; Skin Transplantation; Swine; Swine, Miniature; Wound Healing | 2004 |
[Mechanisms of relaxing action of papaverine on isolated canine corpus cavernosum].
Topics: Animals; Contracture; Dogs; Dose-Response Relationship, Drug; In Vitro Techniques; Male; Papaverine; | 1993 |
Inhibition of wound contraction by papaverine: in vitro analysis with a submucosal tissue model.
Topics: Actins; Administration, Topical; Animals; Bandages; Collagen; Contracture; Disease Models, Animal; D | 1991 |
Pharmacologic manipulation of postoperative labial wound contraction and midfacial growth in rabbits.
Topics: Analysis of Variance; Animals; Cleft Lip; Contracture; Disease Models, Animal; Electromyography; Fac | 1991 |
[Studies on coronary-active substances].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per | 1970 |
[Studies on coronary-active substances].
Topics: Animals; Anti-Arrhythmia Agents; Arrhythmias, Cardiac; Blood Circulation; Calcium; Cell Membrane Per | 1970 |