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papaverine and Complications of Diabetes Mellitus

papaverine has been researched along with Complications of Diabetes Mellitus in 20 studies

Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.

Research Excerpts

ExcerptRelevanceReference
"Thirty-three diabetic men were instructed in the use of phentolamine-papaverine injections for the treatment of erectile dysfunction over a two-year period."7.68Factors predicting efficacy of phentolamine-papaverine intracorporeal injection for treatment of erectile dysfunction in diabetic male. ( Bell, DS; Cutter, GR; Hayne, VB; Lloyd, LK, 1992)
"Thirty-three diabetic men were instructed in the use of phentolamine-papaverine injections for the treatment of erectile dysfunction over a two-year period."3.68Factors predicting efficacy of phentolamine-papaverine intracorporeal injection for treatment of erectile dysfunction in diabetic male. ( Bell, DS; Cutter, GR; Hayne, VB; Lloyd, LK, 1992)
"The usefulness of a chemical prosthesis was studied for the diagnosis and treatment of 20 patients with erectile impotence (14 due to diabetes, 2 due to pelvic surgery and 4 due to psychogenic factors) using papaverine hydrochloride and phentolamine mesilate."3.67[Diagnosis and treatment of impotence with administration of chemical prosthesis using real-time mechanical sector duplex scanner--with special reference to diabetic patients]. ( Kaneda, S; Matsuoka, K; Nakajima, Y; Shibayama, T; Suzuki, Y; Yamamoto, H, 1989)
" Real time rigidity assessment was used for the objective determination of the initial dosage and then doses were regulated in order to introduce an erection suitable for penetration and maintenance of erection for approximately 30 min."1.33Long-term treatment with intracavernosal injections in diabetic men with erectile dysfunction. ( Athanasopoulos, A; Gyftopoulos, K; Kartsanis, G; Konstantinopoulos, A; Liatsikos, E; Perimeni, PP; Perimenis, P, 2006)
" Rigiscan was used for the objective determination of the initial dosage and then doses were regulated in order to introduce an erection suitable for penetration and maintenance of erection for 30 min."1.31Diabetic impotence treated by intracavernosal injections: high treatment compliance and increasing dosage of vaso-active drugs. ( Athanasopoulos, A; Barbalias, G; Gyftopoulos, K; Perimenis, P, 2001)
"A successful impotence assessment and treatment service, including self-injection of vasoactive drugs, can be provided by a physician as part of the diabetes care service."1.28The diabetes physician and an assessment and treatment programme for male erectile impotence. ( Alexander, WD, 1990)
"We conclude that diabetic men with impotence have impairment in both the autonomic and the endothelium-dependent mechanisms that mediate the relaxation of the smooth muscle of the corpora cavernosa."1.28Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence. ( Azadzoi, K; Cohen, RA; Goldstein, I; Krane, RJ; Saenz de Tejada, I, 1989)

Research

Studies (20)

TimeframeStudies, this research(%)All Research%
pre-19907 (35.00)18.7374
1990's9 (45.00)18.2507
2000's3 (15.00)29.6817
2010's1 (5.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ismail, A1
Tabari, AM1
Alhasan, SU1
Abdullahi, A1
Kadioglu, A1
Oktar, T1
Kandirali, E1
Kendirci, M1
Sanli, O1
Ozsoy, C1
Perimenis, P2
Konstantinopoulos, A1
Perimeni, PP1
Gyftopoulos, K2
Kartsanis, G1
Liatsikos, E1
Athanasopoulos, A2
Lin, JS1
Chang, WC1
Lui, SM1
Montorsi, F1
Guazzoni, G1
Bergamaschi, F1
Zucconi, M1
Rigatti, P1
Pizzini, G1
Miani, A1
Pozza, G1
Tamura, M1
Iriguchi, H1
Miyamoto, T1
Kimura, K1
Kawanishi, Y1
Numata, A1
Yuasa, M1
Kagawa, S1
Barbalias, G1
Home, P1
Bell, DS1
Cutter, GR1
Hayne, VB1
Lloyd, LK1
Müller, SC1
el-Damanhoury, H1
Rüth, J1
Lue, TF1
Ishii, N1
Shirai, M1
Alexander, WD1
Whitehead, ED2
Klyde, BJ1
Zussman, S1
Salkin, P1
Nakajima, Y1
Shibayama, T1
Yamamoto, H1
Suzuki, Y1
Matsuoka, K1
Kaneda, S1
Wicklmayr, M1
Rett, K1
Baldermann, H1
Dietze, G1
Saenz de Tejada, I1
Goldstein, I1
Azadzoi, K1
Krane, RJ1
Cohen, RA1
Lavoisier, P1
Bernhard, VM1
Stern, FH1

Reviews

1 review available for papaverine and Complications of Diabetes Mellitus

ArticleYear
Diagnostic evaluation of impotence.
    Postgraduate medicine, 1990, Volume: 88, Issue:2

    Topics: Diabetes Complications; Erectile Dysfunction; Humans; Hyperprolactinemia; Hypogonadism; Male; Papave

1990

Trials

1 trial available for papaverine and Complications of Diabetes Mellitus

ArticleYear
Further evaluation of papaverine for peripheral vascular ischemia.
    Journal of the American Geriatrics Society, 1967, Volume: 15, Issue:4

    Topics: Aged; Clinical Trials as Topic; Diabetes Complications; Female; Humans; Intermittent Claudication; I

