papaverine has been researched along with Colonic Diseases in 2 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Colonic Diseases: Pathological processes in the COLON region of the large intestine (INTESTINE, LARGE).
| Excerpt | Relevance | Reference |
|---|---|---|
| " The bioavailability of the drug was highly variable with a mean of 28% (range 5-99%) but reproducible within the same individual (4 of the volunteers) after a repeated (80 mg) oral dose." | 1.27 | Variable bioavailability of papaverine. ( Berg, G; Hammar, M; Jönsson, KA; Norlander, B, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (100.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MAURO, R | 1 |
| MIRACCO, A | 1 |
| Berg, G | 1 |
| Jönsson, KA | 1 |
| Hammar, M | 1 |
| Norlander, B | 1 |
2 other studies available for papaverine and Colonic Diseases
| Article | Year |
|---|---|
[ON A NEW DIAGNOSTIC AND THERAPEUTIC TECHNIC OF COLON DISORDERS].
Topics: Chloramphenicol; Colitis; Colitis, Ulcerative; Colonic Diseases; Enema; Equipment and Supplies; Huma | 1964 |
Variable bioavailability of papaverine.
Topics: Administration, Oral; Adult; Biological Availability; Chromatography, High Pressure Liquid; Colonic | 1988 |