papaverine has been researched along with Colitis in 4 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
Colitis: Inflammation of the COLON section of the large intestine (INTESTINE, LARGE), usually with symptoms such as DIARRHEA (often with blood and mucus), ABDOMINAL PAIN, and FEVER.
| Excerpt | Relevance | Reference |
|---|---|---|
| " In the present study we examined the effects of a vasoconstrictor (pseudoephedrine) and a vasodilator (papaverine) on the outcome of DSS-induced colitis." | 7.74 | Contrasting effects of pseudoephedrine and papaverine in dextran sodium sulfate-induced colitis. ( Carter, PR; Harris, NR; Morgan, GA; Specian, RD, 2008) |
| " In the present study we examined the effects of a vasoconstrictor (pseudoephedrine) and a vasodilator (papaverine) on the outcome of DSS-induced colitis." | 3.74 | Contrasting effects of pseudoephedrine and papaverine in dextran sodium sulfate-induced colitis. ( Carter, PR; Harris, NR; Morgan, GA; Specian, RD, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (50.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| MAURO, R | 1 |
| MIRACCO, A | 1 |
| MAKLARI, L | 1 |
| Mori, M | 1 |
| Stokes, KY | 1 |
| Vowinkel, T | 1 |
| Watanabe, N | 1 |
| Elrod, JW | 1 |
| Harris, NR | 2 |
| Lefer, DJ | 1 |
| Hibi, T | 1 |
| Granger, DN | 1 |
| Specian, RD | 1 |
| Carter, PR | 1 |
| Morgan, GA | 1 |
4 other studies available for papaverine and Colitis
| Article | Year |
|---|---|
[ON A NEW DIAGNOSTIC AND THERAPEUTIC TECHNIC OF COLON DISORDERS].
Topics: Chloramphenicol; Colitis; Colitis, Ulcerative; Colonic Diseases; Enema; Equipment and Supplies; Huma | 1964 |
EXPERIENCE OBTAINED WITH A NEW SPASMOLYTIC DRUG (NO-SPA).
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Cholelithiasis; Colic; Colitis; Duodenal Ulcer; | 1963 |
Colonic blood flow responses in experimental colitis: time course and underlying mechanisms.
Topics: Animals; Arterioles; Bradykinin; Colitis; Colon; Depression, Chemical; Dextran Sulfate; Heart Rate; | 2005 |
Contrasting effects of pseudoephedrine and papaverine in dextran sodium sulfate-induced colitis.
Topics: Animals; Colitis; Colon; Dextran Sulfate; Disease Models, Animal; Drug Administration Routes; Male; | 2008 |