1967

Other Studies

18 other studies available for papaverine and Complications of Diabetes Mellitus

ArticleYear
Dynamic and morphologic evaluation of erectile dysfunction on penile doppler sonography and contrast cavernosography.
    Nigerian journal of clinical practice, 2017, Volume: 20, Issue:6

    Topics: Adult; Arteries; Contrast Media; Diabetes Complications; Humans; Hypertension; Impotence, Vasculogen

2017
Incidentally diagnosed Peyronie's disease in men presenting with erectile dysfunction.
    International journal of impotence research, 2004, Volume: 16, Issue:6

    Topics: Adult; Aged; Diabetes Complications; Erectile Dysfunction; Humans; Hypercholesterolemia; Impotence,

2004
Long-term treatment with intracavernosal injections in diabetic men with erectile dysfunction.
    Asian journal of andrology, 2006, Volume: 8, Issue:2

    Topics: Alprostadil; Diabetes Complications; Dose-Response Relationship, Drug; Drug Combinations; Erectile D

2006
The change of penile blood thromboxane B2 and prostacyclin after intracavernous injection of vasoactive drugs for the treatment of arteriogenic impotence.
    Proceedings of the National Science Council, Republic of China. Part B, Life sciences, 1994, Volume: 18, Issue:1

    Topics: 6-Ketoprostaglandin F1 alpha; Adult; Aged; Alprostadil; Diabetes Complications; Epoprostenol; Erecti

1994
Clinical reliability of multi-drug intracavernous vasoactive pharmacotherapy for diabetic impotence.
    Acta diabetologica, 1994, Volume: 31, Issue:1

    Topics: Adult; Aged; Alprostadil; Atropine; Diabetes Complications; Drug Combinations; Erectile Dysfunction;

1994
[Transition of diagnosis and treatment for impotence].
    Nihon Hinyokika Gakkai zasshi. The japanese journal of urology, 1993, Volume: 84, Issue:8

    Topics: Adolescent; Adult; Aged; Counseling; Diabetes Complications; Erectile Dysfunction; Humans; Ligation;

1993
Diabetic impotence treated by intracavernosal injections: high treatment compliance and increasing dosage of vaso-active drugs.
    European urology, 2001, Volume: 40, Issue:4

    Topics: Alprostadil; Diabetes Complications; Dose-Response Relationship, Drug; Drug Combinations; Erectile D

2001
A depressing problem.
    Diabetic medicine : a journal of the British Diabetic Association, 1992, Volume: 9, Issue:3

    Topics: Diabetes Complications; Diabetes Mellitus; Erectile Dysfunction; Humans; Male; Papaverine; Penile Pr

1992
Factors predicting efficacy of phentolamine-papaverine intracorporeal injection for treatment of erectile dysfunction in diabetic male.
    Urology, 1992, Volume: 40, Issue:1

    Topics: Age Factors; Diabetes Complications; Drug Therapy, Combination; Erectile Dysfunction; Humans; Male;

1992
Hypertension and impotence.
    European urology, 1991, Volume: 19, Issue:1

    Topics: Antihypertensive Agents; Diabetes Complications; Erectile Dysfunction; Humans; Hypertension; Male; M

1991
[Diabetic impotence].
    Nihon rinsho. Japanese journal of clinical medicine, 1991, Volume: 49 Suppl

    Topics: Alprostadil; Diabetes Complications; Diabetic Angiopathies; Diabetic Neuropathies; Diagnosis, Differ

1991
The diabetes physician and an assessment and treatment programme for male erectile impotence.
    Diabetic medicine : a journal of the British Diabetic Association, 1990, Volume: 7, Issue:6

    Topics: Adult; Aged; Counseling; Diabetes Complications; Diabetes Mellitus; Erectile Dysfunction; Humans; Ma

1990
[Diagnosis and treatment of impotence with administration of chemical prosthesis using real-time mechanical sector duplex scanner--with special reference to diabetic patients].
    Hinyokika kiyo. Acta urologica Japonica, 1989, Volume: 35, Issue:4

    Topics: Adult; Aged; Diabetes Complications; Erectile Dysfunction; Humans; Male; Middle Aged; Papaverine; Pe

1989
The kallikrein/kinin system in the pathogenesis of hypertension in diabetes mellitus.
    Diabete & metabolisme, 1989, Volume: 15, Issue:5 Pt 2

    Topics: Amino Acids; Bradykinin; Diabetes Complications; Diabetes Mellitus; Glucose; Humans; Hypertension; I

1989
Impaired neurogenic and endothelium-mediated relaxation of penile smooth muscle from diabetic men with impotence.
    The New England journal of medicine, 1989, Apr-20, Volume: 320, Issue:16

    Topics: Acetylcholine; Diabetes Complications; Diabetes Mellitus; Electric Stimulation; Endothelium, Vascula

1989
[Several techniques proposed for the differential diagnosis of diabetic impotence].
    Annales d'endocrinologie, 1988, Volume: 49, Issue:4-5

    Topics: Diabetes Complications; Diagnosis, Differential; Erectile Dysfunction; Humans; Male; Papaverine; Pen

1988
Diabetes-related impotence and its treatment in the middle-aged and elderly: Part II.
    Geriatrics, 1987, Volume: 42, Issue:8

    Topics: Aged; Counseling; Diabetes Complications; Equipment and Supplies; Erectile Dysfunction; Humans; Inje

1987
Intraoperative monitoring of femorotibial bypass grafts.
    The Surgical clinics of North America, 1974, Volume: 54, Issue:1

    Topics: Animals; Arterial Occlusive Diseases; Arteries; Blood Flow Velocity; Blood Pressure; Cattle; Diabete

1974