papaverine has been researched along with Colitis, Mucous in 5 studies
Papaverine: An alkaloid found in opium but not closely related to the other opium alkaloids in its structure or pharmacological actions. It is a direct-acting smooth muscle relaxant used in the treatment of impotence and as a vasodilator, especially for cerebral vasodilation. The mechanism of its pharmacological actions is not clear, but it apparently can inhibit phosphodiesterases and it may have direct actions on calcium channels.
papaverine : A benzylisoquinoline alkaloid that is isoquinoline substituted by methoxy groups at positions 6 and 7 and a 3,4-dimethoxybenzyl group at position 1. It has been isolated from Papaver somniferum.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This retrospective study investigated the effectiveness and safety of neuromuscular electrical stimulation (NMES) as an adjunctive therapy to drotaverine hydrochloride (DHC) in patients with diarrhea-predominant irritable bowel syndrome (BP-IBS)." | 7.88 | Neuromuscular electrical stimulation as an adjunctive therapy to drotaverine hydrochloride for treating patients with diarrhea-predominant irritable bowel syndrome: A retrospective study. ( Liu, J; Wang, JK, 2018) |
| "This study aimed to assess the efficacy and safety of drotaverine hydrochloride (DHC) in Chinese patients with irritable bowel syndrome (IBS)." | 7.85 | Randomized controlled study of efficacy and safety of drotaverine hydrochloride in patients with irritable bowel syndrome. ( Qi, XX; Wan, XY; Xue, XC, 2017) |
| " In the IBS subjects, pain severity, as well as the sensory response to rectal balloon distention and rectal and sigmoid motility, were studied at baseline and after two weeks therapy with either oral buscopan (20 mg three times a day, n=37), a buscopan suppository (30 mg once daily, n=21), oral drotaverine (80 mg three times a day, n=30), calcium gluconate tablets (one three times a day, n=16) as a control for oral agents, or calendula suppository (once daily, n=14) as a control for those who received a suppository." | 5.14 | Interactions between symptoms and motor and visceral sensory responses of irritable bowel syndrome patients to spasmolytics (antispasmodics). ( Dzhanayev, YA; Golovenko, OV; Khalif, IL; Makarchuk, PA; Podmarenkova, LF; Quigley, EM, 2009) |
| "This retrospective study investigated the effectiveness and safety of neuromuscular electrical stimulation (NMES) as an adjunctive therapy to drotaverine hydrochloride (DHC) in patients with diarrhea-predominant irritable bowel syndrome (BP-IBS)." | 3.88 | Neuromuscular electrical stimulation as an adjunctive therapy to drotaverine hydrochloride for treating patients with diarrhea-predominant irritable bowel syndrome: A retrospective study. ( Liu, J; Wang, JK, 2018) |
| "This study aimed to assess the efficacy and safety of drotaverine hydrochloride (DHC) in Chinese patients with irritable bowel syndrome (IBS)." | 3.85 | Randomized controlled study of efficacy and safety of drotaverine hydrochloride in patients with irritable bowel syndrome. ( Qi, XX; Wan, XY; Xue, XC, 2017) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 2 (40.00) | 29.6817 |
| 2010's | 3 (60.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Xue, XC | 1 |
| Qi, XX | 1 |
| Wan, XY | 1 |
| Wang, JK | 1 |
| Liu, J | 1 |
| Ruchkina, IN | 1 |
| Fadeeva, NA | 1 |
| Parfenov, AI | 1 |
| Shcherbakov, PL | 1 |
| Gubina, AV | 1 |
| Poleva, NI | 1 |
| Khomeriki, SG | 1 |
| Chikunova, BZ | 1 |
| Khalif, IL | 1 |
| Quigley, EM | 1 |
| Makarchuk, PA | 2 |
| Golovenko, OV | 1 |
| Podmarenkova, LF | 1 |
| Dzhanayev, YA | 1 |
3 trials available for papaverine and Colitis, Mucous
| Article | Year |
|---|---|
[The role of small bowel microflora in the development of secondary lactase deficiency and the possibilities of its treatment with probiotics].
Topics: Adult; Analgesics; Bifidobacterium; Blind Loop Syndrome; Enterococcus faecium; Female; Humans; Intes | 2013 |
Interactions between symptoms and motor and visceral sensory responses of irritable bowel syndrome patients to spasmolytics (antispasmodics).
Topics: Administration, Oral; Administration, Rectal; Adult; Butylscopolammonium Bromide; Calcium Gluconate; | 2009 |
[Dynamics of indices of visceral sensitivity in patients with irritable bowel syndrome treated with spasmolytics].
Topics: Abdominal Pain; Adult; Butylscopolammonium Bromide; Female; Humans; Hyperalgesia; Irritable Bowel Sy | 2007 |
2 other studies available for papaverine and Colitis, Mucous
| Article | Year |
|---|---|
Randomized controlled study of efficacy and safety of drotaverine hydrochloride in patients with irritable bowel syndrome.
Topics: Administration, Oral; Adult; Aged; Chi-Square Distribution; China; Dose-Response Relationship, Drug; | 2017 |
Neuromuscular electrical stimulation as an adjunctive therapy to drotaverine hydrochloride for treating patients with diarrhea-predominant irritable bowel syndrome: A retrospective study.
Topics: Adult; Combined Modality Therapy; Diarrhea; Electric Stimulation Therapy; Female; Humans; Irritable | 2018 |