papaverine has been researched along with Complication, Intraoperative in 16 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Fifty-eight patients were randomized into three groups to compare papaverine's ability to prevent spasm and to treat established spasm." | 9.11 | Papaverine delivery to the internal mammary artery pedicle effectively treats spasm. ( Crawford, FA; Crumbley, AJ; Girard, DS; Kratz, JM; Sutton, JP; Williams, TH; Zellner, JL, 2004) |
| "Complications associated with intraarterial papaverine infusion occurred in two patients treated for vasospasm due to subarachnoid hemorrhage (SAH)." | 7.70 | Complications associated with intraarterial administration of papaverine for vasospasm following subarachnoid hemorrhage--two case reports. ( Hyodo, A; Kamezaki, T; Nagatomo, Y; Nose, T; Tsurushima, H, 2000) |
| "We recommend topical use of papaverine at 37 degrees C to relieve intraoperative spasm of the internal thoracic artery." | 7.69 | Effect of normothermic papaverine to relieve intraoperative spasm of the internal thoracic artery. ( Bilgen, F; Coruh, T; Ozler, A; Serbetçioğlu, A; Tarhan, IA; Yapici, MF, 1996) |
| "Papaverine was topically applied on the renal arteries resulting in vasodilation and reperfusion of the kidney." | 6.58 | Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy. ( Cadeddu, JA; Sorokin, I; Stevens, SL, 2018) |
| "Here, we describe a case of anterior communicating artery aneurysm with hydrocephalus." | 5.33 | Haemodynamic changes after intracisternal papaverine instillation during intracranial aneurysmal surgery. ( Dash, HH; Prabhakar, H; Rath, GP; Suri, A, 2006) |
| "Fifty-eight patients were randomized into three groups to compare papaverine's ability to prevent spasm and to treat established spasm." | 5.11 | Papaverine delivery to the internal mammary artery pedicle effectively treats spasm. ( Crawford, FA; Crumbley, AJ; Girard, DS; Kratz, JM; Sutton, JP; Williams, TH; Zellner, JL, 2004) |
| "Some evidence in the literature supports the topical application of papaverine to the cochlear nerve to prevent internal auditory artery vasospasm and cochlear ischemia as a method of enhancing the ability to preserve hearing during acoustic neuroma surgery." | 3.74 | Transient facial nerve palsy after topical papaverine application during vestibular schwannoma surgery. Case report. ( Liu, JK; MacDonald, JD; Sayama, CM; Shelton, C, 2007) |
| "Complications associated with intraarterial papaverine infusion occurred in two patients treated for vasospasm due to subarachnoid hemorrhage (SAH)." | 3.70 | Complications associated with intraarterial administration of papaverine for vasospasm following subarachnoid hemorrhage--two case reports. ( Hyodo, A; Kamezaki, T; Nagatomo, Y; Nose, T; Tsurushima, H, 2000) |
| "We recommend topical use of papaverine at 37 degrees C to relieve intraoperative spasm of the internal thoracic artery." | 3.69 | Effect of normothermic papaverine to relieve intraoperative spasm of the internal thoracic artery. ( Bilgen, F; Coruh, T; Ozler, A; Serbetçioğlu, A; Tarhan, IA; Yapici, MF, 1996) |
| "Two patients showed signs of elevated intracranial pressure after the procedures and also had ASrO2 readings exceeding 15%; measures to lower arterial hypertension reduced SrO2 in these patients." | 2.72 | [Behaviour of near-infrared cerebral oximetry readings during percutaneous carotid angioplasty]. ( Carrero, E; Fàbregas, N; Fontanals, J; Rodríguez, L; Salvador, L; Valero, R, 2006) |
| "Papaverine was topically applied on the renal arteries resulting in vasodilation and reperfusion of the kidney." | 2.58 | Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy. ( Cadeddu, JA; Sorokin, I; Stevens, SL, 2018) |
| "Here, we describe a case of anterior communicating artery aneurysm with hydrocephalus." | 1.33 | Haemodynamic changes after intracisternal papaverine instillation during intracranial aneurysmal surgery. ( Dash, HH; Prabhakar, H; Rath, GP; Suri, A, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (18.75) | 18.7374 |
| 1990's | 3 (18.75) | 18.2507 |
| 2000's | 7 (43.75) | 29.6817 |
| 2010's | 3 (18.75) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Sorokin, I | 1 |
| Stevens, SL | 1 |
| Cadeddu, JA | 1 |
| Zygourakis, CC | 1 |
| Vasudeva, V | 1 |
| Lai, PM | 1 |
| Kim, AH | 1 |
| Wang, H | 1 |
| Du, R | 1 |
| Ricci, JA | 1 |
| Koolen, PG | 1 |
| Shah, J | 1 |
| Tobias, AM | 1 |
| Lee, BT | 1 |
| Lin, SJ | 1 |
| Girard, DS | 1 |
| Sutton, JP | 1 |
| Williams, TH | 1 |
| Crumbley, AJ | 1 |
| Zellner, JL | 1 |
| Kratz, JM | 1 |
| Crawford, FA | 1 |
| Rath, GP | 1 |
| Prabhakar, H | 1 |
| Dash, HH | 1 |
| Suri, A | 1 |
| Rodríguez, L | 1 |
| Salvador, L | 1 |
| Valero, R | 1 |
| Carrero, E | 1 |
| Fontanals, J | 1 |
| Fàbregas, N | 1 |
| Liu, JK | 1 |
| Sayama, CM | 1 |
| Shelton, C | 1 |
| MacDonald, JD | 1 |
| Bilgen, F | 1 |
| Yapici, MF | 1 |
| Serbetçioğlu, A | 1 |
| Tarhan, IA | 1 |
| Coruh, T | 1 |
| Ozler, A | 1 |
| Walpoth, BH | 1 |
| Bosshard, A | 1 |
| Kipfer, B | 1 |
| Berdat, PA | 1 |
| Althaus, U | 1 |
| Carrel, T | 1 |
| Johnson, BL | 1 |
| Bandyk, DF | 1 |
| Back, MR | 1 |
| Avino, AJ | 1 |
| Roth, SM | 1 |
| McAtamney, D | 1 |
| McKaigue, JP | 1 |
| Tsurushima, H | 1 |
| Kamezaki, T | 1 |
| Nagatomo, Y | 1 |
| Hyodo, A | 1 |
| Nose, T | 1 |
| Cooper, GJ | 1 |
| Wilkinson, GA | 1 |
| Angelini, GD | 1 |
| Slogoff, S | 1 |
| Keats, AS | 1 |
| Hou, SM | 1 |
| Seaber, AV | 1 |
| Urbaniak, JR | 1 |
| Gearhart, JP | 1 |
| Jeffs, RD | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Pilot-Study to Evaluate the Clinical Significance of the Fluorescence Videoangiography With Indocyanine-Green in Patients With PAD, Rutherford Classification II-V, and Relation to Common Diagnostics.[NCT00876668] | 25 participants (Anticipated) | Observational | 2007-06-30 | Active, not recruiting | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
1 review available for papaverine and Complication, Intraoperative
| Article | Year |
|---|---|
Periarterial papaverine to treat renal artery vasospasm during robot-assisted laparoscopic partial nephrectomy.
Topics: Adult; Humans; Intraoperative Complications; Ischemia; Kidney; Kidney Diseases; Male; Nephrectomy; P | 2018 |
2 trials available for papaverine and Complication, Intraoperative
| Article | Year |
|---|---|
Papaverine delivery to the internal mammary artery pedicle effectively treats spasm.
Topics: Arterial Occlusive Diseases; Female; Humans; Injections; Internal Mammary-Coronary Artery Anastomosi | 2004 |
[Behaviour of near-infrared cerebral oximetry readings during percutaneous carotid angioplasty].
Topics: Aged; Angioplasty, Balloon; Blood Pressure; Brain Ischemia; Carotid Artery, Internal; Carotid Stenos | 2006 |
13 other studies available for papaverine and Complication, Intraoperative
| Article | Year |
|---|---|
Transient pupillary dilation following local papaverine application in intracranial aneurysm surgery.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anterior Cerebral Artery; Craniotomy; Female; Functional | 2015 |
Comparing the Outcomes of Different Agents to Treat Vasospasm at Microsurgical Anastomosis during the Papaverine Shortage.
Topics: Administration, Topical; Aged; Anastomosis, Surgical; Drug Substitution; Female; Free Tissue Flaps; | 2016 |
Haemodynamic changes after intracisternal papaverine instillation during intracranial aneurysmal surgery.
Topics: Administration, Topical; Bradycardia; Humans; Hypotension; Intracranial Aneurysm; Intraoperative Com | 2006 |
Transient facial nerve palsy after topical papaverine application during vestibular schwannoma surgery. Case report.
Topics: Administration, Topical; Facial Paralysis; Female; Humans; Intraoperative Complications; Middle Aged | 2007 |
Effect of normothermic papaverine to relieve intraoperative spasm of the internal thoracic artery.
Topics: Administration, Topical; Adult; Aged; Blood Flow Velocity; Coronary Artery Bypass; Female; Humans; I | 1996 |
Failed coronary artery bypass anastomosis detected by intraoperative coronary flow measurement.
Topics: Aged; Blood Flow Velocity; Coronary Circulation; Coronary Disease; Epinephrine; Extracorporeal Circu | 1998 |
Intraoperative duplex monitoring of infrainguinal vein bypass procedures.
Topics: Anastomosis, Surgical; Arteries; Blood Flow Velocity; Constriction, Pathologic; Female; Fibrinolytic | 2000 |
Severe bronchospasm relieved by papaverine?
Topics: Bronchial Spasm; Child; Humans; Intraoperative Complications; Kidney Transplantation; Male; Papaveri | 2000 |
Complications associated with intraarterial administration of papaverine for vasospasm following subarachnoid hemorrhage--two case reports.
Topics: Adult; Carotid Arteries; Cerebral Angiography; Craniotomy; Dose-Response Relationship, Drug; Fatal O | 2000 |
Overcoming perioperative spasm of the internal mammary artery: which is the best vasodilator?
Topics: Administration, Topical; Female; Humans; Internal Mammary-Coronary Artery Anastomosis; Intraoperativ | 1992 |
Further observations on perioperative myocardial ischemia.
Topics: Blood Pressure; Cardiopulmonary Bypass; Coronary Artery Bypass; Coronary Circulation; Coronary Disea | 1986 |
Relief of blood-induced arterial vasospasm by pharmacologic solutions.
Topics: Amputation, Surgical; Animals; Blood; Hindlimb; Intraoperative Complications; Lidocaine; Microsurger | 1987 |
The use of topical vasodilators as an adjunct in infant renal surgery.
Topics: Administration, Topical; Female; Humans; Infant; Infant, Newborn; Intraoperative Care; Intraoperativ | 1985 |